Event related potentials (ERP's) in psychiatry

International audienceno abstrac

Clinical neurophysiology in psychiatry: I - Techniques, vocabularies and indications of conventional electroencephalogram

International audienceno abstrac

Toward a transdiagnostic tool to evaluate depressive symptoms across mental disorders: Validation of the Calgary depression rating scale in patients with major depressive disorder

International audienc

Peripheral inflammation is associated with brain SPECT perfusion changes in schizophrenia

International audienc

Does sensory gating have a protective effect against hallucinatory ă behavior in schizophrenia?

International audienceno abstrac

Does sensory gating have a protective effect against hallucinatory behavior in schizophrenia?

International audienceno abstrac

SENSORY GATING DEFICITS AND IMPAIRED QUALITY OF LIFE IN PATIENTS WITH SCHIZOPHRENIA: A PRELIMINARY STUDY

Background: New determinants of quality of life in schizophrenia need to be identified. As sensory gating deficit is core impairment in schizophrenia, the present study hypothesized that sensory gating deficit is a determinant of impaired quality of life in schizophrenia. This study therefore investigated the relationship between sensory gating deficit and quality of life in patients with schizophrenia after adjusting for key confounding factors. Subjects and methods: Sensory gating was assessed with the auditory event-related potential method by measuring P50 amplitude changes in a double-click conditioning-testing procedure, perceptual impairments related to sensory gating deficit was assessed with the SGI questionnaire and quality of life was assessed with the SQoL 18 questionnaire in 39 patients with schizophrenia. Results: Patients with sensory gating deficit (n=14) had a lower subjective quality of life on the psychological well-being dimension evaluated with SQoL 18 questionnaire (p=0.008) compared to those without it (n=25). This result remained significant (B=-0.45, Wald=4.84, p=0.02) after taking into account 7 potential confounding factors (gender, age, level of education, duration of disorder, positive symptoms, depressive symptoms and anxiety symptoms). Poorer psychological well-being was related to a higher score on the SGI (rho=-0.40, p=0.01), in particular on the Distractibility dimension (rho=-0.47, p=0.001). Conclusions: These findings suggest that sensory gating deficit may be a determinant of impaired quality of life in schizophrenia. Further studies are needed to address the causal relationship between sensory gating deficit, perceptual impairments, attentional deficit and impaired quality of life in schizophrenia in order to act more efficiently on the quality of life of patients with this disorder

Natural speech comprehension in bipolar disorders: An event-related brain potential study among manic patients

International audienceno abstrac

Association of metabolic syndrome with sensory gating deficits in patients with chronic schizophrenia

International audienceno abstrac

Elevated C-reactive protein is associated with sensory gating deficit in schizophrenia

International audienceno abstrac