Mortality, incident^# prescriptions for psychotropic medication and consultations with GP after cancer death/index date.

#<p>new courses, not prescribed in the 6 months before the death/index date.</p>*<p>Reference group unexposed.</p>1 5<p>Adjusted for age, gender, number of non-psychotropic prescriptions 6 months prior to cancer death/index date, use of psychotropic medication 6 months prior to cancer death/index date, smoking, alcohol and area deprivation score.</p>2 3 4<p>Adjusted for age, gender number of non-psychotropic prescriptions 6 months prior to cancer death/index date, smoking, alcohol and area deprivation score.</p

Kaplan-Meier survival probabilities in exposed and unexposed groups after cancer death/index date.

<p>Kaplan-Meier survival probabilities in exposed and unexposed groups after cancer death/index date.</p

Description of exposed and unexposed cohorts.

1<p>Expressed as the number who ever had a prescription over the 6 months.</p>2<p>All available records of subjects were searched for information on substance use.</p>3<p>Percentage of women who consumed >14 units of alcohol/week, and men who consumed >21 units/week.</p>4<p>2% of the exposed and 3% of the unexposed did not have data on deprivation.</p

Crude mortality rates within 10 year age bands for the exposed cohort stratified by gender after cancer death.

<p>Crude mortality rates within 10 year age bands for the exposed cohort stratified by gender after cancer death.</p

Prescription of psychotropic medication and consultations with GP over 6 months before cancer death/index date.

*<p>Reference group unexposed.</p>#<p>Adjusted for age, gender, number of non-psychotropic prescriptions, smoking, alcohol and deprivation score.</p

Strobe diagram of participant flow through the study.

<p>Strobe diagram of participant flow through the study.</p

Flow chart for included participants.

Baseline demographic characteristics and risk factor status for the sample are shown in Table 1. South Asian and Black people were on average younger than White people (mean age 69.4 and 69.7 respectively compared to 70.9) and there was a lower percentage of South Asian women (50.8%) compared to White (54.4%) and Black women (56.1%). A greater percentage of South Asian and Black people lived in more deprived areas (18.8% and 35.7% in the most deprived quintile) compared to White people (14.2% in most deprived quintile). Hypertension was most common in Black people (70.7%), followed by South Asians (66.0%) and with the lowest percentage of hypertension in White people (63.0%). The same pattern was seen for obesity– 34.2%, 22.8% and 19.2% in Black, South Asian and White people respectively. Hearing loss was least common in Black people with similar rates in White and South Asian people. Smoking rates were similar in White and South Asian people, but Black people had very low rates of smoking. Excess alcohol use was least common in South Asian people, and most common in White people. Diabetes was three times more common in South Asian people and more than twice as common in Black people than White people. Dyslipidaemia, low HDL and high LDL were all more common in South Asian and Black people than in White people. Sleep disorders were similarly prevalent in White and South Asian people and least common in Black people. Brain injury was recorded with similar frequency across all ethnic groups.</p

Competing risks analysis, adjusted for age, sex and Index of Multiple Deprivation (IMD).

Competing risks analysis, adjusted for age, sex and Index of Multiple Deprivation (IMD).</p

Regression analyses using multiply imputed data, adjusted for age, sex and Index of Multiple Deprivation (IMD).

Regression analyses using multiply imputed data, adjusted for age, sex and Index of Multiple Deprivation (IMD).</p

Baseline demographic characteristics and risk factors of total complete case sample and divided into Black, South Asian and White ethnicity.

Baseline demographic characteristics and risk factors of total complete case sample and divided into Black, South Asian and White ethnicity.</p