How to Work With Public Opinion Research: A Guide for Human Rights and Civil Liberties Advocates and Their Funders

Presents arguments and tools for integrating public opinion research into communications work. Includes case studies, research methods, consultant information, and a guide to help grantmakers evaluate grant proposals to conduct public opinion research

One Million Police Hours: Making 440,000 Marijuana Possession Arrests in New York City

A new report released today documents the astonishing number of hours the New York Police Department has spent arresting and processing hundreds of thousands of people for low-level misdemeanor marijuana possession arrests during Mayor Bloomberg's tenure. The report finds that NYPD used approximately 1,000,000 hours of police officer time to make 440,000 marijuana possession arrests over 11 years. These are hours that police officers might have otherwise have spent investigating and solving serious crimes.The report was prepared by Dr. Harry Levine, Professor of Sociology at Queens College and recognized expert on marijuana possession arrests, at the request of members of the New York City Council and the New York State Legislature.Additionally, the report estimates that the people arrested by NYPD for marijuana possession have spent 5,000,000 hours in police custody over the last decade. The report includes a compendium of quotes from academics, journalists, law enforcement professionals and elected officials attesting to the wastefulness, consequences and racial disparities inherent in these arrests

Toward a New Federal Right to Privacy

Drug testing in the American workplace is the new panacea

A New Sensibility: An Analysis of Public Opinion Research on Attitudes Towards Crime and Criminal Justice Policy

This report is based on a review of more than 50 public opinion surveys and polls, most of them conducted between June 2014 and June 2016. Many of them are based on state rather than national samples, reflecting the fact that most of the action in terms of policy reform has been at the state level. The research included covers American attitudes towards a range of policy issues that comprise the criminal justice reform agenda

A prospective trial comparing FDG-PET/CT and CT to assess tumor response to cetuximab in patients with incurable squamous cell carcinoma of the head and neck

Computed tomography (CT), the standard method to assess tumor response to cetuximab in incurable squamous cell carcinoma of the head and neck (SCCHN), performs poorly as judged by the disparity between high disease control rate (46%) and short time to progression (TTP) (70 days). F-18 fluorodeoxyglucose positron emission tomography (FDG-PET)/CT is an alternative method to assess tumor response. The primary objective of this prospective trial was to evaluate the metabolic response of target lesions, assessed as the change in maximum standardized uptake value (SUV(max)) on FDG-PET/CT before and after 8 weeks (cycle 1) of cetuximab. Secondary objectives were to compare tumor response by CT (RECIST 1.0) and FDG-PET/CT (EORTC criteria) following cycle 1, and determine TTP with continued cetuximab administration in patients with disease control by CT after cycle 1 but stratified for disease control or progression by FDG-PET/CT. Among 27 patients, the mean percent change of SUV(max) of target lesions after cycle 1 was −21% (range: +72% to −81%); by FDG-PET/CT, partial response (PR)/stable disease (SD) occurred in 15 patients (56%) and progression in 12 (44%), whereas by CT, PR/SD occurred in 20 (74%) and progression in 7 (26%). FDG-PET/CT and CT assessments were discordant in 14 patients (P = 0.0029) and had low agreement (κ = 0.30; 95% confidence interval [CI]: 0.12, 0.48). With disease control by CT after cycle 1, median TTP was 166 days (CI: 86, 217) if the FDG-PET/CT showed disease control and 105 days (CI: 66, 159) if the FDG-PET/CT showed progression (P < 0.0001). Median TTP of the seven patients whose post cycle 1 CT showed progression compared to the 12 whose FDG-PET/CT showed progression were similar (53 [CI: 49, 56] vs. 61 [CI: 50, 105] days, respectively). FDG-PET/CT may be better than CT in assessing benefit of cetuximab in incurable SCCHN

Mechanical Bonds and Topological Effects in Radical Dimer Stabilization

While mechanical bonding stabilizes tetrathiafulvalene (TTF) radical dimers, the question arises: what role does topology play in catenanes containing TTF units? Here, we report how topology, together with mechanical bonding, in isomeric [3]- and doubly interlocked [2]catenanes controls the formation of TTF radical dimers within their structural frameworks, including a ring-in-ring complex (formed between an organoplatinum square and a {2+2} macrocyclic polyether containing two 1,5-dioxynaphthalene (DNP) and two TTF units) that is topologically isomeric with the doubly interlocked [2]catenane. The separate TTF units in the two {1+1} macrocycles (each containing also one DNP unit) of the isomeric [3]catenane exhibit slightly different redox properties compared with those in the {2+2} macrocycle present in the [2]catenane, while comparison with its topological isomer reveals substantially different redox behavior. Although the stabilities of the mixed-valence (TTF2)^(•+) dimers are similar in the two catenanes, the radical cationic (TTF^(•+))_2 dimer in the [2]catenane occurs only fleetingly compared with its prominent existence in the [3]catenane, while both dimers are absent altogether in the ring-in-ring complex. The electrochemical behavior of these three radically configurable isomers demonstrates that a fundamental relationship exists between topology and redox properties

Roma de profundis: Post-economic miracle Rome and the films of Dario Argento (1970–1982)

Abstract not available

Synthesis of a D-3-symmetric "trefoil" knotted cyclophane

A D-3-symmetric knotted cyclophane, with a subgraph of trefoil topology, was synthesized by cyclization of a D-3-symmetric scaffold. Control of configuration at the three metal-based stereocenters arises from a bascule/pivot mechanism.</p