9 research outputs found
Exploring the sources of meaning in life among Chinese advanced cancer patients
Free Paper Session - Psychosocial Oncology: abstract no. A57The 17th Hong Kong International Cancer Congress (HKICC 2010), Hong Kong, 3-5 November 2010
Let the dying shine: are they lessons of dying or lessons of living? Meaning making of patients with terminal cancer in Chinese cultural context
Free Paper Session - Psychosocial Oncology: A65The 16th Hong Kong International Cancer Congress (HKICC 2009), Hong Kong, 4-6 November 2009
A randomized control trial on impact of a Satir-based intervention on psychosocial outcomes of Chinese people with chronic illness
The 2010 Joint World Conference on Social Work and Social Development, Hong Kong, 10-14 June 2010
Identification and Characterization of Human VCY2-Interacting Protein: VCY2IP-1, a Microtubule-Associated Protein-Like Protein
VCY2 is a testis-specific protein that locates in a frequently deleted azoospermia factor c region on chromosome Yq. Although its genomic structure has been characterized, the function of VCY2 is still unknown. To gain insight regarding the likely function of VCY2, we investigated the proteins that interact with VCY2 using the yeast two-hybrid system. We identified a novel VCY2 interaction partner, named VCY2IP-1, that encodes an open reading frame of 1059 amino acids. The amino acid sequence of VCY2IP-1 shows 59.3% and 41.9% homology to two human microtubule-associated proteins (MAPs), MAP1B and MAP1A, respectively. VCY2IP-1 has an extensive homology to the N-terminus and C-terminus regions of MAP1B and MAP1A, placing it within a large family of MAPs. We mapped VCY2IP-1 to chromosome 19p13.11. The VCY2IP-1 gene spans 15 kilobases (kb) and consists of seven exons. Northern blot analysis identified a single, intense band of approximately 3.2-kb VCY2IP-1 transcript, predominantly expressed in human testis. In situ hybridization of human testicular sections showed the localization of VCY2IP-1 transcripts in germ cells, and reverse transcription-polymerase chain reaction analysis demonstrated the presence of VCY2 and VCY2IP-1 transcripts in human ejaculated spermatozoa. Our expression data support the involvement of VCY2 and VCY2IP-1 in spermatogenesis. Based on the high homology of VCY2IP-1 with MAPs, we propose the involvement of VCY2 in the cytoskeletal network via interaction with VCY2IP-1.link_to_subscribed_fulltex
Peace within, peace between: enhancing interpersonal relationship using a Satir-based group intervention in a community rehabilitation setting
Theme: Synergy for a Peaceful World - Healthy Individual, Happy Family, Harmonious WorkplaceThe 2010 Satir World Conference, Hong Kong Baptist University, Hong Kong, 15-19 June 2010
Identification and Characterization of Human VCY2-Interacting Protein: VCY2IP-1, a Microtubule-Associated Protein-Like Protein
VCY2 is a testis-specific protein that locates in a frequently deleted azoospermia factor c region on chromosome Yq. Although its genomic structure has been characterized, the function of VCY2 is still unknown. To gain insight regarding the likely function of VCY2, we investigated the proteins that interact with VCY2 using the yeast two-hybrid system. We identified a novel VCY2 interaction partner, named VCY2IP-1, that encodes an open reading frame of 1059 amino acids. The amino acid sequence of VCY2IP-1 shows 59.3% and 41.9% homology to two human microtubule-associated proteins (MAPs), MAP1B and MAP1A, respectively. VCY2IP-1 has an extensive homology to the N-terminus and C-terminus regions of MAP1B and MAP1A, placing it within a large family of MAPs. We mapped VCY2IP-1 to chromosome 19p13.11. The VCY2IP-1 gene spans 15 kilobases (kb) and consists of seven exons. Northern blot analysis identified a single, intense band of approximately 3.2-kb VCY2IP-1 transcript, predominantly expressed in human testis. In situ hybridization of human testicular sections showed the localization of VCY2IP-1 transcripts in germ cells, and reverse transcription-polymerase chain reaction analysis demonstrated the presence of VCY2 and VCY2IP-1 transcripts in human ejaculated spermatozoa. Our expression data support the involvement of VCY2 and VCY2IP-1 in spermatogenesis. Based on the high homology of VCY2IP-1 with MAPs, we propose the involvement of VCY2 in the cytoskeletal network via interaction with VCY2IP-1.link_to_subscribed_fulltex
The effect of a Satir-based psychosocial group in enhancing self esteem and interpersonal relationship of persons with chronic illness in Hong Kong: a randomized control trial
Conference Theme: Towards a Community-based Chronic Care Model for AsiaThe 2010 International Conference on Promoting Chronic Care, Hong Kong Polytechnic University, Hong Kong, 8-10 January 2010
Love life as it is: an evaluation on a life and death educational group for people with chronic diseases in Hong Kong
Conference Theme: Towards a Community -based Chronic Care Model for AsiaThe 2010 International Conference on Promoting Chronic Care, Hong Kong Polytechnic University, Hong Kong, 8-10 January 2010
The Effects of a Positive Death Education Group on Psycho-Spiritual Outcomes for Chinese with Chronic Illness: A Quasi-Experimental Study
Traditionally, death is a taboo subject in Chinese culture. However, very few studies examine the effects of death education program on the psycho-spiritual outcomes among Chinese patients. This article reports on a quasi-experimental study on Chinese patients with chronic diseases who participated in a psycho-education group on positive death preparation. Findings revealed that participants in the intervention group (n = 81) reported significantly greater reduction in fear of death, death avoidance, greater increase in death acceptance, death preparation, tranquility and spiritual well-being at immediate post-intervention than the control group (n = 79). It is also found that levels of death-related fear and avoidance in the intervention group were significantly lower at 1–month follow-up when compared with baseline. This study challenges the assumption that Chinese people are not receptive to intervention that addresses issues of death and dying. Implications of conducting death education program among a culturally diverse population are discussed