Impaired path integration in mice with disrupted grid cell firing

Path integration (PI) is a highly conserved, self-motion-based navigation strategy. Since the discovery of grid cells in the medial entorhinal cortex, neurophysiological data and computational models have suggested that these neurons serve PI. However, more direct empirical evidence supporting this hypothesis has been missing due to a lack of selective manipulations of grid cell activity and suitable behavioral assessments. Here we report that selective disruption of grid cell activity in mice can be achieved by removing NMDA glutamate receptors from the retro-hippocampal region and that disrupted grid cell firing accounts for impaired PI performance. Notably, the genetic manipulation did not affect the activity of other spatially selective cells in the medial entorhinal cortex and the hippocampus. By directly linking grid cell activity to PI, these results contribute to a better understanding of how grid cells support navigation and spatial memory

Results for Permutation Flowshop Scheduling Problems

This repository contains all the problem sets for Permutation Flowshop Scheduling, by Carlier, Heller, Lahiri, Reeves and Taillard. All problems are accompanied by their solutions in the form of permutations, in a format corresponding to Matlab data files (.mat), obtained with an evolutionary algorithm. The "Verification of the result" folder includes the program 'solutionCheck.m' for checking the correctness of the solution given by the permutations included in the other folders.In the folder 'Lower Bound', there is a pdf file 'LB correction' where you can find an important remark concerning LB calculation with E. Taillard's formulas. The folder contains a Matlab code for Lower Bound calculation, according to the this remark

Results for Permutation Flowshop Scheduling Problems

This repository contains all the problem sets for Permutation Flowshop Scheduling, by Carlier, Heller, Lahiri, Reeves and Taillard. All problems are accompanied by their solutions in the form of permutations, in a format corresponding to Matlab data files (.mat), obtained with an evolutionary algorithm. The "Verification of the result" folder includes the program 'solutionCheck.m' for checking the correctness of the solution given by the permutations included in the other folders.In the folder 'Lower Bound', there is a pdf file 'LB correction' where you can find an important remark concerning LB calculation with E. Taillard's formulas. The folder contains a Matlab code for Lower Bound calculation, according to the this remark.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV