Do three years make a difference? An updated review and analysis of self-initiated expatriation

Self-initiated expatriates (SIEs) were initially described by Inkson et al. (J World Bus 32: 351-368, 1997) as individuals who move abroad on their own volition, with personal funding, oriented towards development and career goals. After almost two decades of research, it is imperative to review the knowledge that has been developed and identify future areas of intervention. Doherty (Int J Manag Rev 15: 447-469, 2013. doi: 10.1111/ijmr.12005) initiated the review and this paper aims to update it and explore some unapproached aspects. Five different data bases were targeted and searched for peer-reviewed articles published in English, between 1997 and 2014, which recognized self-initiated expatriation as a distinguished form of mobility and used this terminology in the title and/or keywords list. A total of 94 articles met these inclusion criteria, 45 of which were published between 2012 and 2014. By systematically analyzing them, it was observed a surpassing growth in the number of published articles in the last 3 years. This signalizes an increase of the academic interest in studying the SIEs all over the world, involving bidirectional moves between developed and developing countries. The constructs identified by Doherty (2013) at the three different levels (micro, meso and macro) continued to be explored, using qualitative or quantitative approaches. Besides this, a multi-informant approach has been adopted in some studies, while others focused on concept clarification, taking into consideration some of Doherty's (2013) suggestions for future research. Three years of research made an enormous contribution to the development of knowledge about SIEs, but some aspects can be further explored; hence they are identified and thoroughly discussed.info:eu-repo/semantics/publishedVersio

Motivations and cross-cultural adaptation of self-initiated expatriates, assigned expatriates, and immigrant workers: the case of Portuguese migrant workers in the United Kingdom

Only in recent years have immigrant workers, assigned expatriates, and self-initiated expatriates been distinguished from each other. This study contributes by offering empirically based comparative results based on interviews with 50 Portuguese citizens who moved to the United Kingdom, as self-initiated expatriates, assigned expatriates, and immigrant workers. The findings indicate that Portuguese self-initiated expatriates and assigned expatriates explored their opportunities before leaving Portugal, while immigrant workers explored them after arriving in the United Kingdom. Self-initiated expatriates and immigrant workers were driven by poor labor market situation in Portugal (e.g., unemployment, unchallenging tasks), but pull factors (e.g., professional international experience) were also identified as dominant motivators for both types of expatriates. Participants generally felt that their adaptation was easy in terms of the general (e.g., climate, food) and working (e.g., knowing one’s role and job related activities) environments. Some self-initiated expatriates and immigrant workers noted that their adaptation to interactions with locals and to accommodation was difficult. Patterns emerged linking the three types of migrant workers with motivational drivers for moving abroad and perceptions of cross-cultural adaptation. We discuss these patterns in the light of previous findings and identify future research areas

Differences between ethnic and non ethnic-specific clinics for Portuguese-speaking mental health patients explained by providers

Background: A previous quantitative study conducted in a health care system in a Northeastern U.S. metropolitan area identified greater adequacy of mental health care for Portuguese-speaking patients at a ethnic-specific Portuguese Mental Health Program (PMHP) compared to non ethnic-specific clinics. The objective of the present study was to understand, from a provider perspective, the disadvantages and difficulties of treating Portuguese-speaking immigrants with mental illness, and to elicit recommendations for improving care for this population. Methods: We conducted three interviews with providers using a structured interview guide that elicited questions related to the clinic, its patients, provider’s work, and ways in which the providers tailored mental health services to the Portuguese-speaking population. Responses were analyzed using content analysis, recording the frequency and saliency of particular words and phrases, and identifying keywords or repeated ideas. Results: Providers reported that the PMHP clinic is successful because it offers a unique set of services, provides services in the Portuguese language 100% of the time, and has existed for a long time in their community. Important differences between patients from Portugal and patients from Brazil include demographic characteristics, and patients’ and relatives’ feelings about seeking mental health treatment. Conclusion: This study supports policy recommendations to expand the availability of ethnic specific clinics. These clinics may play an especially important role in cost reduction and quality enhancement efforts being undertaken in urban safety net hospitals that serve a large number of individuals of racial/ethnic minority background.info:eu-repo/semantics/publishedVersio

Advocacy for youth mental health in Europe: a policy analysis

Background: According to both the WHO Europe and the European Commission, youth mental health is a key area of concern in Europe. Fifty-two European countries signed a declaration and action plan for mental health at the Helsinki Conference in January 2005, with youth mental health a top priority. Methods: This paper reviews the theory, research, and practice on the topic in the WHO European Region and presents important implications for policy, research, and practice. It states problems related to youth mental health and then discusses different ways of solving them with policy. Results: Mental illness, especially emotional and conduct problems, as well as learning disabilities, is growing among European children and adolescents. However, stigma continues to be a significant barrier to effective promotion of youth mental health. Stigma can be related to others' perceptions of youth with mental distress, perceptions of mental health workers, perceptions of mental health treatment, and perceptions of mental health/illness itself. Conclusion: Advocacy to reduce stigma in health service settings, schools, and policy arenas can be an effective means by which to effect cultural change regarding mental health issues.info:eu-repo/semantics/publishedVersio

The research-teaching nexus from the Portuguese academics’ perspective: a qualitative case study in a school of social sciences and humanities

This paper reports on a study conducted as part of an action-research project—INTEGRA I&E—aiming to promote the research and teaching (R&T) nexus at the School of Social Sciences and Humanities of a Research University in Lisbon, Portugal (Instituto Universitário de Lisboa, ISCTE-IUL). This study set out to investigate a multi-informant perspective of the academics’ rhetoric (conceptions, perception of barriers/facilitators and consequences) concerning the nexus, which can be considered at different levels of the curricular and organizational structure. Focus groups were conducted with 26 professors and 8 researchers from six different disciplinary areas and, afterwards, recorded and transcribed. A content analysis was used to categorize and quantify participants’ responses. Four themes emerged: practices linking R&T, barriers, facilitators and consequences of the nexus. Different levels of analysis were identified for each theme, namely, the level of ISCTE-IUL, Research Centers, Departments, Courses and Classes. Some disciplinary differences were also encountered. This study contributes with a multi-informant and multi-level perspective of academics’ conceptions of the R&T nexus in a Portuguese research-oriented university.info:eu-repo/semantics/acceptedVersio

Synthesis and photophysical characteristics of polyfluorene polyrotaxanes

Two alternating polyfluorene polyrotaxanes (3·TM-βCD and 3·TM-γCD) have been synthesized by the coupling of 2,7-dibromofluorene encapsulated into 2,3,6-tri-O-methyl-β- or γ-cyclodextrin (TM-βCD, TM-γCD) cavities with 9,9-dioctylfluorene-2,7-diboronic acid bis(1,3-propanediol) ester. Their optical, electrochemical and morphological properties have been evaluated and compared to those of the non-rotaxane counterpart 3. The influence of TM-βCD or TM-γCD encapsulation on the thermal stability, solubility in common organic solvents, film forming ability was also investigated. Polyrotaxane 3·TM-βCD exhibits a hypsochromic shift, while 3·TM-γCD displays a bathochromic with respect to the non-rotaxane 3 counterpart. For the diluted CHCl3 solutions the fluorescence lifetimes of all compounds follow a mono-exponential decay with a time constant of ≈0.6 ns. At higher concentration the fluorescence decay remains mono-exponential for 3·TM-βCD and polymers 3, with a lifetime τ = 0.7 ns and 0.8 ns, whereas the 3·TM-γCD polyrotaxane shows a bi-exponential decay consisting of a main component (with a weight of 98% of the total luminescence) with a relatively short decay constant of τ1 = 0.7 ns and a minor component with a longer lifetime of τ2 = 5.4 ns (2%). The electrochemical band gap (ΔEg) of 3·TM-βCD polyrotaxane is smaller than that of 3·TM-γCD and 3, respectively. The lower ΔEg value for 3·TM-βCD suggests that the encapsulation has a greater effect on the reduction process, which affects the LUMO energy level value. Based on AFM analysis, 3·TM-βCD and 3·TM-γCD polyrotaxane compounds exhibit a granular morphology with lower dispersity and smaller roughness exponent of the film surfaces in comparison with those of the neat copolymer 3

The cohesin ring concatenates sister DNA molecules

Sister chromatid cohesion, which is essential for mitosis, is mediated by a multi-subunit protein complex called cohesin whose Scc1, Smc1, and Smc3 subunits form a tripartite ring structure. It has been proposed that cohesin holds sister DNAs together by trapping them inside its ring. To test this, we used site-specific cross-linking to create chemical connections at the three interfaces between the ring’s three constituent polypeptides, thereby creating covalently closed cohesin rings. As predicted by the ring entrapment model, this procedure produces dimeric DNA/cohesin structures that are resistant to protein denaturation. We conclude that cohesin rings concatenate individual sister minichromosome DNAs

Severe Acute Respiratory Syndrome–associated Coronavirus in Lung Tissue

Efforts to contain severe acute respiratory syndrome (SARS) have been limited by the lack of a standardized, sensitive, and specific test for SARS-associated coronavirus (CoV). We used a standardized reverse transcription-polymerase chain reaction assay to detect SARS-CoV in lung samples obtained from well-characterized patients who died of SARS and from those who died of other reasons. SARS-CoV was detected in all 22 postmortem lung tissues (to 109 viral copies/g) from 11 patients with probable SARS but was not detected in any of the 23 lung control samples (sample analysis was blinded). The sensitivity and specificity (95% confidence interval) were 100% (84.6% to 100%) and 100% (85.1% to 100%), respectively. Viral loads were significantly associated with a shorter course of illness but not with the use of ribavirin or steroids. CoV was consistently identified in the lungs of all patients who died of SARS but not in control patients, supporting a primary role for CoV in deaths

CYberinfrastructure for COmparative effectiveness REsearch (CYCORE): improving data from cancer clinical trials

Improved approaches and methodologies are needed to conduct comparative effectiveness research (CER) in oncology. While cancer therapies continue to emerge at a rapid pace, the review, synthesis, and dissemination of evidence-based interventions across clinical trials lag in comparison. Rigorous and systematic testing of competing therapies has been clouded by age-old problems: poor patient adherence, inability to objectively measure the environmental influences on health, lack of knowledge about patients’ lifestyle behaviors that may affect cancer’s progression and recurrence, and limited ability to compile and interpret the wide range of variables that must be considered in the cancer treatment. This lack of data integration limits the potential for patients and clinicians to engage in fully informed decision-making regarding cancer prevention, treatment, and survivorship care, and the translation of research results into mainstream medical care. Particularly important, as noted in a 2009 report on CER to the President and Congress, the limited focus on health behavior-change interventions was a major hindrance in this research landscape (DHHS 2009). This paper describes an initiative to improve CER for cancer by addressing several of these limitations. The Cyberinfrastructure for Comparative Effectiveness Research (CYCORE) project, informed by the National Science Foundation’s 2007 report “Cyberinfrastructure Vision for 21st Century Discovery” has, as its central aim, the creation of a prototype for a user-friendly, open-source cyberinfrastructure (CI) that supports acquisition, storage, visualization, analysis, and sharing of data important for cancer-related CER. Although still under development, the process of gathering requirements for CYCORE has revealed new ways in which CI design can significantly improve the collection and analysis of a wide variety of data types, and has resulted in new and important partnerships among cancer researchers engaged in advancing health-related CI

Comparison of different methods for delayed post-mortem diagnosis of falciparum malaria

<p>Abstract</p> <p>Background</p> <p>Between 10,000 and 12,000 cases of imported malaria are notified in the European Union each year. Despite an excellent health care system, fatalities do occur. In case of advanced autolysis, the post-mortem diagnostic is impaired. Quicker diagnosis could be achieved by using rapid diagnostic malaria tests.</p> <p>Methods</p> <p>In order to evaluate different methods for the post-mortem diagnosis of <it>Plasmodium falciparum </it>malaria in non-immunes, a study was performed on the basis of forensic autopsies of corpses examined at variable intervals after death in five cases of fatal malaria (with an interval of four hours to five days), and in 20 cases of deaths unrelated to malaria. Detection of parasite DNA by PCR and an immunochromatographic test (ICT) based upon the detection of <it>P. falciparum </it>histidine-rich protein 2 (PfHRP2) were compared with the results of microscopic examination of smears from cadaveric blood, histopathological findings, and autopsy results.</p> <p>Results</p> <p>In all cases of fatal malaria, post-mortem findings were unsuspicious for the final diagnosis, and autoptic investigations, including histopathology, were only performed because of additional information by police officers and neighbours. Macroscopic findings during autopsy were unspecific. Histopathology confirmed sequestration of erythrocytes and pigment in macrophages in most organs in four patients (not evaluable in one patient due to autolysis). Microscopy of cadaveric blood smears revealed remnants of intraerythrocytic parasites, and was compromised or impossible due to autolysis in two cases. PCR and ICT performed with cadaveric blood were positive in all malaria patients and negative in all controls.</p> <p>Conclusion</p> <p>In non-immune fatalities with unclear anamnesis, ICT can be recommended as a sensitive and specific tool for post-mortem malaria diagnosis, which is easier and faster than microscopy, and also applicable when microscopic examination is impossible due to autolysis. PCR is more expensive and time-consuming, but may be used as confirmatory test. In highly endemic areas where asymptomatic parasitaemia is common, confirmation of the diagnosis of malaria as the cause of death has to rely on histopathological findings.</p