4 research outputs found

    Additional file 1: Figures S1–S5. of SETDB1 prevents TET2-dependent activation of IAP retroelements in naïve embryonic stem cells

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    Figure S1. SETDB1 regulates ERV silencing in naïve ESCs. Figure S2. Removal of TET2 dampens SETDB1-mediated IAP activation in naïve cells. Figure S3. SETDB1-mediated IAP activation is not linked to DNA methylation changes. Figure S4. SETDB1 depletion does not lead to DNA methylation changes. Figure S5. TET2 activity is associated with loss of H4R3me2s at IAPs. (PDF 828 kb

    Additional file 6: of IL-4 orchestrates STAT6-mediated DNA demethylation leading to dendritic cell differentiation

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    Relationship between methylation and expression changes in MAC and DC differentiation. “Poised” genes are those undergoing DNA methylation changes at the differentiation stage and expression changes only at the activation stage. (XLSX 640 kb
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