8,648 research outputs found
1+1-dimensional p-wave superconductors from intersecting D-branes
In this work we explore 1+1 dimensional p-wave superconductors using the
probe D-brane construction. Specifically, we choose three intersecting D-brane
models: D1/D5, D2/D4 and D3/D3 systems. According to the dilaton running
behavior, we denote the former two systems as nonconformal models and the last
system as conformal. We find that all three models are qualitatively similar in
describing superconducting condensate as well as some basic features (such as
the gap formation and DC superconductivity) of superconducting conductivity.
There also exist some differences among the three models as far as the AC
conductivity is concerned. Specifically, for D3/D3 model there is no peak at
nonzero frequency for the imaginary part of the conductivity, which is present
in the nonconformal models; their asymptotic behaviors are different-for D1/D5
the real part of the AC conductivity approaches one at large frequency limit,
for D2/D4 it slowly goes to a certain nonzero constant smaller than one and for
D3/D3 it goes to zero. We find the profile of the AC conductivity for the D1/D5
system is very similar to that of higher dimensional p-wave superconductors.Comment: v2: matched with the published versio
Process reconstruction from incomplete and/or inconsistent data
We analyze how an action of a qubit channel (map) can be estimated from the
measured data that are incomplete or even inconsistent. That is, we consider
situations when measurement statistics is insufficient to determine consistent
probability distributions. As a consequence either the estimation
(reconstruction) of the channel completely fails or it results in an unphysical
channel (i.e., the corresponding map is not completely positive). We present a
regularization procedure that allows us to derive physically reasonable
estimates (approximations) of quantum channels. We illustrate our procedure on
specific examples and we show that the procedure can be also used for a
derivation of optimal approximations of operations that are forbidden by the
laws of quantum mechanics (e.g., the universal NOT gate).Comment: 9pages, 5 figure
Achievable efficiencies for probabilistically cloning the states
We present an example of quantum computational tasks whose performance is
enhanced if we distribute quantum information using quantum cloning.
Furthermore we give achievable efficiencies for probabilistic cloning the
quantum states used in implemented tasks for which cloning provides some
enhancement in performance.Comment: 9 pages, 8 figure
Case Studies of Strategic Alliances in Southeastern Beef Production
Three calf marketing and three commercial beef carcass strategic alliances were examined via case study to determine alliance structure and whether each addressed risk, transaction costs, capital availability, and other concerns. The alliances reduced transaction costs and increased information flow among segments, but did not specifically address risk.Livestock Production/Industries,
Case Studies of Strategic Alliances in U.S. Beef Production
Calf marketing, commercial beef carcass, and natural/implant-free beef strategic alliances were examined via case study to determine alliance structure and whether each addressed risk, transaction costs, capital availability, and other concerns. All alliances were structured differently through vertical or horizontal coordination, and each had been established within the past 12 years. Alliance administrators reported that an advantage to cow-calf producers was higher cattle prices received relative to producers outside the alliances. The alliances reduced transaction costs and increased information flow among segments. Alliances did not specifically address risk or increased access to capital for technology adoption or expansion purposes.cattle industry, industry structure, risk, strategic alliances, transaction costs, Agribusiness, Livestock Production/Industries,
Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors.
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide. Little is known about how niclosamide affects snails, including for Biomphalaria pfeifferi, the most important vector for Schistosoma mansoni in Africa. We used Illumina technology to explore how field-derived B. pfeifferi, either uninfected or harboring cercariae-producing S. mansoni sporocysts, respond to a sublethal treatment of niclosamide. This study afforded the opportunity to determine if snails respond differently to biotic or abiotic stressors, and if they reserve unique responses for when presented with both stressors in combination. We also examined how sporocysts respond when their snail host is treated with niclosamide.Principal findingsCercariae-producing sporocysts within snails treated with niclosamide express ~68% of the genes in the S. mansoni genome, as compared to 66% expressed by intramolluscan stages of S. mansoni in snails not treated with niclosamide. Niclosamide does not disable sporocysts nor does it seem to provoke from them distinctive responses associated with detoxifying a xenobiotic. For uninfected B. pfeifferi, niclosamide treatment alone increases expression of several features not up-regulated in infected snails including particular cytochrome p450s and heat shock proteins, glutathione-S-transferases, antimicrobial factors like LBP/BPI and protease inhibitors, and also provokes strong down regulation of proteases. Exposure of infected snails to niclosamide resulted in numerous up-regulated responses associated with apoptosis along with down-regulated ribosomal and defense functions, indicative of a distinctive, compromised state not achieved with either stimulus alone.Conclusions/significanceThis study helps define the transcriptomic responses of an important and under-studied schistosome vector to S. mansoni sporocysts, to niclosamide, and to both in combination. It suggests the response of S. mansoni sporocysts to niclosamide is minimal and not reflective of a distinct repertoire of genes to handle xenobiotics while in the snail host. It also offers new insights for how niclosamide affects snails
The in vivo transcriptome of Schistosoma mansoni in the prominent vector species Biomphalaria pfeifferi with supporting observations from Biomphalaria glabrata.
BackgroundThe full scope of the genes expressed by schistosomes during intramolluscan development has yet to be characterized. Understanding the gene products deployed by larval schistosomes in their snail hosts will provide insights into their establishment, maintenance, asexual reproduction, ability to castrate their hosts, and their prolific production of human-infective cercariae. Using the Illumina platform, the intramolluscan transcriptome of Schistosoma mansoni was investigated in field-derived specimens of the prominent vector species Biomphalaria pfeifferi at 1 and 3 days post infection (d) and from snails shedding cercariae. These S. mansoni samples were derived from the same snails used in our complementary B. pfeifferi transcriptomic study. We supplemented this view with microarray analyses of S. mansoni from B. glabrata at 2d, 4d, 8d, 16d, and 32d to highlight robust features of S. mansoni transcription, even when a different technique and vector species was used.Principal findingsTranscripts representing at least 7,740 (66%) of known S. mansoni genes were expressed during intramolluscan development, with the greatest number expressed in snails shedding cercariae. Many transcripts were constitutively expressed throughout development featuring membrane transporters, and metabolic enzymes involved in protein and nucleic acid synthesis and cell division. Several proteases and protease inhibitors were expressed at all stages, including some proteases usually associated with cercariae. Transcripts associated with G-protein coupled receptors, germ cell perpetuation, and stress responses and defense were well represented. We noted transcripts homologous to planarian anti-bacterial factors, several neural development or neuropeptide transcripts including neuropeptide Y, and receptors that may be associated with schistosome germinal cell maintenance that could also impact host reproduction. In at least one snail the presence of larvae of another digenean species (an amphistome) was associated with repressed S. mansoni transcriptional activity.Conclusions/significanceThis in vivo study, emphasizing field-derived snails and schistosomes, but supplemented with observations from a lab model, provides a distinct view from previous studies of development of cultured intramolluscan stages from lab-maintained organisms. We found many highly represented transcripts with suspected or unknown functions, with connection to intramolluscan development yet to be elucidated
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