80 research outputs found
A personal text owned by its public— changing readings of Sarah Raal’s Met die Boere in die Veld
What seems to be a typical feature of Boer women’s personal texts which refer to the Anglo-Boer War (1899–1902) is the militant rhetoric of protest against the British aggression. Met die Boere in die Veld (“With the Boers in the Veld”) by Sarah Raal is a perfect example of this trend. Yet, her case is unique, because she actually spent a part of the war in the veld, fighting side by side with her brothers, which definitely was not a traditional place for a woman during a military conflict. Her memoirs were published for the first time in the 1930s, reprinted a number of times, and re-issued in 2000 in two language editions— Afrikaans and English (significantly under a new title, The Lady who Fought). An additional introduction was added to both new editions, which suggests a new role of the heroine and a new meaning of her story. This paper discusses how Raal’s original foreword and the new introduction influence the reader’s response to the text. Additionally, attention is drawn to the role of other paratextual elements of the book and the matter of translation. Having taken into account political and gender discourses operating as a context for every reading, the text undergoes re-interpretations. Consequently, the book, once an anti-British Afrikaner nationalist propaganda story, turns into a popular adventure tale about a brave Boer girl, a story about an exceptional woman, a proto-feminist who transgresses the conventional gender roles, or into a universal pacifist protest. In the 2000 edition pacifist and feminist aspects come to the foreground, and this way the old story becomes a suitable read for the modern post-apartheid reader.Keywords: Anglo-Boer War, life writing, reader’s response, paratext, Sarah Raal
Link Mining for Kernel-based Compound-Protein Interaction Predictions Using a Chemogenomics Approach
Virtual screening (VS) is widely used during computational drug discovery to
reduce costs. Chemogenomics-based virtual screening (CGBVS) can be used to
predict new compound-protein interactions (CPIs) from known CPI network data
using several methods, including machine learning and data mining. Although
CGBVS facilitates highly efficient and accurate CPI prediction, it has poor
performance for prediction of new compounds for which CPIs are unknown. The
pairwise kernel method (PKM) is a state-of-the-art CGBVS method and shows high
accuracy for prediction of new compounds. In this study, on the basis of link
mining, we improved the PKM by combining link indicator kernel (LIK) and
chemical similarity and evaluated the accuracy of these methods. The proposed
method obtained an average area under the precision-recall curve (AUPR) value
of 0.562, which was higher than that achieved by the conventional Gaussian
interaction profile (GIP) method (0.425), and the calculation time was only
increased by a few percent
Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials
BACKGROUND: Acyclovir has the potential to shorten the course of chickenpox which may result in reduced costs and morbidity. We conducted a systematic review of randomised controlled trials that evaluated acyclovir for the treatment of chickenpox in otherwise healthy children. METHODS: MEDLINE, EMBASE, and the Cochrane Library were searched. The reference lists of relevant articles were examined and primary authors and Glaxo Wellcome were contacted to identify additional trials. Two reviewers independently screened studies for inclusion, assessed study quality using the Jadad scale and allocation concealment, and extracted data. Continuous data were converted to a weighted mean difference (WMD). Overall estimates were not calculated due to differences in the age groups studied. RESULTS: Three studies were included. Methodological quality was 3 (n = 2) and 4 (n = 1) on the Jadad scale. Acyclovir was associated with a significant reduction in the number of days with fever, from -1.0 (95% CI -1.5,-0.5) to -1.3 (95% CI -2.0,-0.6). Results were inconsistent with respect to the number of days to no new lesions, the maximum number of lesions and relief of pruritis. There were no clinically important differences between acyclovir and placebo with respect to complications or adverse effects. CONCLUSION: Acyclovir appears to be effective in reducing the number of days with fever among otherwise healthy children with chickenpox. The results were inconsistent with respect to the number of days to no new lesions, the maximum number of lesions and the relief of itchiness. The clinical importance of acyclovir treatment in otherwise healthy children remains controversial
Investigations, analysis and assessment of certain aspects of thermo-mechanical and chemical resistance of graphite nozzles to action of combustion products of sustaining solid rocket propellant charges applied in propulsion systems of GROM missiles
W artykule przedstawiono pewne aspekty badania, analizy i oceny odporności termomechanicznej i chemicznej dysz grafitowych zbudowanych z wkładki pirografitowej oraz korpusu z grafitu polikrystalicznego, na działanie produktów spalania marszowego ładunku przeciwlotniczego pocisku rakietowego GROM. We wstępnej fazie badań wykonano analizę modelu spalania heterogenicznego paliwa rakietowego tworzącego ładunek marszowy układu napędowego pocisku GROM, w określonych warunkach pracy silnika rakietowego. Rzeczywistą odporność dysz na erozyjne działanie strumienia produktów spalania określano za pomocą diagnostycznego systemu radioskopowego czasu rzeczywistego poprzez porównanie zmian profilu przekroju kanału przelotowego dyszy, a zwłaszcza średnicy krytycznej kanału przed oraz po stacjonarnych badaniach spalaniem ładunków marszowych pocisku GROM w grubościennych komorach spalania.In this paper there are presented certain aspects of investigations, analyses and assessments dealing with thermo-mechanical and chemical resistance of nozzles composed of pyrographite insert and body made from polycrystalline graphite. The nozzles were considered in terms of their thermo-mechanical and chemical resistance against combustion products of sustaining propellant charge applied in propulsion system of antiaircraft missile GROM. In initial stage of investigations, it was conducted analysis of combustion model of heterogeneous rocket propellant of composition corresponding to composition of real sustaining propulsive charge of missile GROM, under assumed conditions of rocket motor operation. Real resistance of graphite nozzles against action of combustion products, was determined by means of real time radiography (RTR) on the basis of comparison of nozzle duct section profile changes before and after static firing tests with usage of GROM missile sustaining propellant charges inserted in thick-walled combustion chamber
Certain aspects of testing artillery fuses by X-ray
W artykule przedstawiono nieniszczące badania strukturalne oraz materiałowe wybranych typów zapalników artyleryjskich - głowicowych i dennych - znajdujących się na wyposażeniu Sił Zbrojnych RP, za pomocą diagnostycznego systemu radioskopii czasu rzeczywistego (RTR – Real Time Radioscopy). Szczególną uwagę poświęcono badaniu łańcuchów ogniowych zapalników pod kątem bezpieczeństwa ich eksploatacji i niezawodności działania. W wyniku tych badań opracowano wytyczne do procedur diagnozowania zapalników artyleryjskich za pomocą techniki RTR w zakresie prawidłowości usytuowania, rozmieszczenia, zwartości oraz jednorodności materiałowej elementów składowych łańcucha ogniowego, takich jak iglice, ich obsady, sprężyny, spłonki zapalające, pobudzające, opóźniacze pirotechniczne, pobudzacze (detonatory) oraz mechanizmy zabezpieczające.Structure and material nondestructive tests of selected types of artillery fuses – head and bottom ones being in service in Polish Armed Forces – by means of Real Time Radioscopy (RTR) diagnostic system, were presented. Particular attention was paid to firing/explosive trains of tested fuses, taking into consideration their safety and suitability usage incl. reliability functioning. As a result of these tests, several recommendations to diagnostic procedures for fuses, were developed with RTR usage, in terms of examination of arrangement, location, position correctness and compactness and material homogenity of components of firing/explosive train, such as firing pins, their housings, springs, firing caps, detonating caps, pyrotechnic delayers, boosters (detonators) and safety mechanisms
Energy-optimal current distribution in a complex linear electrical network with pulse or periodic voltage and current signals. Optimal control
The article presents that in the circuits of electrical signals belonging to the L1-impulses space or periodic signals space, real distribution of electrical currents occurs which does not meet the principle of minimum energy losses. The paper presents a solution of this problem by using the control system in the form of current-dependent voltage sources entering it into a meshes set of a complex RLC network. It has been shown that the control is energy-neutral
The digital function filters – algorithms and applications
The simple digital filters are not sufficient for digital modeling of systems with distributed parameters. It is necessary to apply more complex digital filters. In this work, a set of filters, called the digital function filters, is proposed. It consists of digital filters, which are obtained from causal and stable filters through some function transformation. In this paper, for several basic functions: exponential, logarithm, square root and the real power of input filter, the recursive algorithms of the digital function filters have been determined The digital function filters of exponential type can be obtained from direct recursive formulas. Whereas, the other function filters, such as the logarithm, the square root and the real power, require using the implicit recursive formulas. Some applications of the digital function filters for the analysis and synthesis of systems with lumped and distributed parameters (a long line, phase shifters, infinite ladder circuits) are given as well
The wave transformer – analysis and application of time digital filters and the integral-derivative operators of ½ order
In this paper the way of modeling phenomena occurring during the voltage and current waves passing through a point connection of two lines, with different wave impedance operators, is presented. This connection point is called „the wave transformer”. The analyzes and the resulting formulas concern not the frequency domain, but the time domain. The appropriate transition matrices of waves through the wave transformer are defined. This matrices are the convolution integral-derivative operators of fractional order (the digital filters). For a lossless line the wave transition matrices through the wave transformer become number type instead of operator type. All matrix multiplications occurring in the formulas should be understood in convolution way
Energy-optimal current distribution in an electrical network – controlling by the differential or the integral systems
In the complex RLC network, apart from the currents flows arising from the normal laws of Kirchhoff, other distributions of current, resulting from certain optimization criteria, may also be received. This paper is the development of research on distribution that meets the condition of the minimum energy losses within the network called energy-optimal distribution. Optimal distribution is not reachable itself, but in order to trigger it off, it is necessary to introduce the control system in current-dependent voltage sources vector, entered into a mesh set of a complex RLC network. For energy-optimal controlling, to obtain the control operator, the inversion of R(s) operator is required. It is the matrix operator and the dispersive operator (it depends on frequency). Inversion of such operators is inconvenient because it is algorithmically complicated. To avoid this the operator R(s) is replaced by the R’ operator which is a?matrix, but non-dispersive one (it does not depend on s). This type of control is called the suboptimal control. Therefore, it is important to make appropriate selection of the R’ operator and hence the suboptimal control. This article shows how to implement such control through the use of matrix operators of multiple differentiation or integration. The key aspect is the distribution of a single rational function H(s) in a series of ‘s’ or ‘s1’. The paper presents a new way of developing a given, stable rational transmittance with real coefficients in power series of ‘s/s1. The formulas to determine values of series coefficients (with ‘s/s1’) have been shown and the conditions for convergence of differential/integral operators given as series of ‘s/s1’ have been defined
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