Rhodium(II)-Catalyzed Formal [3 + 2] Cycloaddition of <i>N</i>‑Sulfonyl-1,2,3-triazoles with Isoxazoles: Entry to Polysubstituted 3‑Aminopyrroles

A novel rhodium­(II)-catalyzed formal [3 + 2] cycloaddition of <i>N</i>-sulfonyl-1,2,3-triazoles with isoxazoles has been achieved that provides an efficient method for the synthesis of polysubstituted 3-aminopyrrole derivatives. An operationally simple one-pot synthesis of the titled compounds from terminal alkynes, tosyl azide, and isoxazoles was also developed. The presented reaction affords an illustrative example of employing 1,2,3-triazoles as the [2C]-component in relevant cycloaddition reactions

Unadjusted and adjusted relationship of hypertension to urban/rural.

<p>* Adjusted for gender, region, age, education level, retired status, marital status, BMI, Family of hypertension.</p

Factors associated with the prevalence of hypertension in urban and rural residents by multivariate logistic regression models.

<p>Factors associated with the prevalence of hypertension in urban and rural residents by multivariate logistic regression models.</p

Distribution and demographic characteristics of the study population.

<p>Distribution and demographic characteristics of the study population.</p