Priorities for synthesis research in ecology and environmental science

ACKNOWLEDGMENTS We thank the National Science Foundation grant #1940692 for financial support for this workshop, and the National Center for Ecological Analysis and Synthesis (NCEAS) and its staff for logistical support.Peer reviewedPublisher PD

Priorities for synthesis research in ecology and environmental science

ACKNOWLEDGMENTS We thank the National Science Foundation grant #1940692 for financial support for this workshop, and the National Center for Ecological Analysis and Synthesis (NCEAS) and its staff for logistical support.Peer reviewedPublisher PD

Urban regeneration in Glasgow: Looking to the past to build the future? The case of the ‘New Gorbals’

The Gorbals area of Glasgow, Scotland, is widely regarded as a successful example of urban regeneration. However, this neighbourhood, like many similar working-class urban areas, has been subjected to repeated cycles of renewal. This chapter seeks to explore the history of a ‘successful’ regeneration, looking both spatially and socially at what has happened in Glasgow’s Gorbals over the long term. In the past, ‘regeneration’ was often a process enacted on behalf of residents by planners, architects and municipal authorities. We posit a multi-method approach, tracking changing policy ambitions, physical change, and exploring the resulting physical and social environments in order to investigate the complex inter-relations between space, place, community and time. The authors argue for the centrality of the narratives of those who have lived in the area both in the past and today in any assessment of relative ‘success’

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10 -10), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10 -10) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10 -10) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC.</p