Review of Music in the Nineteenth Century, by Walter Frisch

Reviews of: Music in the Nineteenth Century, Walter Frisch. (Western Music in Context, vol. 5). New York: W. W. Norton, 2013. ISBN: 978-0-393-92919-5. Anthology for Music in the Nineteenth Century, Walter Frisch. (Western Music in Context: A Norton History) New York: W. W. Norton, 2013. ISBN: 978-0-393920-178

At the Intersection of Public and Private Musical Life: Brahms’s Op. 51 String Quartets

Brahms’s dedication of his Op. 51 string quartets (1873) to surgeon Theodor Billroth provides a window into Brahms’s music-political views in the 1870s that has heretofore been unexplored by music scholars. Analysis of correspondence, performance traditions, and the scores of these two quartets demonstrates that Brahms chose to align himself and his works with the learned connoisseurs of the domestic chamber-music making tradition, represented by Billroth and his frequent musical soirées. Brahms’s music also shows the influence of Joseph Joachim, his oldest and dearest friend and Europe’s premiere chamber musician. Brahms’s compositional choices in these two works combine public and private musical styles, to offer a touching memorial to earlier composers and friends, and to provide a teachable moment for the musical public

Book Reviews: Classical Music - Unlocking the Masters Series

The following informal guides to Western classical music are briefly reviewed (Amadeus Press): (1) Decoding Wagner: An Invitation to His World of Music Drama, by Thomas May; (2) The Mahler Symphonies, An Owner\u27s Manual, by David Hurwitz; (3) Getting the Most Out of Mozart, the Instrumental Works, by Hurwitz; (4) Getting the Most Out of Mozart, the Vocal Works, by Hurwitz; (5) Exploring Haydn: A Listener\u27s Guide to Music\u27s Boldest Innovator, by Hurwitz; and (6) The Great Instrumental Works, by M. Owen Lee

Investigations Into Methods for the Extraction and Detection of Chlorinated Pesticides in Aquatic Animals.

Methodologies for the extraction and analysis of chlorinated pesticides from aquatic species are reviewed and compared. New multiresidue isolation techniques using Matrix Solid Phase Dispersion (MSPD) are presented for the extraction and subsequent gas chromatographic, electron capture detector determination of 14 chlorinated pesticides ($\alpha$-BHC, $\beta$-BHC, lindane, heptachlor, aldrin, heptachlor epoxide, p,p\sp\prime-DDE, dieldrin, endrin, 4,4\sp\prime-DDD, endrin aldehyde, p,p\sp\prime-DDT, endosulfan sulfate, and methoxychlor) from crayfish (Procambarus clarkii) hepatopancreas, oysters (Crassostrea virginica) and fish muscle tissues. Pureed crayfish hepatopancreata or oysters or fish muscle fillets (0.5-g aliquots) were fortified with the 14 pesticides, plus $\delta$-BHC as an internal standard, before being blended with 2 g of C\sb{18} (octadecylsilyl)-derivatized silica. The C\sb{18}/sample matrix blend and 2 g of activated Florisil comprised an extraction column from which the pesticides were eluted by addition of 8 mL of eluting solvent (acetonitrile or an acetonitrile/methanol blend). Two microliters of the eluate were then directly analyzed by gas chromatography with electron capture detection. Unfortified blank controls were treated similarly. The eluate contained all the pesticide analytes and was free of interfering co-extractants at most fortification levels for the different sample types. Correlation coefficients for the 14 extracted pesticide standard curves (linear regression analysis), average relative percent recoveries over the range of concentrations examined, inter-assay variability and intra-assay variability indicated that the MSPD methodology allowed for the successful extraction and determination of the 14 chlorinated pesticides at levels of 60-2000 ng/g in the sample types tested. Compared to previous methods for the analysis of chlorinated pesticides in aquatic species the techniques and methodology presented here reduce analytical response time, solvent use, solvent waste and disposal and technician exposure. The methods presented are generic and may also prove applicable to the MSPD analysis of a wide range of environmental pollutants. These methods could form the basis for a new approach to pollutant analysis and should be considered as possible replacements for existing methodology utilized by monitoring agencies

Fat Bodies Made Small: A Content Analysis of Fat Literature Classed in Medicine

This study is a content analysis of print materials about fatness classed in Medicine according to the Library of Congress Subject Headings and Classification. Research about the marginalizing power of information systems has centered around gender identity, sexuality, race, non-dominant cultures, and disability, while fat bodies have been largely overlooked. Previous literature on information organization principles, critical cataloging, and fat stigma are reviewed. A qualitative content analysis of fatness in print materials across four class numbers shelved in Davis Library at the University of North Carolina follows. Titles, tables of contents, introductory material, and cover images and summaries are coded for problem and blame frames, attitude, and class. This study brings awareness to the stigmatization of fat bodies by information organization standards and shows the need for new subject headings and class numbers for fat materials.Master of Science in Library Scienc

High-Performance Liquid Chromatography Assay for Moxifloxacin in Brain Tissue and Plasma: Validation in a Pharmacokinetic Study in a Murine Model of Cerebral Listeriosis

Moxifloxacin is a broad-spectrum antibacterial 8-methoxy-fluoroquinolone. In order to evaluate the pharmacokinetic properties of moxifloxacin in mouse plasma and brain tissue, we developed a high-performance liquid chromatography (HPLC) method. This study was based on single-drug delivery, intravenously dosed in a central listeriosis murine model. The method employed a reversed-phase Lichrospher RP-18 with a precolumn (250 × 4.6 mm) and a mobile phase composed of a mixture of acetonitrile, methanol, and citric buffer (pH = 3.5) with sodium dodecyl sulfate and tetrabutylammonium bromide. Fluorescence detection was performed at an excitation wavelength of 290 nm and an emission wavelength of 550 nm. The relative standard deviation of intra- and inter-day assays was <10%. This validated method led to a short retention time (8.0 min) for moxifloxacin. The standard curves were linear from 5–250 μg/L in plasma and from 0.1–2.5 μg/g of brain tissue. The limits of quantification were 5 μg/L in plasma and 0.1 μg/g in brain tissue. The method enabled the detection of systemic antimicrobial in plasma and in CNS in Listeria-infected mice. Injected moxifloxacin passed through the encephalic barrier within a 30 to 60 min after injection time frame. Moxifloxacin pharmacokinetics are modeled in an infected model compared to control mice

MITOMAP: a human mitochondrial genome database—2004 update

MITOMAP (http://www.MITOMAP.org), a database for the human mitochondrial genome, has grown rapidly in data content over the past several years as interest in the role of mitochondrial DNA (mtDNA) variation in human origins, forensics, degenerative diseases, cancer and aging has increased dramatically. To accommodate this information explosion, MITOMAP has implemented a new relational database and an improved search engine, and all programs have been rewritten. System administrative changes have been made to improve security and efficiency, and to make MITOMAP compatible with a new automatic mtDNA sequence analyzer known as Mitomaster

Mitochondrial DNA mutations in human degenerative diseases and aging

AbstractA wide variety of mitochondrial DNA (mtDNA) mutations have recently been identified in degenerative diseases of the brain, heart, skeletal muscle, kidney and endocrine system. Generally, individuals inheriting these mitochondrial diseases are relatively normal in early life, develop symptoms during childhood, mid-life, or old age depending on the severity of the maternally-inherited mtDNA mutation; and then undergo a progressive decline. These novel features of mtDNA disease are proposed to be the product of the high dependence of the target organs on mitochondrial bioenergetics, and the cumulative oxidative phosphorylation (OXPHOS) defect caused by the inherited mtDNA mutation together with the age-related accumulation mtDNA mutations in post-mitotic tissues