539 research outputs found
Electric Switching of the Charge-Density-Wave and Normal Metallic Phases in Tantalum Disulfide Thin-Film Devices
We report on switching among three charge-density-wave phases - commensurate,
nearly commensurate, incommensurate - and the high-temperature normal metallic
phase in thin-film 1T-TaS2 devices induced by application of an in-plane
electric field. The electric switching among all phases has been achieved over
a wide temperature range, from 77 K to 400 K. The low-frequency electronic
noise spectroscopy has been used as an effective tool for monitoring the
transitions, particularly the switching from the incommensurate
charge-density-wave phase to the normal metal phase. The noise spectral density
exhibits sharp increases at the phase transition points, which correspond to
the step-like changes in resistivity. Assignment of the phases is consistent
with low-field resistivity measurements over the temperature range from 77 K to
600 K. Analysis of the experimental data and calculations of heat dissipation
suggest that Joule heating plays a dominant role in the electric-field induced
transitions in the tested 1T-TaS2 devices on Si/SiO2 substrates. The
possibility of electrical switching among four different phases of 1T-TaS2 is a
promising step toward nanoscale device applications. The results also
demonstrate the potential of noise spectroscopy for investigating and
identifying phase transitions in materials.Comment: 32 pages, 7 figure
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NPAS4 recruits CCK basket cell synapses and enhances cannabinoid-sensitive inhibition in the mouse hippocampus.
Experience-dependent expression of immediate-early gene transcription factors (IEG-TFs) can transiently change the transcriptome of active neurons and initiate persistent changes in cellular function. However, the impact of IEG-TFs on circuit connectivity and function is poorly understood. We investigate the specificity with which the IEG-TF NPAS4 governs experience-dependent changes in inhibitory synaptic input onto CA1 pyramidal neurons (PNs). We show that novel sensory experience selectively enhances somatic inhibition mediated by cholecystokinin-expressing basket cells (CCKBCs) in an NPAS4-dependent manner. NPAS4 specifically increases the number of synapses made onto PNs by individual CCKBCs without altering synaptic properties. Additionally, we find that sensory experience-driven NPAS4 expression enhances depolarization-induced suppression of inhibition (DSI), a short-term form of cannabinoid-mediated plasticity expressed at CCKBC synapses. Our results indicate that CCKBC inputs are a major target of the NPAS4-dependent transcriptional program in PNs and that NPAS4 is an important regulator of plasticity mediated by endogenous cannabinoids
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