2,451 research outputs found
Fast kinetic Monte Carlo simulation of strained heteroepitaxy in three dimensions
Accelerated algorithms for simulating the morphological evolution of strained
heteroeptiaxy based on a ball and spring lattice model in three dimensions are
explained. We derive exact Green's function formalisms for boundary values in
the associated lattice elasticity problems. The computational efficiency is
further enhanced by using a superparticle surface coarsening approximation.
Atomic hoppings simulating surface diffusion are sampled using a multi-step
acceptance-rejection algorithm. It utilizes quick estimates of the atomic
elastic energies from extensively tabulated values modulated by the local
strain. A parameter controls the compromise between accuracy and efficiency of
the acceptance-rejection algorithm.Comment: 10 pages, 4 figures, submitted to Proceedings of Barrett Lectures
2007, Journal of Scientific Computin
Relativistic Quark Spin Coupling Effects in the Nucleon Electromagnetic Form Factors
We investigate the effect of different forms of relativistic spin coupling of
constituent quarks in the nucleon electromagnetic form factors. The
four-dimensional integrations in the two-loop Feynman diagram are reduced to
the null-plane, such that the light-front wave function is introduced in the
computation of the form factors. The neutron charge form factor is very
sensitive to different choices of spin coupling schemes, once its magnetic
moment is fitted to the experimental value. The scalar coupling between two
quarks is preferred by the neutron data, when a reasonable fit of the proton
magnetic momentum is found.Comment: 13 pages, needs axodraw.ps and axodraw.sty for diagrams of Fig.
Scalar Top Quark as the Next-to-Lightest Supersymmetric Particle
We study phenomenologically the scenario in which the scalar top quark is
lighter than any other standard supersymmetric partner and also lighter than
the top quark, so that it decays to the gravitino via stop -> W^+ b G. In this
case, scalar top quark events would seem to be very difficult to separate from
top quark pair production. However, we show that, even at a hadron collider, it
is possible to distinguish these two reactions. We show also that the
longitudinal polarization of the final gives insight into the scalar top
and wino/Higgsino mixing parameters.Comment: 18 pages, LaTeX, 7 figures, minor typographical correction
Macrophage-Tropic HIV Induces and Exploits Dendritic Cell Chemotaxis
Immature dendritic cells (iDCs) express the CC chemokine receptor (CCR)5, which promotes chemotaxis toward the CC chemokines regulated on activation, normal T cell expressed and secreted (RANTES), macrophage inflammatory protein (MIP)-1α, and MIP-1β. By contrast, mature DCs downregulate CCR5 but upregulate CXC chemokine receptor (CXCR)4, and as a result exhibit enhanced chemotaxis toward stromal cell–derived factor (SDF)-1α. CCR5 and CXCR4 also function as coreceptors for macrophage-tropic (M-tropic) and T cell–tropic (T-tropic) human immunodeficiency virus (HIV)-1, respectively. Here, we demonstrate chemotaxis of iDCs toward M-tropic (R5) but not T-tropic (X4) HIV-1. Furthermore, preexposure to M-tropic HIV-1 or its recombinant envelope protein prevents migration toward CCR5 ligands. The migration of iDCs toward M-tropic HIV-1 may enhance formation of DC–T cell syncytia, thus promoting viral production and destruction of both DC and T helper lymphocytes. Therefore, disturbance of DC chemotaxis by HIV-1 is likely to contribute to immunosuppression in primary infection and AIDS. In addition, migration of iDCs toward HIV-1 may aid the capture of R5 HIV-1 virions by the abundant DC cell surface protein DC-specific intercellular adhesion molecule (ICAM)3-grabbing nonintegrin (DC-SIGN). HIV-1 bound to DC cell–specific DC-SIGN retains the ability to infect replication-permissive T cells in trans for several days. Consequently, recruitment of DC by HIV-1 could combine with the ability of DC-SIGN to capture and transmit the virus to T cells, and so facilitate dissemination of virus within an infected individual
Yang's gravitational theory
Yang's pure space equations (C.N. Yang, Phys. Rev. Lett. v.33, p.445 (1974))
generalize Einstein's gravitational equations, while coming from gauge theory.
We study these equations from a number of vantage points: summarizing the work
done previously, comparing them with the Einstein equations and investigating
their properties. In particular, the initial value problem is discussed and a
number of results are presented for these equations with common energy-momentum
tensors.Comment: 28 pages, to appear in Gen. Rel. Gra
On high-speed turning of a third-generation gamma titanium aluminide
Gamma titanium aluminides are heat-resistant intermetallic alloys predestined to be employed in components suffering from high mechanical stresses and thermal loads. These materials are regarded as difficult to cut, so this makes process adaptation essential in order to obtain high-quality and defect-free surfaces suitable for aerospace and automotive parts. In this paper, an innovative approach for longitudinal external high-speed turning of a third-generation Ti-45Al-8Nb- 0.2C-0.2B gamma titanium aluminide is presented. The experimental campaign has been executed with different process parameters, tool geometries and lubrication conditions. The results are discussed in terms of surface roughness/integrity, chip morphology, cutting forces and tool wear. Experimental evidence showed that, due to the high cutting speed, the high temperatures reached in the shear zone improve chip formation, so a crack-free surface can be obtained. Furthermore, the use of a cryogenic lubrication system has been identified in order to reduce the huge tool wear, which represents the main drawback when machining gamma titanium aluminides under the chosen process condition
Octet-Baryon Form Factors in the Diquark Model
We present an alternative parameterization of the quark-diquark model of
baryons which particularly takes care of the most recent proton electric
form-factor data from the E136 experiment at SLAC. In addition to
electromagnetic form factors of the nucleon, for which good agreement with data
is achieved, we discuss the weak axial vector form factor of the nucleon as
well as electromagnetic form factors of and hyperons.
Technical advance in calculating the pertinent analytic expressions within
perturbative quantum chromodynamics is gained by formulating the wave function
of the quark-diquark system in a covariant way. Finally, we also comment on the
influence of Sudakov corrections within the scope of the diquark model.Comment: 16 pages, WU-B 93-07, latex, uuencoded postscript files of 7 figures
appended at the end of the latex fil
The native cistrome and sequence motif families of the maize ear
Elucidating the transcriptional regulatory networks that underlie growth and development requires robust ways to define the complete set of transcription factor (TF) binding sites. Although TF-binding sites are known to be generally located within accessible chromatin regions (ACRs), pinpointing these DNA regulatory elements globally remains challenging. Current approaches primarily identify binding sites for a single TF (e.g. ChIP-seq), or globally detect ACRs but lack the resolution to consistently define TF-binding sites (e.g. DNAse-seq, ATAC-seq). To address this challenge, we developed MNase-defined cistrome-Occupancy Analysis (MOA-seq), a high-resolution (< 30 bp), high-throughput, and genome-wide strategy to globally identify putative TF-binding sites within ACRs. We used MOA-seq on developing maize ears as a proof of concept, able to define a cistrome of 145,000 MOA footprints (MFs). While a substantial majority (76%) of the known ATAC-seq ACRs intersected with the MFs, only a minority of MFs overlapped with the ATAC peaks, indicating that the majority of MFs were novel and not detected by ATAC-seq. MFs were associated with promoters and significantly enriched for TF-binding and long-range chromatin interaction sites, including for the well-characterized FASCIATED EAR4, KNOTTED1, and TEOSINTE BRANCHED1. Importantly, the MOA-seq strategy improved the spatial resolution of TF-binding prediction and allowed us to identify 215 motif families collectively distributed over more than 100,000 non-overlapping, putatively-occupied binding sites across the genome. Our study presents a simple, efficient, and high-resolution approach to identify putative TF footprints and binding motifs genome-wide, to ultimately define a native cistrome atlas
Hadron Polarizabilities and Form Factors
This is the summary of the working group on Hadron Polarizabilities and Form
Factors of the Chiral Dynamics Workshop in Mainz, September 1-5, 1997.Comment: 21 pages LaTeX2e, uses epsf, 9 fig
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