Experience du service de medecine nucleaire sahloul sousse dans la prise en charge des carcinomes differencies de la thyroïde a thyroglobuline elevee.

But : L’objectif de notre travail est de présenter notre expérience dans la prise en charge des cancer différencié de la thyroïde (CDT) à Thyroglobuline (Tg) élevée, tout en identifiant les paramètres modifiant l’efficacité de l’Irathérapie et la valeur seuil de la Tg permettant avec un balayage post thérapeutique négatif de conclure à une rémission.Matériels et méthodes : Il s’agit d’une étude rétrospective portant sur 150 patients opérés pour CDT, suivis entre 1990 et 2006 et présentant une Tg>2ng/ml.Résultats : Il s’agit de 122 femmes et 28 hommes. L’âge moyen était de 52 ans. La Tg ne dépendait pas du type histologique mais il existait une relation statistiquement significative entre la Tg et la taille tumorale, l’atteinte ganglionnaire, l’extension locorégionale, la présence de métastases et le stade TNM. La réponse thérapeutique des CDT avec une Tg élevée dépendait de l’âge des patients, des caractéristiques anatomopathologiques de la tumeur et des valeurs de la Tg.Conclusion : L’efficacité ablative est optimisée par des cures d’iode 131 qui doivent être prolongées tant que la Tg reste élevée. La surveillance à vie, au cours de la quelle on exige des seuils de Tg infèrieurs à 2ng/ml, est nécessaire. Mots clés : Cancers différenciés de la thyroide, Thyroglobuline, Irathérapie, Pronostic, Surveillance.Purpose: The aim of our work is to present our experience in the management of differentiated thyroid cancer (DTC) with high thyroglobulin (Tg) , to identify parameters changing iodine effectiveness and Tg threshold with negative post treatment scan conclude to remission.Materials and Methods: This is a retrospective study of 150 patients undergoing CDT, followed between 1990 and 2006 and having a Tg > 2ng/ml .Results: Our study concerns 122 women and 28 men. The average age was 52 years . Tg value does not depend on the histological type but there was a statistically significant relationship between Tg and tumor size, lymph node involvement, locoregional , metastasis and TNM stage . The therapeutic response of CDT with a high Tg was dependent on the age of patients, the pathological characteristics of the tumor and the Tg values ofConclusion: The ablative efficiency is optimized by 131 cures iodine should be extended until the Tg remains high. Monitoring life is necessary and the thresholds Tg below 2ng/ml is required.Keywords: Differentiated thyroid Cancers, Thyroglobulin, Iodine 131, Prediction, Monitoring

Parameters Selection for the Production of Fully Dense Metals Processed by Selective Laser Melting

Selective laser melting (SLM) presents significant assets for both industrial and academic fields. However, the process parameters selection is yet challenging. It presents tens of parameters to be carefully selected, including laser power and speed, bed thickness, hatching space, and other parameters, for the manufacturing of parts with high density. This paper provides a deeper understanding of the processing parameters’ effect on the evolution of the product’s density. A series of numerical simulations of porosity is achieved on Ansys Additive© software and it shows the evolution of the relative density at different laser powers and scan speeds. Numerical results show that low laser power and accelerated scan lead to the generation of a small melt pool, and consequently low density. In the opposite case, at high power and slow scan, the created melt pool is wide enough to avoid porosity and generate fully dense products. The product density is proportionally related to the melt pool size. Hence, it could be estimated through the correlation with the melt pool width, which enables the perfect selection of the hatching space for the selected set of parameters

Les tumeurs parotidiennes

Objectif : Les tumeurs des glandes salivaires sont rares, dominées en fréquence par les tumeurs parotidiennes. elles sont caractérisées par une grande hétérogénéité morpho-histologique. Les formes bénignes sont les plus fréquentes dominées par l’adénome pléomorphe. Le traitement de ces tumeurs demeure chirurgical en premier lieu.Matériel et méthodes: Cette étude est rétrospective portant sur 47 cas de tumeurs parotidiennes sur une période de 10 ans (janvier 2000 à décembre 2009). L’étude des dossiers nous a permis de relever toutes les données cliniques et thérapeutiques. Notre recul est de deux ans.Résultats : L’âge moyen de nos patients était de 42 ans avec un sex-ratio de 2,58. Les tumeurs bénignes représentaient 89 % et 11 % étaient malignes. L’adénome pléomorphe était la tumeur bénigne la plus fréquente. La tumeur maligne la plus commune était le carcinome muco-épidermoïde. Le traitement de choix est la parotidectomie partielle ou totale. Cependant, la paralysie du nerf facial reste la complication principale de la chirurgie parotidienne.Conclusion : Les formes bénignes sont prédominante s, dont le plus fréquent demeure l’adénome pléomorphe. L’imagerie moderne permet une approche histopathologique de nature. Le traitement de choix est la parotidectomie totale ou partielle. La radiothérapie peut être indiquée dans les formes malignes.Mots-clés : Tumeur, Parotide, Adénome pléomorphe, Maligne, Chirurgie

Optimization of the Cooling of a Thermoplastic Injection Mold

In injection molding processes for thermoplastic parts, the polymer solidification phase in the molding cavity has a strong influence on the quality of the shaped parts and also on the process cycle time. Reducing cycle time is one of the major concerns for plastic injection industries. As cooling phase presents the most critical phase to get quality and cycle time of the part, the application of additive manufacturing (AM) technologies has been overcoming the limitations of traditional cooling system design. AM enables the construction of conformal cooling channels for higher cooling uniformity due to its almost unlimited freedom of design that can fulfil the desired functions in injection molding process equipment. The analysis of the heat transfer during the phase of cooling allows the investigation of the optimal positioning of the cold sources and their intensities. In this paper, a systematic approach is used to replace conventional channels in an injection molding tool with conformal cooling channels. A simulation is used to develop a numerical model that describes the heat transfer and predicts the cycle time of both the optimal and conventional designs. Finally, a numerical comparison is made between traditional and conformal cooling to demonstrate the beneficial effect on reducing the manufacturing cycle and enhancing part quality

Comparative Analysis of Melt Pool Evolution in Selective Laser Melting of Inconel 625 and Inconel 718 Nickel-Based Superalloys

One of the key advantages of Additive Manufacturing is the versatility in working with a wide range of materials. Among these materials, Nickel-based superalloys have drawn great attention of specialists.  This study investigates the behavior of Inconel 625 and Inconel 718 during selective laser melting. While these alloys have many similarities, thus their distinct chemical compositions determine different responses to this new process, which the authors aimed to elucidate in this study. Numerical simulations using ANSYS Additive® software were conducted to compare the melt pool dimensions (depth and width) of Inconel 625 and Inconel 718. The results reveal that the material's thermal properties play a significant role in determining the melt pool geometry. The Inconel 718 consistently exhibited larger melt pool dimensions than Inconel 625. The findings highlight the importance of understanding the connection between the material properties and process parameters

Validation of a Novel Sensing Approach for Continuous Pavement Monitoring Using Full-Scale APT Testing

The objective of this paper is to present a novel approach for the continuous monitoring of pavement condition through the use of combined piezoelectric sensing and novel condition-based interpretation methods. The performance of the developed approach is validated for the detection of bottom-up fatigue cracking through full-scale accelerated pavement testing (APT). The innovative piezoelectric sensors are installed at the bottom of a thin 102 mm (4 in.) asphalt layer. The structure is then loaded until failure (up to 1 million loading cycles in this study). The condition-based approach, used in this work, does not rely on stain measurements and allows users to bypass the need for any structural or finite-element models. Instead, the data compression approach relies on variations in strain energy harvested by smart sensors to track changes in material and structural conditions. Falling weight deflectometer (FWD) measurements and visual inspections were used to validate the observations from the sensing system. The results in this paper present a first large-scale validation in pavement structures for a piezopowered sensing system combined with a new response-only based approach for data reduction and interpretation. The proposed data analysis method has demonstrated a very early detection capability compared to classical inspection methods, which unveils a huge potential for improved pavement monitoring

Facteurs predictifs de l’efficacite ablative de l’iode 131 dans les cancers differencies de la thyroïde

La prise en charge des cancers différenciés de la thyroïde (CDT) comporte souvent une radiothérapie métabolique à l’iode131 (IRA-thérapie). Le but de ce travail est d’évaluer le caractère prédictif des différents éléments anatomopathologiques, de la classification pTNM et de la stadification pronostique sur l’activité ablative requise d’iode131. Notre travail est une étude analytique rétrospective portant sur 275 cas de CDT ayant subit une thyroïdectomie totale. Tous ces patients ont eu une ou plusieurs activités ablatives. Nous avons cherché – au moyen d’une analyse statistique par test de Khi2 ou test Anova – toute corrélation entre les éléments de l’examen anatomopathologique de la tumeur, la classe pTNM, le stade pronostique correspondant d’une part  et l’efficacité de l’irathérapie ablative d’autre part. Dans notre série, une activité ablative plus élevée est nécessaire lorsque la taille du foyer tumoral dépasse les 6 cm (p=0,012), en cas de dépassement de la graisse péri thyroïdienne (

Investigating the Success and the Advantages of Using ERP System in KSA Context

Enterprise resource planning (ERP) is an important innovation, affecting the business world by generating improvements both tangible and intangible in large companies and small and medium enterprises (SME). This study focuses on the determinants of success and the advantages of the adoption of this technology. To address these points, a comprehensive literature survey was carried out in order to formulate an original research model for ERP success evaluation and provide a prospect for IT infrastructure and integration. The model, thus suggested and taken within the Kingdom of Saudi Arabia (KSA) context, examines in a systematic approach the relation between the ERP acceptance determinants, the effects of the process of ERP systems diffusion, and the impacts expected on organizational performance. Obtained results underline two key determinants of ERP projects success: First, the preponderance of information control and the improvement in the use of competences. The second factor is the quality of team projects, the definition of team’s mission, training, business processes reengineering, user acceptance, top management support and the selection of the ERP solution

Ресурсоэффективные системы в управлении и контроле: взгляд в будущее: сборник научных трудов VII Международной конференции школьников, студентов, аспирантов, молодых ученых, 8 -13 октября 2018 г., г. Томск

В сборнике представлены материалы VII Международной конференции школьников, студентов, аспирантов, молодых ученых "Ресурсоэффективные системы в управлении и контроле: взгляд в будущее". Более 500 авторов из 35 вузов, предприятий и научных исследовательских университетов России, ближнего и дальнего зарубежья представили тезисы своих докладов, в которых рассматриваются актуальные проблемы неразрушающего контроля и технической диагностики, внедрения систем менеджмента, качества образования, управления в современной экономике. Материалы предназначены для специалистов, преподавателей, аспирантов и студентов вузов, а также для всех интересующихся проблемами ресурсоэффективных технологий