1,224 research outputs found

    Observation of surface states on heavily indium doped SnTe(111), a superconducting topological crystalline insulator

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    The topological crystalline insulator tin telluride is known to host superconductivity when doped with indium (Sn1−x_{1-x}Inx_{x}Te), and for low indium contents (x=0.04x=0.04) it is known that the topological surface states are preserved. Here we present the growth, characterization and angle resolved photoemission spectroscopy analysis of samples with much heavier In doping (up to x≈0.4x\approx0.4), a regime where the superconducting temperature is increased nearly fourfold. We demonstrate that despite strong p-type doping, Dirac-like surface states persist

    Monte Carlo Simulation Calculation of Critical Coupling Constant for Continuum \phi^4_2

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    We perform a Monte Carlo simulation calculation of the critical coupling constant for the continuum {\lambda \over 4} \phi^4_2 theory. The critical coupling constant we obtain is [{\lambda \over \mu^2}]_crit=10.24(3).Comment: 11 pages, 4 figures, LaTe

    Malrotation in patients with duodenal atresia: A true association or an expected finding on postoperative upper gastrointestinal barium study?

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    We retrospectively reviewed the imaging and surgical findings in 17 patients with duodenal atresia to determine (a) the frequency of coexistent malrotation in patients with duodenal atresia and (b) the reliability of the upper gastrointestinal barium study (UGI) in differentiating malrotation from postoperative deformity of the duodenal sweep after repair of duodenal atresia. Postoperatively, 9 (53%) of the 17 patients had UGI findings consistent with malrotation. Of these nine, only two had malrotation coexistent with duodenal atresia, while the other seven had normal midgut rotation demonstrated intraoperatively. The radiographic appearance of malrotation was simulated in two patients in whom the ligament of Treitz had been surgically divided, in three in whom the ligament had not been taken down, and in two in whom the status of the ligament was not specified in the surgical report. Although there is an association between duodenal atresia and malrotation, this cannot be accurately documented on postoperative UGI examination. Malrotation cannot be detected preoperatively because contrast material cannot pass beyond the level of the atresia. Postoperatively, surgical deformity of the duodenal sweep cannot be reliably distinguished from malrotation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46705/1/247_2005_Article_BF02012180.pd

    The human complement system in thrombin-mediated platelet function.

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    Effective Monopole Potential for SU(2) Lattice Gluodynamics in Spatial Maximal Abelian Gauge

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    We investigate the dual superconductor hypothesis in finite-temperature SU(2) lattice gluodynamics in the Spatial Maximal Abelian gauge. This gauge is more physical than the ordinary Maximal Abelian gauge due to absence of non-localities in temporal direction. We show numerically that in the Spatial Maximal Abelian gauge the probability distribution of the abelian monopole field is consistent with the dual superconductor mechanism of confinement: the abelian condensate vanishes in the deconfinement phase and is not zero in the confinement phase.Comment: LaTeX2e, 8 pages with 3 EPS figures, uses epsf.st

    Negative-Energy Spinors and the Fock Space of Lattice Fermions at Finite Chemical Potential

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    Recently it was suggested that the problem of species doubling with Kogut-Susskind lattice fermions entails, at finite chemical potential, a confusion of particles with antiparticles. What happens instead is that the familiar correspondence of positive-energy spinors to particles, and of negative-energy spinors to antiparticles, ceases to hold for the Kogut-Susskind time derivative. To show this we highlight the role of the spinorial ``energy'' in the Osterwalder-Schrader reconstruction of the Fock space of non-interacting lattice fermions at zero temperature and nonzero chemical potential. We consider Kogut-Susskind fermions and, for comparison, fermions with an asymmetric one-step time derivative.Comment: 14p

    A structural basis for IÎșB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation.

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    Activation of the IÎșB kinase (IKK) is central to NF-ÎșB signaling. However, the precise activation mechanism by which catalytic IKK subunits gain the ability to induce NF-ÎșB transcriptional activity is not well understood. Here we report a 4 Å x-ray crystal structure of human IKK2 (hIKK2) in its catalytically active conformation. The hIKK2 domain architecture closely resembles that of Xenopus IKK2 (xIKK2). However, whereas inactivated xIKK2 displays a closed dimeric structure, hIKK2 dimers adopt open conformations that permit higher order oligomerization within the crystal. Reversible oligomerization of hIKK2 dimers is observed in solution. Mutagenesis confirms that two of the surfaces that mediate oligomerization within the crystal are also critical for the process of hIKK2 activation in cells. We propose that IKK2 dimers transiently associate with one another through these interaction surfaces to promote trans auto-phosphorylation as part of their mechanism of activation. This structure-based model supports recently published structural data that implicate strand exchange as part of a mechanism for IKK2 activation via trans auto-phosphorylation. Moreover, oligomerization through the interfaces identified in this study and subsequent trans auto-phosphorylation account for the rapid amplification of IKK2 phosphorylation observed even in the absence of any upstream kinase
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