1 research outputs found
New Organochalcogen Multitarget Drug: Synthesis and Antioxidant and Antitumoral Activities of Chalcogenozidovudine Derivatives
In
this article we present the synthesis, characterization, and
in vitro biological and biochemical activities of new chalcogenozidovudine
derivatives as antioxidant (inhibition of TBARS in brain membranes
and thiol peroxidase-like activity) as well as antitumoral agents
in bladder carcinoma 5637. A prominent response was obtained for the
selected chalcogenonucleosides, showing effective antioxidant and
antitumoral activities