4 research outputs found
Synergistic Induction of Apoptosis by p53-inducible Bcl-2 Family Proteins Noxa and Puma
- Author
- Antignani A Youle RJ
- Certo M Del Gaizo V Moore, Nishino M, et al.
- Cochran AG
- GROSS A
- Konopleva M Contractor R, Tsao T, et al.
- Letai A Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ
- Lowe SW Cepero E, Evan G
- Nobuyuki Tanaka
- Soussi T Beroud C
- van Delft MF Wei AH, Mason KD, et al.
- WANG X
- Wataru Nakajima
- You H Pellegrini M, Tsuchihara K, et al.
- Publication venue
- 'Medical Association of Nippon Medical School'
- Publication date
- 01/01/2007
- Field of study
Intrinsic tumour suppression
- Author
- A Aslanian
- A Damalas
- A Egle
- A Kauffmann-Zeh
- A Yang
- AM Pierce
- AW Lin
- B Elenbaas
- B Vogelstein
- C Gaiddon
- C Guerra
- C Scaffidi
- C Yin
- CA Schmitt
- CA Schmitt
- CA Schmitt
- CJ Sherr
- CM Eischen
- CM Eischen
- CW Conn
- D Askew
- D Bergamaschi
- D LeRoith
- D Perez
- D Tolbert
- DA Tuveson
- DR Green
- DR Plas
- DW Felsher
- E de Stanchina
- E White
- EA Conner
- EA Harrington
- EJ Gunther
- Enrique Cepero
- ER Flores
- EW Verschuren
- F Zindy
- F Zindy
- G Christofori
- G Ferbeyre
- G Leone
- G Leone
- Gerard Evan
- GI Evan
- GI Evan
- GP Dimri
- H Harlin
- H Symonds
- HA Rogoff
- HG Wendel
- I Matsumura
- I Vivanco
- J Campisi
- J Grossmann
- J Klefstrom
- J Sage
- J Seoane
- JA Benanti
- JC Wilkinson
- JJ Jacobs
- JL Russell
- JM Grad
- JM Paramio
- JS Fridman
- JW Shay
- K Itahana
- KS Kelly-Spratt
- L Chin
- M Mihara
- M Narita
- M Pearson
- M Senoo
- M Serrano
- M Urist
- MC Raff
- ME Peter
- MJ Liao
- MS Irwin
- MT Hemann
- NN Danial
- R Croxton
- R Sears
- RI Pakunlu
- RW Johnstone
- S Cory
- S Jin
- S Orsulic
- S Pelengaris
- S Pelengaris
- Scott W. Lowe
- SE Moody
- SH Khan
- SM Horner
- SW Lowe
- T Hershko
- T Kamijo
- TA Baudino
- TS Zheng
- VJ Bykov
- X Wu
- Z Nahle
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 18/11/2004
- Field of study
Mutations that drive uncontrolled cell-cycle progression are requisite events in tumorigenesis. But evolution has installed in the proliferative programmes of mammalian cells a variety of innate tumour-suppressive mechanisms that trigger apoptosis or senescence, should proliferation become aberrant. These contingent processes rely on a series of sensors and transducers that act in a coordinated network to target the machinery responsible for apoptosis and cell-cycle arrest at different points. Although oncogenic mutations that disable such networks can have profound and varied effects on tumour evolution, they may leave intact latent tumour-suppressive potential that can be harnessed therapeutically
Intrinsic tumour suppression
- Author
- A Aslanian
- A Damalas
- A Egle
- A Kauffmann-Zeh
- A Yang
- AM Pierce
- AW Lin
- B Elenbaas
- B Vogelstein
- C Gaiddon
- C Guerra
- C Scaffidi
- C Yin
- CA Schmitt
- CA Schmitt
- CA Schmitt
- CJ Sherr
- CM Eischen
- CM Eischen
- CW Conn
- D Askew
- D Bergamaschi
- D LeRoith
- D Perez
- D Tolbert
- DA Tuveson
- DR Green
- DR Plas
- DW Felsher
- E de Stanchina
- E White
- EA Conner
- EA Harrington
- EJ Gunther
- Enrique Cepero
- ER Flores
- EW Verschuren
- F Zindy
- F Zindy
- G Christofori
- G Ferbeyre
- G Leone
- G Leone
- Gerard Evan
- GI Evan
- GI Evan
- GP Dimri
- H Harlin
- H Symonds
- HA Rogoff
- HG Wendel
- I Matsumura
- I Vivanco
- J Campisi
- J Grossmann
- J Klefstrom
- J Sage
- J Seoane
- JA Benanti
- JC Wilkinson
- JJ Jacobs
- JL Russell
- JM Grad
- JM Paramio
- JS Fridman
- JW Shay
- K Itahana
- KS Kelly-Spratt
- L Chin
- M Mihara
- M Narita
- M Pearson
- M Senoo
- M Serrano
- M Urist
- MC Raff
- ME Peter
- MJ Liao
- MS Irwin
- MT Hemann
- NN Danial
- R Croxton
- R Sears
- RI Pakunlu
- RW Johnstone
- S Cory
- S Jin
- S Orsulic
- S Pelengaris
- S Pelengaris
- Scott W. Lowe
- SE Moody
- SH Khan
- SM Horner
- SW Lowe
- T Hershko
- T Kamijo
- TA Baudino
- TS Zheng
- VJ Bykov
- X Wu
- Z Nahle
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Multi-target analysis of neoplasms for the evaluation of tumor progression: stochastic approach of biologic processes
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- Diaz-Cano SJ Blanes A, Rubio J, et al.
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- Zlotnik A
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2018
- Field of study