Integrative model as a value creation tool in the customs administration system

The current system of customs administration provides a solution to complex economic and social problems. It is focused on the formation of value and consumer utility within the framework of the functions performed. In this regard, the quality of such a system is of particular importance. The article investigates the application of the value approach to the customs administration system. The paper carries out the analysis of the value chain formation. The study defines the approaches to the value assessment for each subject of the customs administration system. The paper proposes an integrative model that contributes to increasing the value of customs services in the system of service-oriented customs administration. The author draws conclusions about the role and significance of the value of each subject of the customs administration system in the formation of public value. The presented research is based on the concept of a holistic-evolutionary approach

Анализ влияния жевательной мускулатуры на череп экспериментального животного при наличии травмирующего/ изменяющего биомеханику мышцы фактора

Most authors recognize that the currently dominant scientific paradigm assumes that genomic rather than functional factors regulate (cause, control) the growth of cranial bones and cranial sutures. In contrast, the authors of this article offer some clarifications to address some unintentional conceptual misconceptions, based primarily on an extensive review of the relevant current literature and their own experience. This article describes the increased modulation of mechanotransduction produced by skeletal muscle activity, to which bone cells respond maximally. The authors describe the actual chain of events that influences the stimulation of bone cell growth. This influence makes it possible to propose a means of controlling these processes and developing new correction methods, including suppression of phenotypic expression. The authors present the results of a study of the effect of mechanical loading of the masticatory muscles with a continuous stretching stimulus to increase the width of extension of the sagittal suture of the experimental animal in vivo. The methodology is described, and objective instrumental control data are presented. The results of statistical processing are also presented. The authors give empirical data in this paper. These experiments prove that chewing load is one of the primary stimuli that generate craniofacial variations, affecting the structure of the cranial suture. The authors conducted the experimental part of the research at the Vivarium of Conventional Animals Collaborative Center of the Federal Research Center of the Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences.Признавая, что доминирующая в настоящее время научная парадигма предполагает, что геномные, а не функциональные факторы регулируют (вызывают, контролируют) рост костей черепа и черепных швов, основываясь, прежде всего, на обширном обзоре соответствующей современной литературы и собственном опыте, авторы предлагают ряд уточнений, направленных на устранение некоторых непреднамеренных концептуальных заблуждений. В данной статье описывается процесс повышения модуляции механотрансдукции, продуцируемый мышечной активностью скелетных мышц, на которые максимально реагируют костные клетки. Авторами описанафактическаяцепь событий, оказывающая влияниена стимуляциюроста костных клеток, что позволяет предложить средство контроля данных процессов, разрабатывать новые методики коррекции, включая подавление фенотипической экспрессии. В статье представлены результаты исследования влияния механической нагрузки жевательных мышц с непрерывным стимулом растяжения в направлении увеличения ширины / растяжения сагиттального шва экспериментального животного in vivo. Описана методика и представлены данные объективного инструментального контроля, а также результаты, полученные в результате статистической обработки. Авторы в данной работе представляют экспериментальные доказательства того, что жевательная нагрузка является одним из основных стимулов, который генерирует черепно-лицевые вариации, влияя на структуру черепного шва. Экспериментальная часть исследований проводилась на базе Центра коллективного пользования «Виварий конвенциональных животных» Федерального исследовательского центра Институт цитологии и генетики Сибирского отделения Российской академии наук

Integrative model of customs and foreign economic activities as element of the system of environmental economics

Development of the theory assumes existence in its basis of an idealized object - theoretical model. Creation of such object - a necessary stage of creation of any theory, including theories of customs management. Customs management represents the theory of management of customs affairs - the customs organizations, processes (functions, procedures, operations), technologies, resources (personnel, information, etc.), services. © The Authors, published by EDP Sciences, 2019

Comprehensive Neonatal Nursing: A Physiologic Perspective (6th ed.)

Dorothy Vittner (with Jacqueline M. McGrath) is a contributing author, Family: Essential Partners in Care , Chapter 27 pp.753-784. Book description: The sixth edition of this acclaimed neonatal nursing text is completely updated to encompass the most current research findings and strategies for providing cost-effective and evidence-based care. It continues to address neonatal care from a physiologic and pathophysiologic perspective, with a major emphasis on nursing management at the bedside and advanced practice level. It examines each neonatal body system and describes evidence-based interventions that assist in understanding the ‘why’ behind various clinical presentations. Integrative management is threaded throughout the text along with extensive research findings to support practice strategies and rationales for sound clinical decision-making. Case studies, evidence-based practice boxes, QSEN competencies, and online resources help to amplify and reinforce content.https://digitalcommons.fairfield.edu/nursing-books/1087/thumbnail.jp

CHARACTERSTICS OF IMMUNE EFFECT OF BEMITHYL IN CHRONIC HEPATITIS

Abstract. Introduction of bemithyl into combined therapy of patients suffering chronic hepatitis allows toachieve a noticeable hepatoprotective effect. Apparently it is realized due to direct hepatotropic influence as well as through immunomodulatory action of the preparation directed at cellular immunity. At the same time, immunotropic action of bemithyl can be characterized as immunomodulatory one, which is confirmed by stimulation of T–cell immunity with some suppression of B–section and humoral immunity. An important factor of the immunotropic action of the drug is the absence of autoimmunization phenomena. Influence of bemithyl on macrophages section manifested by the decrease of liver tissue infiltration and simultaneous increase of blood monocyte count. At the same time, initial oxygen–dependent microbicidal activity of macrophages decreased a little, but stimulated indices increased. (Med. Immunol., 2005, vol.7, № 1, pp 93599