Best model in multiple regression analysis to predict GAL-9 scores.

<p>Adding any sector of the RNFL or age did not enhance the predictive power.</p

Correlation analysis between important functional parameters and IOP, CCT and RNFL sectors (T: temporal, TS: temporal superior, NS: nasal superior, N: nasal, NI: nasal inferior, TI: temporal inferior, G: global) for better eye (b/e) and worse eye (w/e), respectively.

<p>Cursive numbers are Pearson´s correlation coefficients, otherwise Spearman rank coefficients are displayed. Significant coefficients (p<0.05) are bold.</p

Demographic, biometric and clinical characteristics including the spectral-domain optical coherence tomography (SD-OCT) assessed retinal nerve fibre layer (RNFL) thickness (mean values +/- 1 SD).

<p>Demographic, biometric and clinical characteristics including the spectral-domain optical coherence tomography (SD-OCT) assessed retinal nerve fibre layer (RNFL) thickness (mean values +/- 1 SD).</p

Univariate linear regression.

<p>Dependent variable GAL-9. Visual acuity (VA) and mean defect (MD) were significant predictors for GAL-9 scores with the MD of the better eye revealing best modelling (R²=0.279). The only significant predictor of structural parameters was the retinal nerve fibre layer (RNFL) of the temporal superior (TS) sector of the worse eye. IOP: intraocular pressure, CCT: central corneal thickness, PSD: pattern standard deviation, CDR: cup-to-disc ratio.</p

Media 1: Multi-MHz retinal OCT

Originally published in Biomedical Optics Express on 01 October 2013 (boe-4-10-1890

Media 2: Multi-MHz retinal OCT

Originally published in Biomedical Optics Express on 01 October 2013 (boe-4-10-1890

Media 3: Multi-MHz retinal OCT

Originally published in Biomedical Optics Express on 01 October 2013 (boe-4-10-1890

Best-Corrected Visual Acuity (BCVA) and Central Retinal Thickness (CRT) changes at month 12.

<p>SD, standard deviation; CI, confidence interval; CRT, central retinal thickness; BCVA, best corrected visual acuity; ETDRS, Early Treatment Diabetic Retinopathy Study.</p><p>Best-Corrected Visual Acuity (BCVA) and Central Retinal Thickness (CRT) changes at month 12.</p

Analysis of required treatments.

<p>SD, standard deviation.</p><p>Analysis of required treatments.</p

Flow chart of the study.

<p>Enrollment, Assignment and Follow-up of the patients that were included in this prospective comparison of combined navigated macula laser therapy and mono anti-VEGF therapy.</p