228 research outputs found
The principle of antagonism ensures protein targeting specificity at the endoplasmic reticulum
Crystal structure of a TAF1-TAF7 complex in human transcription factor IID reveals a promoter binding module
N=1 Human Study in Clinical Neurosciences: Genomics Guided Medicine and Deep Brain Stimulation
(Hyper)tension release by N-terminal acetylation / Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway
Association of Protein Biogenesis Factors at the Yeast Ribosomal Tunnel Exit Is Affected by the Translational Status and Nascent Polypeptide Sequence
A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress
Guest post: Time to bring human genome sequencing into the clinic
Gholson Lyon is a physician-scientist currently working at the Utah Foundation for Biomedical Research and the Center for Applied Genomics at Children’s Hospital of Philadelphia. He will be starting as an assistant professor in human genetics at Cold Spring Harbor Laboratory next month. I asked him to write this guest post to provide some personal context to his thought-provoking commentary in Nature (subscription required) on returning genetic findings to research subjects. [DM
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