1 research outputs found
A Short Covalent Synthesis of an All-Carbon-Ring [2]Rotaxane
While
the current supramolecular syntheses of [2]rotaxanes are
generally efficient, the final product always retains the functional
groups required for non-covalent preorganization. A short and high-yielding
covalent-template-assisted approach is reported for the synthesis
of a [2]rotaxane. A terephthalic acid template core preorganizes the
covalently connected ring precursor fragments to induce a clipping-type
cyclization over the thread moiety. Cleavage of the temporary ester
bonds that connect the ring and thread fragments liberates the [2]rotaxane