Tyrosine phosphorylation controls brassinosteroid receptor activation by triggering membrane release of its kinase inhibitor

Receptor tyrosine kinases control many critical processes in metazoans, but these enzymes appear to be absent in plants. Recently, two Arabidopsis receptor kinases-BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE1 (BAK1), the receptor and coreceptor for brassinosteroids-were shown to autophosphorylate on tyrosines. However, the cellular roles for tyrosine phosphorylation in plants remain poorly understood. Here, we report that the BRI1 KINASE INHIBITOR 1 (BKI1) is tyrosine phosphorylated in response to brassinosteroid perception. Phosphorylation occurs within a reiterated [KR][KR] membrane targeting motif, releasing BKI1 into the cytosol and enabling formation of an active signaling complex. Our work reveals that tyrosine phosphorylation is a conserved mechanism controlling protein localization in all higher organisms

Assessing Compliance to Covid-19 Protocols Among Licensed Hospitality Providers in the Ho Municipality of the Volta Region of Ghana

The present study assessed compliance with COVID-19 prevention protocols in the hospitality industry in the Ho Municipality of the Volta Region of Ghana. The study employed secondary data gathered in February 2021 from a 3-day field exercise undertaken by the Ghana Tourism Authority on the compliance of the Safety Protocols on the COVID-19 pandemic by operators in the hospitality industry. A total of sixty units (20 hotels, 20 local restaurants, and 20 Drinking Bars) were selected using a mixture of probability and non-probability sampling techniques such as stratified, purposive, and simple random sampling. The resulting data gathered using structured questionnaire and observations were coded and entered into SPSS for analysis. Results showed that all sectors and units were adhering to the proposed safety protocols to an appreciable extent. The study made recommendations in line with WHO standard protocols for preventing the spread of the virus and regular monitoring of hospitality facilities in the municipality and beyond to ensure compliance

Understanding components of entrepreneurial ecosystems

[No abstract available

Fuzzy Approach for Bibliometric Analysis of Publication Trends on Intragastric Balloon as a Minimally Invasive Procedure for Weight Loss in Obese Individuals

Part 12: FuzzyInternational audienceIn this paper, we perform Bibliometric assessment of research output that has been carried out pertaining to the literature on intragastric balloon (IGBs) as a treatment modality of morbid obesity. To do this, we conducted a bibliometric analysis on this topic using the growth of publications, publication trends over time, annual research productivity and authors’ activity as main outcome points. Furthermore, we validate the comparable applicability of Lotka’s law among authors with a single publication and those with multiple ones using a fuzzy approach. The analysis shows that publication trend follows Price’s law. The extracted trend is exponential and in accordance with what is found in other studies. Lotka’s formula using one and two publications, is found to hold but for mean $$x = 3.025$$x=3.025