Validation test for Hsp72 in a similar population in ICU.

<p>Use of cut-off value one day before AKI diagnosis (AKIN criteria). PPV = Positive Predictive Value. NPV = Negative Predictive Value.</p><p>Validation test for Hsp72 in a similar population in ICU.</p

Summary of baseline and clinical characteristics.

<p>Continuous values are represented as mean ± standard deviation; dichotomous values are <i>N</i> (%). AKI: Acute Kidney Injury. ICU: Intensive Care Unit. SLE: Systemic Lupus Erythematosus. APS: Antiphospholipid Syndrome.</p><p>Summary of baseline and clinical characteristics.</p

Kim-1 in critically ill patients after ICU admission.

<p>A) Urinary Kim-1 levels assessed by ELISA from AKI and no-AKI patients. In no-AKI patients, Kim-1 was measured at days 1, 5 and 10 of their stay in the ICU; whereas, in AKI patients Kim-1 was measured from ICU admission until two days after the diagnosis of AKI. Every point represents the biomarker value in each urine sample, and the lines depicted the mean and 95% confident interval. AVG = average of urinary Kim-1 levels in no-AKI patients determinated at 1, 5, and 10 days after ICU admission. B) Specificity and sensitivity of Kim-1 to detect AKI two days before the AKIN criteria, determined by ROC analysis. C) Specificity and sensitivity of Kim-1 to detect AKI one day before the AKIN criteria, determined by ROC analysis.</p

IL-18 in critically ill patients after ICU admission.

<p>A) Urinary IL-18 levels assessed by ELISA from AKI and no-AKI patients. Every point represents the biomarker value in each urine sample, and the lines depicted the mean and 95% confident interval. AVG = average of urinary IL-18 levels in no-AKI patients determinated at 1, 5, and 10 days after ICU admission. B) Specificity and sensitivity of IL-18 to detect AKI two days before the AKIN criteria, determined by ROC analysis. C) Specificity and sensitivity of IL-18 to detect AKI one day before the AKIN criteria, determined by ROC analysis.</p

Hsp72 in critically ill patients after their admission at ICU.

<p>A) Urinary Hsp72 levels assessed by ELISA from AKI and no-AKI patients. Every point represents the biomarker value in each urine sample, and the lines depicted the mean and 95% confident interval. AVG = average of urinary Hsp72 levels in no-AKI patients determinated at 1, 5, and 10 days after ICU admission. B) Specificity and sensitivity of Hsp72 to detect AKI two days before the AKIN criteria, determined by ROC analysis. C) Specificity and sensitivity of Hsp72 to detect AKI one day before the AKIN criteria, determined by ROC analysis.</p