7 research outputs found
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk
- Author
- Aalfs C.M. (Cora)
- Adenis C. (Claude)
- Adlard J.W. (Julian)
- Agata S. (Simona)
- Agnarsson B.A. (Bjarni)
- AittomÀki K. (Kristiina)
- Andersen M.K. (Mette)
- Andrulis I.L. (Irene)
- Angelakos M. (Maggie)
- Antoniou A.C. (Antonis)
- Ardern-Jones A. (Audrey)
- Ardnor C.E. (Christina Edwinsdotter)
- Arnold N. (Norbert)
- Arun B.K. (Banu)
- Arver B. (Brita Wasteson)
- Asperen C.J. (Christi) van
- Attard V. (Virginia)
- Ausems M.G.E.M. (Margreet)
- Bacot F. (Francois)
- Bae-Jump V.L. (Victoria L.)
- Balmana J. (Judith)
- Bancroft E.K. (Elizabeth)
- Bardsley C. (Cathryn)
- Barjhoux L. (Laure)
- Barkardottir R.B. (Rosa)
- Barouk-Simonet E. (Emmanuelle)
- Barrowdale D. (Daniel)
- Barton D.E. (David)
- Barwell J. (Julian)
- Beattie M.S. (Mary)
- Belotti M. (Muriel)
- BenĂtez J. (Javier)
- Berlin C. (Cheryl)
- Berthet P. (Pascaline)
- Bignon Y.-J. (Yves-Jean)
- Bignon Y.-J. (Yves-Jean)
- Blanco I. (Ignacio)
- Blank S.V. (Stephanie)
- Blok M.J. (Marinus)
- Bock G.H. (Geertruida) de
- Bonadona V. (Valérie)
- Bonnani B. (Bernardo)
- Bonnet F. (Françoise)
- Borg Ă . (Ă ke)
- Bourdon V. (Violaine)
- Bradshaw N. (Nicola)
- Brady A.F. (Angela)
- Bressac-de Paillerets B. (Brigitte)
- Brewer C. (C.)
- Brewer C. (Carole)
- Brice G. (Glen)
- Bronner M. (Myriam)
- Brunet J. (Joan)
- Bubien V. (Virginie)
- Buecher B. (Bruno)
- Bustinza G.B.
- Buys S.S. (Saundra)
- Caldes T. (Trinidad)
- Calender A. (Alain)
- Caligo M.A. (Maria)
- Campbell I. (Ian)
- Caron O. (Olivier)
- Castera L. (Laurent)
- Castro E. (Elena)
- Chan S. (Salina)
- Chenevix-Trench G. (Georgia)
- Chiquette J. (Jocelyne)
- Chung W.K. (Wendy)
- Claber O. (Oonagh)
- Claes K. (Kathleen)
- Cohn D.E. (David)
- Colas C. (Chrystelle)
- Cole T.J. (Trevor)
- Collier R. (Rebecca)
- Collée J.M. (Margriet)
- Cook J. (Jackie)
- Coron F. (Fanny)
- Couch F.J. (Fergus)
- Coulet F. (Florence)
- Coupier I. (Isabelle)
- Crawford G. (Gabe)
- Cronenburg T.C.T.E.F. van
- Cunningham J. (Jane)
- Daly M.B. (Mary)
- Damiola F. (Francesca)
- Damiola F. (Francesca)
- Davidson R. (Rosemarie)
- Deissler H. (Helmut)
- Delnatte C.D. (Capucine)
- Demange L. (Liliane)
- Dennis J. (Joe)
- Deurzen C.H.M. (Carolien) van
- Devilee P. (Peter)
- Devilee P. (Peter)
- Dicks E. (Ed)
- Diez O. (Orland)
- Ding Y.C. (Yuan)
- Dite G.S. (Gillian)
- Ditsch N. (Nina)
- Domchek S.M. (Susan)
- Donaldson A. (Alan)
- Dorfling C.M. (Cecelia)
- Dorkins H. (Huw)
- Douglas F. (Fiona)
- Douglas F. (Fiona)
- Dreyfus H. (HĂ©lĂšne)
- Drummond S. (Sarah)
- Duncan A. (Alexis)
- Dunning A.M. (Alison)
- Durda K. (Katarzyna)
- Durell S. (Sarah)
- DurĂĄn M. (Mercedes)
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- Ehrencrona H. (Hans)
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- Eisinger F. (François)
- Ejlertsen B. (Bent)
- Ellis I.O. (Ian)
- Ellis S. (Steve)
- Ellis S.D. (Steve)
- Emanuelsson M. (Monica)
- Engel C. (Christoph)
- Engert S. (Stefanie)
- Evans D.G. (Gareth)
- Ewart-Toland A. (Amanda)
- Faivre L. (Laurence)
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- Ferrer S.F.
- Fineberg E. (Elena)
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- Fink-Retter A. (Anneliese)
- Foretova L. (Lenka)
- Fournier J. (Joëlle)
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- Frenay M. (Marc)
- Fricker J.P. (Jean Pierre)
- Friebel M.O.W. (Mark )
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- Friedman E. (Eitan)
- Frost D. (Debra)
- Gadzicki D. (Dorothea)
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- Garber J.
- Gaudet M.M. (Mia)
- Gauthier-Villars M. (Marion)
- Gehrig P.A. (Paola A.)
- Gerdes A-M. (Anne-Marie)
- Gibson S. (Sarah)
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- Gladieff L. (Laurence)
- Glendon G. (Gord)
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- Goff S. (Sheila)
- Goldgar D. (David)
- Gomez Garcia E.B. (Encarna)
- Goodman S. (Selina)
- Greene M.H. (Mark)
- Gregory H. (Helen)
- Gronwald J. (Jacek)
- Gschwantler-Kaulich D. (Daphne)
- Guimbaud R. (Rosine)
- GĂłmez GarcĂa E.B. (Encarna)
- Hall A.S. (Alistair)
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- Hamann U. (Ute)
- Handallou S. (Sandrine)
- Hansen T.V.O. (Thomas)
- Haque E. (Eshika)
- Harbst K. (Katja)
- Hardouin A. (AgnĂšs)
- hardouin A. (AgnĂšs)
- Hart S. (Stewart)
- Healey S. (Sue)
- Henriksson K. (Karin)
- Herzog J. (Josef)
- Hodgson S.V. (Shirley)
- Hoffman J. (Jonathan)
- Hogervorst F.B.L. (Frans)
- Hooning M.J. (Maartje)
- Houdayer C. (Claude)
- Houghton C. (Catherine)
- Houlston R. (Richard)
- Hout A.H. (Annemarie) van der
- Hoya M. (Miguel) de La
- Huo D. (Dezheng)
- Huzarski T. (Tomasz)
- Imyanitov E.N. (Evgeny)
- Izatt L. (Louise)
- Izatt L. (Louise)
- Jacobs C. (Chris)
- Jakubowska A. (Anna)
- James M. (Margaret)
- James P.A. (Paul )
- Janavicius R. (Ramunas)
- Jaworska K. (Katarzyna)
- Jeffers L. (Lisa)
- Jensen U.B.
- Jernström H. (H.)
- Jobson I. (Irene)
- John E.M. (Esther)
- JĂžnson L. (Lars)
- Karlan B.Y. (Beth)
- Karlsson P. (Per)
- Kast K. (Karin)
- Kauff N. (Noah)
- Kaufman B. (Bella)
- Kennedy M.J. (John)
- Kets C.M. (Marleen)
- Kientz C. (Caroline)
- Killick S.R.
- Kivuva E. (Emma)
- Kohut K. (Kelly)
- Kosel M. (Matthew)
- Kristoffersson U. (Ulf)
- Kruse T.A. (Torben)
- Kuchenbaecker K.B. (Karoline)
- Kulkarni A. (Anjana)
- Kwong A. (Ava)
- Laitman Y. (Yael)
- Lalloo F. (Fiona)
- Lange J.L. (J.) de
- Langman C. (Caroline)
- Lasa A. (Adriana)
- Lasset C. (Christine)
- Lebrun M. (Marine)
- Lee A. (Andrew)
- Leeuwen F.E. (Flora) van
- Leeuwen F.E. (Flora) van
- Lehmann A. (Anna)
- Lejbkowicz F. (Flavio)
- Leroux D. (Dominique)
- Lester K.J. (Kathryn)
- Lidereau R. (Rosette)
- Liedgren S. (Sigrun)
- Ligtenberg M.J. (Marjolijn)
- Liljegren A. (Annelie)
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- Loman N. (Niklas)
- Longmuir M. (Mark)
- Longy M. (Michel)
- Loud J.T. (Jennifer)
- Lu K.H. (Karen)
- Lubinski J. (Jan)
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- Luijt R.B. (Rob) van der
- Lynch H. (Henry)
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- LĂ©one M. (MĂ©lanie)
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- Mulligan A.M. (Anna Marie)
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- Murray A. (Anna)
- Narod S. (Steven)
- Nathanson K.L. (Katherine)
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- Nielsen F.C. (Finn)
- Noguchi T. (Tetsuro)
- Nogues C. (Catherine)
- Nordling M. (Margareta)
- Offit K. (Kenneth)
- Olah E.
- Olopade O.I. (Olofunmilayo)
- Olsson H.
- Olswold C. (Curtis)
- Ong K.-R. (Kai-Ren)
- Oosterwijk J.C. (Jan)
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- Os T.A.M. (Theo) van
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- Ozcelik H. (Hilmi)
- Page E. (Elizabeth)
- Pankratz V.S. (Shane)
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- Pastinen T. (Tomi)
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- Pauw A. (Antoine) de
- Pedersen I.S. (Inge Sokilde)
- Peissel B. (Bernard)
- Pensotti V. (Valeria)
- Peock S. (Susan)
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- Peyrat J.-P.
- Peysselon M. (Magalie)
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- Quarrell O. (Oliver)
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- Rebischung C. (Christine)
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- Rensburg E.J. (Elizabeth) van
- Rhiem K. (Kerstin)
- Robson M. (Mark)
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- Rookus M.A. (M.)
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- Rosenquist R. (R.)
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- Vijai J. (Joseph)
- Vincent D. (Daniel)
- Volorio S. (Sara)
- VĂ©nat-Bouvet L. (Laurence)
- Wachenfeldt A. (Anna) von
- Waisfisz Q. (Quinten)
- Walker L.J. (Lisa)
- Walsh C.S. (Christine)
- Wang C. (Chen)
- Wang X. (Xianshu)
- Wapenschmidt B. (Barbara)
- Watt C. (Catherine)
- Weaver J. (JoEllen)
- Weber B.H.F. (Bernhard)
- Weitzel J.N. (Jeffrey)
- Wiggins J. (Jennifer)
- Wijnen J.T. (Juul)
- Wijnen J.T. (Juul)
- Winchester L. (Lizzie)
- Yannoukakos D. (Drakoulis)
- ZĆowocka-PerĆowska E. (Elzbieta)
- Ăfverholm A. (Anna)
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 15/04/2013
- Field of study
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with ovarian cancer), with a further replication in an additional sample of 2,646 BRCA1 carriers. We identified a novel breast cancer risk modifier locus at 1q32 for BRCA1 carriers (rs2290854, P = 2.7Ă10-8, HR = 1.14, 95% CI: 1.09-1.20). In addition, we identified two novel ovarian cancer risk modifier loci: 17q21.31 (rs17631303, P = 1.4Ă10-8, HR = 1.27, 95% CI: 1.17-1.38) and 4q32.3 (rs4691139, P = 3.4Ă10-8, HR = 1.20, 95% CI: 1.17-1.38). The 4q32.3 locus was not associated with ovarian cancer risk in the general population or BRCA2 carriers, suggesting a BRCA1-specific associat
Response of lettuce to Trichoderma treatment
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Income non-reporting: implications for health inequalities research
- Author
- Australian Bureau of Statistics
- Australian Bureau of Statistics
- Backlund E.
- Berkman L.F.
- Blaxter M.
- Brick J.M.
- Catania J.A.
- Colsher P.L.
- Craig C.S.
- Davis P.B.
- Dengler R.
- ED De Leeuw
- Etter J.F.
- Fein O.
- Feinstein J.S.
- G. Turrell
- Guadagnoli E.
- Hippler H.J.
- House J.S.
- Jordan L.A.
- Kaplan G.A.
- Kormendi E.
- Liberatos P.
- Little R.J.A.
- Locander W.B.
- Lynch J.W.
- Lynch J.W.
- Martelin T.
- Martin-Matthews A.
- Mathers C.
- McDonough P.
- Melton L.J.
- Messmer D.J.
- Pappas G.
- Prendergast M.J.
- Saunders P.
- Sheikh K.
- Siemiatycki J.
- Slymen D.J.
- Stokes M.E.
- Sudman S.
- Turrell G.
- Vestbo J.
- Wright J.D.
- Publication venue
- 'BMJ'
- Publication date
- Field of study
Baseband Modulation Codes
- Author
- ] J.M. Griffiths
- A
- A Croisier
- A Gabor
- A Gallopoulos
- A Lender
- A Patel
- B Marcus
- B Marcus
- BH Marcus
- D Palmer
- D.A
- DB Waters
- E Jorgensen
- EA Lee
- ED Sunde
- G
- G
- G Jacoby
- G.F
- GL Cariolaro
- H
- H-W Wong-Lam
- H.D.L
- I.L
- IJ Fair
- J.J
- J.L
- J.W.M
- JB Buchner
- JE Savage
- JK Wolf
- JN Franklin
- JR Pierce
- JW Rae
- JWM Bergmans
- JWM Bergmans
- JWM Bergmans
- K.W
- K.W
- KA Schouhamer
- KA Schouhamer
- KA Schouhamer
- KA Schouhamer
- KA Schouhamer
- KA Schouhamer
- KA Schouhamer
- KJ Kerpez
- KJ Kerpez
- KW Cattermole
- L.J
- L.J
- LJ Fredrickson
- M Cohn
- M Hecht
- MG Pelchat
- MK Simon
- MR Aaron
- NQ Duc
- NQ Duc
- P Kabal
- P.A
- P.H
- PA Franaszek
- PA Franaszek
- PA Franaszek
- PA Franaszek
- PA Franaszek
- PH Siegel
- PJ Gerwen
- PJ Gerwen
- R Blahut
- R Blahut
- R Brush
- R Karabed
- R Wood
- R Ziemer
- R.F
- R.O
- R.W
- RC Schneider
- RD Cideciyan
- RJ Mceliece
- RL Adler
- RM Brooks
- RT Lynch
- RW Lucky
- S Yoshida
- SW Golomb
- TM Chien
- W Peterson
- Y Okamoto
- Y Takasaki
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1996
- Field of study
Mechanical ventilation in patients with cardiogenic pulmonary edema : a sub-analysis of the LUNG SAFE study
- Author
- Abad R.D.
- Abe Toshikazu
- Abroug Fekri
- Adams J.C.
- Adamsson R.O.
- Adolfsson A.
- Aguilar R.Z.
- Aguirre J.S.
- Aguirre-Bermeo Hernan
- Aisa T.M.
- Aisiku Imoigele P.
- Ajetunmobi O.O.
- Aker M.
- Akyol O.O.
- Al Dorzi H.M.
- Albaiceta G.M.
- Albaiceta Guillermo M.
- Albarrak M.M.
- Albiero D.
- Alda R.S.
- Alejandro Risso V.
- Alexander P.
- Alfonso A.A.T.
- Algaba Ă.
- Aliaga Felipe A.
- Alisasis A.U.
- AlJabbary A.S.
- Allan R.M.
- Allue R.M.
- Almekhlafi G.
- Alonso J.G.
- Altaf W.
- Alvarez A.M.
- Alvarez Javier
- Amado-RodrĂguez Laura
- Amin Pravin
- Amir F.
- Amor M.
- An Youzhong
- Andersen F.H.
- Andoh K.
- Andruszkiewicz P.
- Aneman Anders
- Antonelli M.M.
- AntĂŽnio Ana Carolina P.
- Aoki N.
- Appelberg H.
- Arabi Yaasen.
- Araujo A.M.
- Arizmendi A.
- Arnal J.M.
- Artiga M.J.D.
- Artigas A.
- Ascoli Aline
- Avila L.E.
- Azad Raman
- Azevedo Luciano Cesar
- Baboi L.
- Badie J.C.
- Bailey Irene M.
- Bailey M.B.
- Bajwa Ed
- Balkhi H.
- Baltus T.
- BannerGoodspeed V.M.
- Barberet G.
- Baro R.M.
- Baronia A.K.
- Barratt-Due A.
- Barros F.M.
- Barros N.C.
- Batra H.
- Battle C.E.
- Bauer P.R.
- Beck E.
- Beck O.
- Bedreag O.H.
- Beegle S.H.
- Beitler J.R.
- Beloncle Francois
- Benslama A.
- Beraldo Daniel O.
- Berghe Caroline
- Berkelmans F.
- Besset S.L.
- Bettini Lisandro R.
- Beuret P.
- Bezzi Marco G.
- Bhardwaj V.K.
- Bhowmick K.
- Biehler J.
- Bigot C.
- Bihari Shailesh
- BinHJAbul Wahab Ahmad Yazid
- Biondi Rodrigo S.
- Biscione R.R.
- Bisso Mariano Carboni
- Black C.S.
- Blakeman T.C.
- Blanco J.
- Bolon S.
- Borello Silvina A.
- Borotto E.E.
- Botteri M.
- Bouchoucha S.
- Boukhazna M.
- Bouw M.J.
- Boyd O.
- Bramall J.
- Braschi A.
- Brazzi L.
- Breen D.M.
- Briquet A.
- Brito V.A.
- Brizuela Matias
- Brochard L.
- Broman L.M.
- Brown S.M.
- Browne T.S.
- Bruhn Alejandro R.
- Brunettini B.
- Bruns M.M.
- Buensuseso J.A.
- Bugedo Guillermo
- Buise M.P.
- Bulpa Pierre A.
- Bumbasierevic Vesna
- Bumbasirevic V.
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- Universitat AutĂČnoma de Barcelona
- Unnikrishnan R.
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- Van Haren Frank
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- Villar Veronica
- Vinzio Mauricio
- Virgilio C.G.
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- Wang C.
- Wang Hua X.
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- Wang Wei
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- Wenham T.
- Wessbergh J.
- Whitehead Christina
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- Williams A.J.
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- Wittebole Xavier
- Wong Helen S.
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- Wrathall D.W.
- Wrigge Hermann
- Wrigge Hermann
- Wu Ya Q.
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- Yamaji Y.
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- Yu R.
- Yu Tao
- Yu Wenkui
- Yumha Jacob S.
- Yuste L.J.
- Zacharas Giannis A
- Zacharowski Kai
- Zani G.
- Zantua C.K.S.
- Zazu Alan
- Zeggwagh Amine Ali
- Zein Salem Ould
- Zender Hervé O
- Zhai Zhe
- Zhang Fan
- Zhang X.Y.
- Zhao Huiying
- Zhao Jun
- Zhao X.Y.
- Zheng Ruiqiang
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- Zhu W.H.
- Zogheib Elie
- Ăamendys-Silva S.A.
- Ănal N.
- Publication venue
- Publication date
- 01/01/2022
- Field of study
Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality. Patients from the LUNG SAFE cohort, a multicenter prospective cohort study of patients undergoing mechanical ventilation, were studied. Relationships between ventilatory parameters and outcomes (ICU discharge/hospital mortality) were assessed using latent mixture analysis and a marginal structural model. From 4499 patients, 391 meeting CPE criteria (median age 70 [interquartile range 59-78], 40% female) were included. ICU and hospital mortality were 34% and 40%, respectively. ICU survivors were younger (67 [57-77] vs 74 [64-80] years, p < 0.001) and had lower driving (12 [8-16] vs 15 [11-17] cmHO, p < 0.001), plateau (20 [15-23] vs 22 [19-26] cmHO, p < 0.001) and peak (21 [17-27] vs 26 [20-32] cmHO, p < 0.001) pressures. Latent mixture analysis of patients receiving invasive mechanical ventilation on ICU day 1 revealed a subgroup ventilated with high pressures with lower probability of being discharged alive from the ICU (hazard ratio [HR] 0.79 [95% confidence interval 0.60-1.05], p = 0.103) and increased hospital mortality (HR 1.65 [1.16-2.36], p = 0.005). In a marginal structural model, driving pressures in the first week (HR 1.12 [1.06-1.18], p < 0.001) and tidal volume after day 7 (HR 0.69 [0.52-0.93], p = 0.015) were related to survival. Higher airway pressures in invasively ventilated patients with CPE are related to mortality. These patients may be exposed to an increased risk of ventilator-induced lung injury. Trial registration Clinicaltrials.gov NCT02010073