The assessment of water use and reuse through reported data: A US case study

Increasing demands for freshwater make it necessary to find innovative ways to extend the life of our water resources, and to manage them in a sustainable way. Indirect water reuse plays a role in meeting freshwater demands but there is limited documentation of it. There is a need to analyze its current status for water resources planning and conservation, and for understanding how it potentially impacts human health. However, the fact that data are archived in discrete uncoordinated databases by different state and federal entities, limits the capacity to complete holistic analysis of critical resources at large watershed scales. Humans alter the water cycle for food production, manufacturing, energy production, provision of potable water and recreation. Ecosystems services are affected at watershed scales but there are also global scale impacts from greenhouse gas emissions enabled by access to cooling, processing and irrigation water. To better document these issues and to demonstrate the utility of such an analysis, we studied the Wabash River Watershed located in the U.S. Midwest. Data for water extraction, use, discharge, and river flow were collected, curated and reorganized in order to characterize the water use and reuse within the basin. Indirect water reuse was estimated by comparing treated wastewater discharges with stream flows at selected points within the watershed. Results show that during the low flow months of July–October, wastewater discharges into the Wabash River basin contributed 82 to 121% of the stream flow, demonstrating that the level of water use and unplanned reuse is significant. These results suggest that intentional water reuse for consumptive purposes such as landscape or agricultural irrigation could have substantial ecological impacts by diminishing stream flow during vulnerable low flow periods

Almost commuting unitary matrices related to time reversal

The behavior of fermionic systems depends on the geometry of the system and the symmetry class of the Hamiltonian and observables. Almost commuting matrices arise from band-projected position observables in such systems. One expects the mathematical behavior of almost commuting Hermitian matrices to depend on two factors. One factor will be the approximate polynomial relations satisfied by the matrices. The other factor is what algebra the matrices are in, either the matrices over A for A the real numbers, A the complex numbers or A the algebra of quaternions. There are potential obstructions keeping k-tuples of almost commuting operators from being close to a commuting k-tuple. We consider two-dimensional geometries and so this obstruction lives in KO_{-2}(A). This obstruction corresponds to either the Chern number or spin Chern number in physics. We show that if this obstruction is the trivial element in K-theory then the approximation by commuting matrices is possible.Comment: 33 pages, 2 figures. In version 2 some formulas have been corrected and some proofs have been rewritten to improve the expositio

Dynamic and volumetric variables reliably predict fluid responsiveness in a porcine model with pleural effusion

Background: The ability of stroke volume variation (SVV), pulse pressure variation (PPV) and global end-diastolic volume (GEDV) for prediction of fluid responsiveness in presence of pleural effusion is unknown. The aim of the present study was to challenge the ability of SVV, PPV and GEDV to predict fluid responsiveness in a porcine model with pleural effusions. Methods: Pigs were studied at baseline and after fluid loading with 8 ml kg−1 6% hydroxyethyl starch. After withdrawal of 8 ml kg−1 blood and induction of pleural effusion up to 50 ml kg−1 on either side, measurements at baseline and after fluid loading were repeated. Cardiac output, stroke volume, central venous pressure (CVP) and pulmonary occlusion pressure (PAOP) were obtained by pulmonary thermodilution, whereas GEDV was determined by transpulmonary thermodilution. SVV and PPV were monitored continuously by pulse contour analysis. Results: Pleural effusion was associated with significant changes in lung compliance, peak airway pressure and stroke volume in both responders and non-responders. At baseline, SVV, PPV and GEDV reliably predicted fluid responsiveness (area under the curve 0.85 (p<0.001), 0.88 (p<0.001), 0.77 (p = 0.007). After induction of pleural effusion the ability of SVV, PPV and GEDV to predict fluid responsiveness was well preserved and also PAOP was predictive. Threshold values for SVV and PPV increased in presence of pleural effusion. Conclusions: In this porcine model, bilateral pleural effusion did not affect the ability of SVV, PPV and GEDV to predict fluid responsiveness

Observation of anomalous decoherence effect in a quantum bath at room temperature

Decoherence of quantum objects is critical to modern quantum sciences and technologies. It is generally believed that stronger noises cause faster decoherence. Strikingly, recent theoretical research discovers the opposite case for spins in quantum baths. Here we report experimental observation of the anomalous decoherence effect for the electron spin-1 of a nitrogen-vacancy centre in high-purity diamond at room temperature. We demonstrate that under dynamical decoupling, the double-transition can have longer coherence time than the single-transition, even though the former couples to the nuclear spin bath as twice strongly as the latter does. The excellent agreement between the experimental and the theoretical results confirms the controllability of the weakly coupled nuclear spins in the bath, which is useful in quantum information processing and quantum metrology.Comment: 22 pages, related paper at http://arxiv.org/abs/1102.557

The research journey: Travels across the idiomatic and axiomatic toward a better understanding of complexity

In this paper, seven researchers reflect on the journeys their research projects have taken when they engage with and synthesize complex problems. These journeys embody an adaptive approach to tackling problems characterized by their interconnectedness and emergence, and that transcend traditional units of analysis such as ecosystems. In this paper we argue that making such a process deliberate and explicit will help researchers better combine different research paradigms such as expert-driven and participant-directed work, thus resulting in both broad explanations and specific phenomenon; research tensions traditionally defined as oppositional must be approached as complimentary. This paper includes researchers. personal journeys as they dealt with the emergent properties of complex problems and participant involvement. This paper argues that that research journey should be more than accidental but is a methodological necessity and should guide the theoretical and practical approaches to complex problems

Application of a low cost array-based technique — TAB-Array — for quantifying and mapping both 5mC and 5hmC at single base resolution in human pluripotent stem cells

Abstract5-hydroxymethylcytosine (5hmC), an oxidized derivative of 5-methylcytosine (5mC), has been implicated as an important epigenetic regulator of mammalian development. Current procedures use DNA sequencing methods to discriminate 5hmC from 5mC, limiting their accessibility to the scientific community. Here we report a method that combines TET-assisted bisulfite conversion with Illumina 450K DNA methylation arrays for a low-cost high-throughput approach that distinguishes 5hmC and 5mC signals at base resolution. Implementing this approach, termed “TAB-array”, we assessed DNA methylation dynamics in the differentiation of human pluripotent stem cells into cardiovascular progenitors and neural precursor cells. With the ability to discriminate 5mC and 5hmC, we identified a large number of novel dynamically methylated genomic regions that are implicated in the development of these lineages. The increased resolution and accuracy afforded by this approach provides a powerful means to investigate the distinct contributions of 5mC and 5hmC in human development and disease

A first estimate of triply heavy baryon masses from the pNRQCD perturbative static potential

Within pNRQCD we compute the masses of spin-averaged triply heavy baryons using the now-available NNLO pNRQCD potentials and three-body variational approach. We focus in particular on the role of the purely three-body interaction in perturbation theory. This we find to be reasonably small and of the order 25 MeV Our prediction for the Omega_ccc baryon mass is 4900(250) in keeping with other approaches. We propose to search for this hitherto unobserved state at B factories by examining the end point of the recoil spectrum against triple charm.Comment: 18 figures, 21 page

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types.

Large-scale collections of induced pluripotent stem cells (iPSCs) could serve as powerful model systems for examining how genetic variation affects biology and disease. Here we describe the iPSCORE resource: a collection of systematically derived and characterized iPSC lines from 222 ethnically diverse individuals that allows for both familial and association-based genetic studies. iPSCORE lines are pluripotent with high genomic integrity (no or low numbers of somatic copy-number variants) as determined using high-throughput RNA-sequencing and genotyping arrays, respectively. Using iPSCs from a family of individuals, we show that iPSC-derived cardiomyocytes demonstrate gene expression patterns that cluster by genetic background, and can be used to examine variants associated with physiological and disease phenotypes. The iPSCORE collection contains representative individuals for risk and non-risk alleles for&nbsp;95% of SNPs associated with human phenotypes through genome-wide association studies. Our study demonstrates the utility of iPSCORE for examining how genetic variants influence molecular and physiological traits in iPSCs and derived cell lines

Using Land-Based Surveys to Assess Sea Duck Abundance and Behavior in Nearshore Waters of Southern New England, USA

Nearshore waters provide very important habitat for sea ducks (Tribe Mergini) during migration and winter, but gathering information on sea duck use of shallow nearshore waters is challenging because traditional aerial and boat-based surveys are expensive, are usually conducted infrequently, and are often not feasible near the coast. The objective of this study was to use land-based surveys to characterize spatiotemporal variation in the abundance and behavior (e.g., foraging, flying) of Common Eider (Somateria mollissima) and scoters (Melanitta spp.) in nearshore waters of southern New England. Surveys (60–120 min per survey, n = 1,044 surveys) were conducted throughout the day from February 2009 to July 2010 to assess diurnal and seasonal variation in sea duck behavior and spatial distribution at nine sites in southern Rhode Island. The density of sea ducks resting or foraging on the water exhibited little diurnal variation, whereas flight activity dramatically increased nearer to sunrise. Sea duck densities and passage rates (individuals/km2/hr) peaked during migration periods from October through November and February through April, although there were important seasonal differences between sites. For example, the highest densities of Common Eider during fall were in a protected estuary, whereas abundance of scoters during fall was greater at a coastal headland. The relative activity of Common Eider on the water and in flight was similar among sites, whereas scoters exhibited highly variable activity among sites, particularly during winter and spring. The spatiotemporal patterns in abundance and behavior of sea ducks in nearshore waters that we detected using land-based surveys provides essential, complementary information to that available from other types of waterfowl and seabird surveys in southern New England

Sixty Years of Modern Human Origins in the American Anthropological Association

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65197/1/aa.2003.105.1.89.pd