BOTT: Box Only Transformer Tracker for 3D Object Tracking

Tracking 3D objects is an important task in autonomous driving. Classical Kalman Filtering based methods are still the most popular solutions. However, these methods require handcrafted designs in motion modeling and can not benefit from the growing data amounts. In this paper, Box Only Transformer Tracker (BOTT) is proposed to learn to link 3D boxes of the same object from the different frames, by taking all the 3D boxes in a time window as input. Specifically, transformer self-attention is applied to exchange information between all the boxes to learn global-informative box embeddings. The similarity between these learned embeddings can be used to link the boxes of the same object. BOTT can be used for both online and offline tracking modes seamlessly. Its simplicity enables us to significantly reduce engineering efforts required by traditional Kalman Filtering based methods. Experiments show BOTT achieves competitive performance on two largest 3D MOT benchmarks: 69.9 and 66.7 AMOTA on nuScenes validation and test splits, respectively, 56.45 and 59.57 MOTA L2 on Waymo Open Dataset validation and test splits, respectively. This work suggests that tracking 3D objects by learning features directly from 3D boxes using transformers is a simple yet effective way

Chan-Chuang and resistance exercise for drug rehabilitation: a randomized controlled trial among Chinese male methamphetamine users

ObjectiveTo examine the health benefits of Chan-Chuang and resistance exercise.MethodsWe deployed an 8-week randomized controlled trial, in which 76 male methamphetamine users were allocated to control (n = 25), Chan-Chuang (n = 26), and residence exercise groups (n = 25). Our primary outcomes were drug craving, mental wellbeing, sleep quality, heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial pressure (MAP). Our secondary outcomes were body mass index (BMI), vital capacity, grip strength, balance, and vertical jump.ResultsChan-Chuang exercise resulted in reduced HR, DBP, and MAP, along with improvements in vital capacity, grip strength, and balance compared to the control group. Resistance exercise reduced SBP and MAP, and also improved vital capacity, grip strength, balance, and vertical jump.ConclusionThese findings may support the role of Chan-Chuang and resistance exercise in maintaining the physical fitness of methamphetamine users at mandatory detention centers

Immunostimulatory Activity of Protein Hydrolysate from Oviductus Ranae on Macrophage In Vitro

Oviductus Ranae is the dry oviduct of Rana chensinensis, which is also called R. chensinensis oil. Oviductus Ranae is a valuable Chinese crude drug and is recorded in the Pharmacopoeia of the People’s Republic of China. The aim of this study was to investigate the immunostimulatory activity of protein hydrolysate of Oviductus Ranae (ORPH) and to assess its possible mechanism. Immunomodulatory activity of ORPH was examined in murine macrophage RAW 264.7 cells. The effect of ORPH on the phagocytic activity of macrophages was determined by the neutral red uptake assay. After treatment with ORPH, NO production levels in the culture supernatant were investigated by Griess assay. The mRNA and protein expressions of inducible nitric oxide synthase (iNOS) were detected by RT-PCR and Western blotting. The production of TNF-α, IL-1β, and IL-6 after treatment with ORPH was measured using ELISA assay. In addition, NF-κB levels were also investigated by Western blot. The results showed that ORPH enhanced the phagocytosis of macrophage, increased productions of TNF-α, IL-1β, IL-6, and NO in RAW 264.7 cells, and upregulated the mRNA and protein expression of iNOS. Besides, NF-κB, levels in RAW 264.7 cells were elevated after ORPH treatment. These findings suggested that ORPH might stimulate macrophage activities by activating the NF-κB pathway

Walnut Polyphenol Extract Attenuates Immunotoxicity Induced by 4-Pentylphenol and 3-methyl-4-nitrophenol in Murine Splenic Lymphocyte

4-pentylphenol (PP) and 3-methyl-4-nitrophenol (PNMC), two important components of vehicle emissions, have been shown to confer toxicity in splenocytes. Certain natural products, such as those derived from walnuts, exhibit a range of antioxidative, antitumor, and anti-inflammatory properties. Here, we investigated the effects of walnut polyphenol extract (WPE) on immunotoxicity induced by PP and PNMC in murine splenic lymphocytes. Treatment with WPE was shown to significantly enhance proliferation of splenocytes exposed to PP or PNMC, characterized by increases in the percentages of splenic T lymphocytes (CD3+ T cells) and T cell subsets (CD4+ and CD8+ T cells), as well as the production of T cell-related cytokines and granzymes (interleukin-2, interleukin-4, and granzyme-B) in cells exposed to PP or PNMC. These effects were associated with a decrease in oxidative stress, as evidenced by changes in OH, SOD, GSH-Px, and MDA levels. The total phenolic content of WPE was 34,800 ± 200 mg gallic acid equivalents/100 g, consisting of at least 16 unique phenols, including ellagitannins, quercetin, valoneic acid dilactone, and gallic acid. Taken together, these results suggest that walnut polyphenols significantly attenuated PP and PNMC-mediated immunotoxicity and improved immune function by inhibiting oxidative stress

Thermal Strain Detection for Concrete Structure Cold Shrinkage under Stress Constraint with FBG

Additional strain increments occur in concrete subject to stress constraints during cold shrinkage, resulting in irregular deformation and reducing the concrete structure’s stability. When an annular concrete structure is subjected to radial pressure, two tensile stress concentration zones will appear at the intersection of the inner wall and the diameter along the pressure direction. When exposed to low temperatures, the total strain in the tensile stress concentration zones is caused by the combined effect of applied stress strain and thermal strain. Then, the thermal strain of the structure can be obtained from the difference between the total strain and the applied stress strain. Gradient cooling was performed after applying radial pressure to the annular concrete using a counterforce device. The applied stress strain and total strain of the tensile stress concentration zones are measured by fiber Bragg grating (FBG) strain sensors fixed along the stress direction. According to the measurement results, the thermal strains of the concrete structure under the stress constraint are extracted to analyze the influence of the tensile stress constraint on the thermal strain of the concrete structure. In the temperature range of −40∘C∼20∘C, the thermal strains of the structure under radial pressures of 1500 N, 2000 N, and 3000 N are extracted, respectively. The thermal expansion coefficients are calculated based on the thermal strain of the structure. The free thermal expansion coefficient of concrete structures fluctuates around 11×10−6/∘C. When the temperature is reduced to 10∘C, the difference between the thermal expansion coefficient under the stress constraint and the free thermal expansion coefficient is the largest. When the temperature is reduced to −20∘C, the thermal expansion coefficients under each stress condition are close to the same. The results show that the stress confinement significantly inhibits the cold shrinkage of the concrete structure, and the inhibitory effect is gradually weakened when the temperature decreases

Based on event-triggered anti-disturbance tracking control for hypersonic flight vehicles with T-S disturbance modeling

In this paper, a novel based on event-triggered anti-disturbance dynamical tracking control is discussed for HFVs with unknown exogenous disturbances. Firstly, the event-triggered mechanism is introduced into the control system. Secondly, the external disturbance is described by T-S model and estimated by disturbance observer. Next, by combining state feedback with disturbance estimation, a PI-type feedback controller is proposed to ensure the HFV models stability and the output tracking error convergence zero. Finally, the simulation result shows the algorithm is effective. Meanwhile, it can obtain satisfactory tracking performance and anti-disturbance tracking performance