A theoretical investigation of the aerodynamics of slender wing-body combinations exhibiting leading-edge separation

Theoretical investigation of aerodynamics of slender wing-body combinations exhibiting leading edge separatio

SBASI: Actuated pyrotechnic time delay initiator

A precision pyrotechnic time delay initiator for missile staging was developed and tested. Incorporated in the assembly is a single bridgewire Apollo standard initiator (SBASI) for initiation, a through-bulkhead-initiator to provide isolation of the SBASI output from the delay, the pyrotechnic delay, and an output charge. An attempt was made to control both primary and secondary variables affecting functional performance of the delay initiator. Design and functional limit exploration was performed to establish tolerance levels on manufacturing and assembling operations. The test results demonstrate a 2% coefficient of variation at any one temperature and an overall 2.7% coefficient of variation throughout the temperature range of 30 to 120 F. Tests were conducted at simulated operational altitude from sea level to 200,000 feet

HEAT TRANSFER WITH LAMINAR FLOW IN CONCENTRIC ANNULI WITH CONSTANT AND VARIABLE WALL TEMPERATURE AND HEAT FLUX

Heat transfer with laminar flow in concentric annuli with constant and variable wall temperature and heat flu

Phenex: Ontological Annotation of Phenotypic Diversity

Phenex is a platform-independent desktop application designed to facilitate efficient and consistent annotation of phenotypic variation using Entity-Quality syntax, drawing on terms from community ontologies for anatomical entities, phenotypic qualities, and taxonomic names. Despite the centrality of the phenotype to so much of biology, traditions for communicating information about phenotypes are idiosyncratic to different disciplines. Phenotypes seem to elude standardized descriptions due to the variety of traits that compose them and the difficulty of capturing the complex forms and subtle differences among organisms that we can readily observe. Consequently, phenotypes are refractory to attempts at data integration that would allow computational analyses across studies and study systems. Phenex addresses this problem by allowing scientists to employ standard ontologies and syntax to link computable phenotype annotations to evolutionary character matrices, as well as to link taxa and specimens to ontological identifiers. Ontologies have become a foundational technology for establishing shared semantics, and, more generally, for capturing and computing with biological knowledge

Multi-payload measurement of transverse velocity shears in the topside ionosphere

Using a multi-payload sounding rocket mission, we present the first direct measurement of velocity shear in the topside auroral ionosphere. In regions of large, ∼200 mV/m, transient electric fields we directly measure differences in the plasma drift velocity. From these differences, shear frequencies reaching ±6Hz are measured. These directly measured shears are compared with the shear inferred from single payload measurements. It is shown this traditional measurement of shear overestimates the shear frequency by a factor of two for this event, highlighting the importance of the temporal component of near-DC electric field structures. Coincident with these strong fields and shears are enhanced emissions of broadband, extremely low frequency (BB-ELF) plasma waves, and a narrowband wave emission near the H+-O+bi-ion resonant frequency

Fractional Loop Group and Twisted K-Theory

We study the structure of abelian extensions of the group $L_qG$ of $q$-differentiable loops (in the Sobolev sense), generalizing from the case of central extension of the smooth loop group. This is motivated by the aim of understanding the problems with current algebras in higher dimensions. Highest weight modules are constructed for the Lie algebra. The construction is extended to the current algebra of supersymmetric Wess-Zumino-Witten model. An application to the twisted K-theory on $G$ is discussed.Comment: Final version in Commun. Math. Phy

Putting evolutionary biology back in the ecological theatre: a demographic framework mapping genes to communities

Question: How can we link genotypic, phenotypic, individual, population, and community levels of organization so as to illuminate general ecological and evolutionary processes and provide a framework for a quantitative, integrative evolutionary biology? Framework: We introduce an evolutionary framework that maps different levels of biological diversity onto one another. We provide (1) an overview of maps linking levels of biological organization and (2) a guideline of how to analyse the complexity of relationships from genes to population growth. Method: We specify the appropriate levels of biological organization for responses to selection, for opportunities for selection, and for selection itself. We map between them and embed these maps into an ecological setting

Long Term Follow-Up of the Endovascular Trans-Vessel Wall Technique for Parenchymal Access in Rabbit with Full Clinical Integration

OBJECTIVE: Endovascular techniques are providing options to surgical/percutaneous cell transplantation methods. Some cells, e.g. insulin producing cells, are not suitable for intra-luminal transplantation and for such cells, other options must be found. We have constructed a "nanocatheter" with a penetrating tip for vessel perforation, thereby creating a working channel for parenchymal access by endovascular technique. To finish the procedure safely, the distal tip is detached to provide a securing plug in the vessel wall defect. MATERIALS AND METHODS: We have performed interventions with full clinical integration in the superior mesenteric artery (SMA), the subclavian artery and the external carotid artery in rabbits. No hemorrhagic- or thromboembolic events occurred during the procedure. Stenosis formation and distal embolisation were analyzed by angiography and macroscopic inspection during autopsy at five, 30 and 80 days. All animals and implanted devices were also evaluated by micro-dissections and histochemical analysis. RESULTS: In this study we show safety data on the trans-vessel wall technique by behavioral, angiographical and histological analysis. No stenosis formation was observed at any of the follow-up time points. No animals or organs have shown any signs of distress due to the intervention. Histological examination showed no signs of hemorrhage, excellent biocompatibility with no inflammation and a very limited fibrous capsule formation around the device, comparable to titanium implants. Further, no histological changes were detected in the endothelia of the vessels subject to intervention. CONCLUSIONS: The trans-vessel wall technique can be applied for e.g. cell transplantations, local substance administration and tissue sampling with low risk for complications during the procedure and low risk for hemorrhage, stenosis development or adverse tissue reactions with an 80 days follow-up time. The benefit should be greatest in organs that are difficult or risky to reach with surgical techniques, such as the pancreas, the CNS and the heart

Experiment Simulation Configurations Used in DUNE CDR

The LBNF/DUNE CDR describes the proposed physics program and experimental design at the conceptual design phase. Volume 2, entitled The Physics Program for DUNE at LBNF, outlines the scientific objectives and describes the physics studies that the DUNE collaboration will perform to address these objectives. The long-baseline physics sensitivity calculations presented in the DUNE CDR rely upon simulation of the neutrino beam line, simulation of neutrino interactions in the far detector, and a parameterized analysis of detector performance and systematic uncertainty. The purpose of this posting is to provide the results of these simulations to the community to facilitate phenomenological studies of long-baseline oscillation at LBNF/DUNE. Additionally, this posting includes GDML of the DUNE single-phase far detector for use in simulations. DUNE welcomes those interested in performing this work as members of the collaboration, but also recognizes the benefit of making these configurations readily available to the wider community.Comment: 9 pages, 4 figures, configurations in ancillary file