602 research outputs found
DNA Immunization for HIV Vaccine Development
DNA vaccination has been studied in the last 20 years for HIV vaccine research. Significant experience has been accumulated in vector design, antigen optimization, delivery approaches and the use of DNA immunization as part of a prime-boost HIV vaccination strategy. Key historical data and future outlook are presented. With better understanding on the potential of DNA immunization and recent progress in HIV vaccine research, it is anticipated that DNA immunization will play a more significant role in the future of HIV vaccine development
Latent Semantic Learning with Structured Sparse Representation for Human Action Recognition
This paper proposes a novel latent semantic learning method for extracting
high-level features (i.e. latent semantics) from a large vocabulary of abundant
mid-level features (i.e. visual keywords) with structured sparse
representation, which can help to bridge the semantic gap in the challenging
task of human action recognition. To discover the manifold structure of
midlevel features, we develop a spectral embedding approach to latent semantic
learning based on L1-graph, without the need to tune any parameter for graph
construction as a key step of manifold learning. More importantly, we construct
the L1-graph with structured sparse representation, which can be obtained by
structured sparse coding with its structured sparsity ensured by novel L1-norm
hypergraph regularization over mid-level features. In the new embedding space,
we learn latent semantics automatically from abundant mid-level features
through spectral clustering. The learnt latent semantics can be readily used
for human action recognition with SVM by defining a histogram intersection
kernel. Different from the traditional latent semantic analysis based on topic
models, our latent semantic learning method can explore the manifold structure
of mid-level features in both L1-graph construction and spectral embedding,
which results in compact but discriminative high-level features. The
experimental results on the commonly used KTH action dataset and unconstrained
YouTube action dataset show the superior performance of our method.Comment: The short version of this paper appears in ICCV 201
Content Creator versus Brand Advertiser? The Effect of Inserting Advertisements in Videos on Influencers Engagement
Influencer advertising has become an indispensable component of online marketing due to the exponential growth of social influencers and their influence. Whereas the effectiveness of using influencer endorsements is well studied from the brand or company perspective, how the commercial endorsements affect influencers themselves is an important yet unrevealed question. We empirically examine the instantaneous (measured using live comment sentiment) and longer-term (measured using video feedback and follower number change) influence of inserting advertisements in videos on influencersâ reputation. We further investigate how this effect can be moderated when influencers demonstrate stronger endorsement by showing their faces during advertisements. Our result suggests that inserting advertisements have a negative impact on both instantaneous and longer-term viewer engagement; advertisements with influencersâ face showing moderate the negative effect of advertisements on viewersâ instantaneous response, while the different impact between advertisements with/out influencers showing their faces is not significant in the longer term
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