2,695 research outputs found
How fast is a twisted photon?
Recent measurements have highlighted that spatially shaped photons travel
slower than c, the speed of monochromatic, plane waves in vacuum. Here we
investigate the intrinsic delay introduced by `twisting' a photon, i.e. by
introducing orbital angular momentum (OAM). In order to do this we use a
Hong-Ou-Mandel interferometer to measure the change in delay of single photons
when we introduce OAM on a ring-shaped beam that is imaged through a focusing
telescope. Our findings show that when all other parameters are held constant
the addition of OAM reduces the delay (accelerates) with respect to the same
beam with no OAM. We support our results using a theoretical method to
calculate the group velocity and gain an intuitive understanding of the
measured OAM acceleration by considering a geometrical ray-tracing approach.Comment: 5 pages, 4 figure
Coherent absorption of N00N states
Recent results in deeply subwavelength thickness films demonstrate coherent control and logical gate operations with both classical and single-photon light sources. However, quantum processing and devices typically involve more than one photon and nontrivial input quantum states. Here we experimentally investigate two-photon N00N state coherent absorption in a multilayer graphene film. Depending on the N00N state input phase, it is possible to selectively choose between single- or two-photon absorption of the input state in the graphene film. These results demonstrate that coherent absorption in the quantum regime exhibits unique features, opening up applications in multiphoton spectroscopy and imaging
Oral ezatiostat HCl (Telintra®, TLK199) and Idiopathic Chronic Neutropenia (ICN): a case report of complete response of a patient with G-CSF resistant ICN following treatment with ezatiostat, a glutathione S-transferase P1-1 (GSTP1-1) inhibitor
Idiopathic chronic neutropenia (ICN) describes a heterogeneous group of hematologic diseases characterized by low circulating neutrophil levels often associated with recurrent fevers, chronic mucosal inflammation, and severe systemic infections. The severity and risk of complications, including serious infections, are inversely proportional to the absolute neutrophil count (ANC), with the greatest problems occurring in patients with an ANC of less than 0.5 × 109/L. This case report describes a 64-year-old female with longstanding rheumatoid arthritis who subsequently developed ICN with frequent episodes of sepsis requiring hospitalization and prolonged courses of antibiotics over a 4-year period. She was treated with granulocyte colony stimulating factors (G-CSF) but had a delayed, highly variable, and volatile response. She was enrolled in a clinical trial evaluating the oral investigational agent ezatiostat. Ezatiostat, a glutathione S-transferase P1-1 inhibitor, activates Jun kinase, promoting the growth and maturation of hematopoietic progenitor stem cells. She responded by the end of the first month of treatment with stabilization of her ANC (despite tapering and then stopping G-CSF), clearing of fever, and healing of areas of infection. This ANC response to ezatiostat treatment has now been sustained for over 8 months and continues. These results suggest potential roles for ezatiostat in the treatment of patients with ICN who are not responsive to G-CSF, as an oral therapy alternative, or as an adjunct to G-CSF, and further studies are warranted
Metasurface imaging with entangled photons
Plasmonics and metamaterials have recently been shown to allow the control
and interaction with non-classical states of light, a rather counterintuitive
finding given the high losses typically encountered in these systems. Here, we
demonstrate a range of functionalities that are allowed with correlated and
entangled photons that are used to illuminate multiple, overlaid patterns on
plasmonic metasurfaces. Correlated photons allow to nonlocally determine the
pattern that is imaged or, alternatively to un-scramble an image that is
otherwise blurred. Entangled photons allow a more important functionality
whereby the images imprinted on the metasurface are individually visible only
when illuminated with one of the entangled photons. Correlated single photon
imaging of functional metasurfaces could therefore promise advances towards the
use of nanostructured subwavelength thin devices in quantum information
protocols.Comment: 8 page
Two-magnon Raman scattering in insulating cuprates: Modifications of the effective Raman operator
Calculations of Raman scattering intensities in spin 1/2 square-lattice
Heisenberg model, using the Fleury-Loudon-Elliott theory, have so far been
unable to describe the broad line shape and asymmetry of the two magnon peak
found experimentally in the cuprate materials. Even more notably, the
polarization selection rules are violated with respect to the
Fleury-Loudon-Elliott theory. There is comparable scattering in and
geometries, whereas the theory would predict scattering in only
geometry. We review various suggestions for this discrepency and
suggest that at least part of the problem can be addressed by modifying the
effective Raman Hamiltonian, allowing for two-magnon states with arbitrary
total momentum. Such an approach based on the Sawatzsky-Lorenzana theory of
optical absorption assumes an important role of phonons as momentum sinks. It
leaves the low energy physics of the Heisenberg model unchanged but
substantially alters the Raman line-shape and selection rules, bringing the
results closer to experiments.Comment: 7 pages, 6 figures, revtex. Contains some minor revisions from
previous versio
Coherent metamaterial absorption of two-photon states with 40% efficiency
Multiphoton absorption processes have a nonlinear dependence on the amplitude of the incident optical field, i.e., the number of photons. However, multiphoton absorption is generally weak and multiphoton events occur with extremely low probability. Consequently, it is extremely challenging to engineer quantum nonlinear devices that operate at the single photon level and the majority of quantum technologies have to rely on single photon interactions. Here we demonstrate experimentally and theoretically that exploiting coherent absorption of
N
=
2
NOON states makes it possible to enhance the number of two-photon states that are absorbed by at most a factor of 2 with respect to a linear absorption process. An absorbing metasurface placed inside a Sagnac-style interferometer into which we inject an
N
=
2
NOON state, exhibits two-photon absorption with
40.5
%
efficiency, close to the theoretical maximum. This high probability of simultaneous absorption of two photons holds the promise for applications in fields that require multiphoton upconversion but are hindered by high peak intensities
Commentary: Essential Programs and Services Model
To further discussion about the Essential Programs and Services (EPS) model for funding public education in Maine, Maine Policy Review asked eight superintendents—representing districts across the state— to provide their views. We also asked each to discuss the needs of his district and whether additional state policy options were necessary to tackle the most pressing issues. The districts represented by these superintendents are a cross section of urban and rural high-receivers and low-receivers. Still, several commonalities emerge: the need for a state commitment that does not wax and wane with the business cycle; the urgency of professional development for new and experienced teachers; and, the importance of linking student outcomes with student assessment measures and student funding. In short, EPS is not seen as a solution to the state’s ongoing debate over public-education funding, but is recognized as a necessary first step
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