2,439 research outputs found
Exploring Special Relative Locality with deSitter momentum-space
Relative Locality is a recent approach to the quantum-gravity problem which
allows to tame nonlocality effects which may rise in some models which try to
describe Planck-scale physics. I here explore the effect of Relative Locality
on basic special-relativistic phenomena. In particular I study the deformations
due to Relative Locality of special-relativistic transformation laws for
momenta at all orders in the rapidity parameter . I underline how those
transformations also define the RL characteristic (momentum-dependent)
invariant metric. I focus my analysis on the well studied deSitter
momentum-space framework and I investigate the differences and similarities
between this model and Special Relativity, from the definition of the boost
parameter to a first discussion of transverse-effects characteristic
of Relative Locality on clocks observables.Comment: 9 pages, 2 figure
Rainbow metric formalism and Relative Locality
This proceeding is based on a talk prepared for the XIII Marcell Grossmann
meeting. We summarise some results of work in progress in collaboration with
Giovanni Amelino-Camelia about momentum dependent (Rainbow) metrics in a
Relative Locality framework and we show that this formalism is equivalent to
the Hamiltonian formalization of Relative Locality obtained in arXiv:1102.4637.Comment: appears in Proceedings of the 13th Marcell Grossmann meeting on
General Relativity, World Scientific, Singapore, (2014
Quantum Gravity phenomenology and metric formalism
In this proceedings for the MG14 conference, we discuss the construction of a
phenomenology of Planck-scale effects in curved spacetimes, underline a few
open issues and describe some perspectives for the future of this research
line
The mechanics of active clays circulated by salts, acids and bases: Comprehensive version
An elastic-plastic model that accounts for electro-chemo-mechanical couplings in clays, due to the presence of dissolved salts and acids and bases, is developed here for the first time. To the authors' best knowledge, no other comprehensive project to embody the effects of pH in the elastic-plastic behavior of geomaterials has been attempted so far. Chemically sensitive clays are viewed as two-phase multi-species saturated porous media circulated by an electrolyte. The developments are embedded in the framework of the thermodynamics of multi-phase multi-species porous media. This approach serves to structure the model, and to motivate constitutive equations. The present extension capitalize upon the earlier developments by Gajo et al. [2002] and Gajo and Loret [2004], which were devoted to modeling chemo-mechanical couplings at constant pH. Four transfer mechanisms between the solid and fluid phases are delineated in the model: (1) hydration, (2) ion exchange, (3) acidification, (4) alkalinization. Thus all fundamental exchanges at particle level are fully taken into account. Only mineral dissolution is neglected, since experimental observations indicates a negligible role of mineral dissolution for active clays at room temperature. In particular, the newly considered mechanisms of acidification and alkalinization directly affect the electrical charge of clay particles and thus have a key role in the electro-chemo-mechanical couplings. These four mechanisms are seen as controlling both elastic and elasto-plastic behaviors. Depending on concentrations and ionic affinities to the clay mineral, these mechanisms either compete or cooperate to modify the compressibility and strength of the clay and may induce swelling (volume expansion) or shrinking (volume contraction). The framework is rich enough to allow for the simulations of recently performed laboratory experiments on clay samples submitted to intertwined mechanical and chemical loading programmes, involving large changes in ionic strengths and pH. This work is the comprehensive version of the paper published on the Journal of the Mechanics and Physics of Solids, 55(8), 1762-180
Dual redshift on Planck-scale-curved momentum spaces
Several approaches to the investigation of the quantum-gravity problem have
provided "theoretical evidence" of a role for the Planck scale in
characterizing the geometry of momentum space. One of the main obstructions for
a full exploitation of this scenario is the understanding of the role of the
Planck-scale-curved geometry of momentum space in the correlations between
emission and detection times, the "travel times" for a particle to go from a
given emitter to a given detector. These travel times appear to receive
Planck-scale corrections for which no standard interpretation is applicable,
and the associated implications for spacetime locality gave rise to the notion
of "relative locality" which is still in the early stages of investigation. We
here show that these Planck-scale corrections to travel times can be described
as "dual redshift" (or "lateshift"): they are manifestations of momentum-space
curvature of the same type already known for ordinary redshift produced by
spacetime curvature. In turn we can identify the novel notion of "relative
momentum-space locality" as a known but under-appreciated feature associated to
ordinary redshift produced by spacetime curvature, and this can be described in
complete analogy with the relative spacetime locality that became of interest
in the recent quantum-gravity literature. We also briefly comment on how these
findings may be relevant for an approach to the quantum-gravity problem
proposed by Max Born in 1938 and centered on Born duality.Comment: 13 pages, LaTe
Hamilton Geometry - Phase Space Geometry from Modified Dispersion Relations
Quantum gravity phenomenology suggests an effective modification of the
general relativistic dispersion relation of freely falling point particles
caused by an underlying theory of quantum gravity. Here we analyse the
consequences of modifications of the general relativistic dispersion on the
geometry of spacetime in the language of Hamilton geometry. The dispersion
relation is interpreted as the Hamiltonian which determines the motion of point
particles. It is a function on the cotangent bundle of spacetime, i.e. on phase
space, and determines the geometry of phase space completely, in a similar way
as the metric determines the geometry of spacetime in general relativity. After
a review of the general Hamilton geometry of phase space we discuss two
examples. The phase space geometry of the metric Hamiltonian
and the phase space geometry of the first order q-de
Sitter dispersion relation of the form which is suggested from quantum gravity phenomenology. We
will see that for the metric Hamiltonian the geometry of phase space is
equivalent to the standard metric spacetime geometry from general relativity.
For the q-de Sitter Hamiltonian the Hamilton equations of motion for
point particles do not become autoparallels but contain a force term, the
momentum space part of phase space is curved and the curvature of spacetime
becomes momentum dependent.Comment: 6 page
Quantum-gravity-induced dual lensing and IceCube neutrinos
Momentum-space curvature, which is expected in some approaches to the
quantum-gravity problem, can produce dual redshift, a feature which introduces
energy dependence of the travel times of ultrarelativistic particles, and dual
lensing, a feature which mainly affects the direction of observation of
particles. In our recent arXiv:1605.00496 we explored the possibility that dual
redshift might be relevant in the analysis of IceCube neutrinos, obtaining
results which are preliminarily encouraging. Here we explore the possibility
that also dual lensing might play a role in the analysis of IceCube neutrinos.
In doing so we also investigate issues which are of broader interest, such as
the possibility of estimating the contribution by background neutrinos and some
noteworthy differences between candidate "early neutrinos" and candidate "late
neutrinos".Comment: In this version V2 we give a definition of variation probability
which could be considered in alternative to the notion of variation
probability already introduced in version V1; both notions of variation
probability are contemplated in the data analysis. arXiv admin note: text
overlap with arXiv:1605.0049
Hamilton geometry: Phase space geometry from modified dispersion relations
We describe the Hamilton geometry of the phase space of particles whose
motion is characterised by general dispersion relations. In this framework
spacetime and momentum space are naturally curved and intertwined, allowing for
a simultaneous description of both spacetime curvature and non-trivial momentum
space geometry. We consider as explicit examples two models for Planck-scale
modified dispersion relations, inspired from the -de Sitter and
-Poincar\'e quantum groups. In the first case we find the expressions
for the momentum and position dependent curvature of spacetime and momentum
space, while for the second case the manifold is flat and only the momentum
space possesses a nonzero, momentum dependent curvature. In contrast, for a
dispersion relation that is induced by a spacetime metric, as in General
Relativity, the Hamilton geometry yields a flat momentum space and the usual
curved spacetime geometry with only position dependent geometric objects.Comment: 32 pages, section on quantisation of the theory added, comments on
additin of momenta on curved momentum spaces extende
Rainbows without unicorns: Metric structures in theories with Modified Dispersion Relations
Rainbow metrics are a widely used approach to metric formalism for theories
with Modified Dispersion Relations. They have had a huge success in the Quantum
Gravity Phenomenology literature, since they allow to introduce
momentum-dependent spacetime metrics into the description of systems with
Modified Dispersion Relation. In this paper, we introduce the reader to some
realizations of this general idea: the original Rainbow metrics proposal, the
momentum-space-inspired metric, the standard Finsler geometry approach and our
alternative definition of a four-velocity-dependent metric with a massless
limit. This paper aims to highlight some of their properties and how to
properly describe their relativistic realizations.Comment: 10 pages. Discussion on the role of connections was added. Matches
published versio
The role of epithelial-to-mesenchymal plasticity in ovarian cancer progression and therapy resistance
Ovarian cancer is the most lethal of all gynecologic malignancies and the eighth leading cause of cancer-related deaths among women worldwide. The main reasons for this poor prognosis are late diagnosis; when the disease is already in an advanced stage, and the frequent development of resistance to current chemotherapeutic regimens. Growing evidence demonstrates that apart from its role in ovarian cancer progression, epithelial-to-mesenchymal transition (EMT) can promote chemotherapy resistance. In this review, we will highlight the contribution of EMT to the distinct steps of ovarian cancer progression. In addition, we will review the different types of ovarian cancer resistance to therapy with particular attention to EMT-mediated mechanisms such as cell fate transitions, enhancement of cancer cell survival, and upregulation of genes related to drug resistance. Preclinical studies of anti-EMT therapies have yielded promising results. However, before anti-EMT therapies can be effectively implemented in clinical trials, more research is needed to elucidate the mechanisms leading to EMT-induced therapy resistance
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