Bacterial phyla whose globins may share ancestry with fungal globins.

<p>Bacterial phyla whose globins may share ancestry with fungal globins.</p

Bayesian phylogenetic tree of fungal FHbs.

<p>Bayesian tree based on a MAFFT v.6.850 alignment of 62 fungal FHb globin domains using two plant nonsymbiotic Hbs as outgroup. Support values at branches represent Bayesian posterior probabilities (>0.5). The sequences are identified by the first three letters of the binary species name, the number of residues, and the full phylum and family names (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856.s011" target="_blank">Table S1</a>). Sac – Saccharomycetes.</p

Bayesian phylogenetic tree of fungal and bacterial T1 globins.

<p>Bayesian tree based on a T-COFFEE 9.01 alignment of 2 fungal (red and black arrows), 70 bacterial (blue), 4 euryarchaeote (purple) and 10 chlorophyte (green) T1 globins, using 2 <i>Physcomitrella</i> nsHbs as outgroup. Support values at branches represent Bayesian posterior probabilities (>0.5). All the bacterial FHbs are in the blue boxes. The sequences are identified by the first three letters of the binary species name, the number of residues, and the full phylum and family names (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856.s011" target="_blank">Table S1</a>).</p

Bayesian phylogenetic tree of fungal and bacterial Sgbs.

<p>Bayesian tree based on a T-COFFEE 9.01 alignment of 51 fungal, 57 bacterial (including 16 Pgbs), one rotifer and one heterolobosan Sgbs, using two Adgb sequences <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856-Hoogewijs1" target="_blank">[16]</a> as outgroup. Support values at branches represent Bayesian posterior probabilities (>0.5). The sequences are identified by the first three letters of the binary species name, the number of residues, and the full phylum and family names (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856.s011" target="_blank">Table S1</a>).</p

Bayesian phylogenetic tree of fungal and bacterial FHbs.

<p>Bayesian tree based on a T-COFFEE 9.01 alignment of the globin domains of 55 representative fungal FHbs and 54 representative bacterial FHbs. Support values at branches represent Bayesian posterior probabilities (>0.5). All the bacterial FHbs are in the blue boxes. The sequences are identified by the first three letters of the binary species name, the number of residues, and the full phylum and family names (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856.s011" target="_blank">Table S1</a>). Sac – Saccharomycetes.</p

Diagrammatic representation of fungal phylogeny based on ref. 18 and of their putative globins.

<p>Estimates of the numbers of species in parentheses are from the <i>Dictionary of the Fungi </i><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0031856#pone.0031856-Kirk1" target="_blank">[23]</a>. Red bar indicates multicellularity with differentiated tissues; FHb* - unknown N-terminal domain linked to a FHb with an incomplete reductase domain, T1gb - T globin group1. Ratios refer to the number of genomes containing globins versus the total number of genomes analyzed.</p

Expression levels of globin genes in young adults relative to young adult worms

<p><b>Copyright information:</b></p><p>Taken from "Wide diversity in structure and expression profiles among members of the globin protein family"</p><p>http://www.biomedcentral.com/1471-2164/8/356</p><p>BMC Genomics 2007;8():356-356.</p><p>Published online 4 Oct 2007</p><p>PMCID:PMC2228317.</p><p></p> The expression ratio's are the average values from 3 replicate cultures (biological repeats). Bars indicate the 95% confidence interval of the mean

Levels of globin expression in third stage larvae (L3) and the alternative dauer (diapause) stage, relative to expression in young adult animals

<p><b>Copyright information:</b></p><p>Taken from "Wide diversity in structure and expression profiles among members of the globin protein family"</p><p>http://www.biomedcentral.com/1471-2164/8/356</p><p>BMC Genomics 2007;8():356-356.</p><p>Published online 4 Oct 2007</p><p>PMCID:PMC2228317.</p><p></p> The expression ratio's are the average values from 3 replicate cultures (biological repeats). Bars indicate the 95% confidence interval of the mean. Only globins that showed a significant (borderline for C36E8.2) difference in one of the three comparisons are displayed

Expression levels of globin genes in young adults under normoxia or following 12 h exposure to anoxic conditions, relative to wild-type young adult worms under normoxia

<p><b>Copyright information:</b></p><p>Taken from "Wide diversity in structure and expression profiles among members of the globin protein family"</p><p>http://www.biomedcentral.com/1471-2164/8/356</p><p>BMC Genomics 2007;8():356-356.</p><p>Published online 4 Oct 2007</p><p>PMCID:PMC2228317.</p><p></p> The expression ratio's are the average values from 3 replicate cultures (biological repeats). Bars indicate the 95% confidence interval of the mean. Only globins that showed a significant (borderline for T22C1.2) difference normoxia N2 vs. normoxia are displayed

Expression level of under anoxic conditions in young adults relative to N2 young adult worms

<p><b>Copyright information:</b></p><p>Taken from "Wide diversity in structure and expression profiles among members of the globin protein family"</p><p>http://www.biomedcentral.com/1471-2164/8/356</p><p>BMC Genomics 2007;8():356-356.</p><p>Published online 4 Oct 2007</p><p>PMCID:PMC2228317.</p><p></p> The expression ratio's are the average values from 4 replicate cultures (biological repeats). Bars indicate the 95% confidence interval of the mean