8 research outputs found
Flutter Analysis of Long Span Suspension Bridge Considering Aerostatic Torsional Angles
This paper was reviewed and accepted by the APCWE-IX Programme Committee for Presentation at the 9th Asia-Pacific Conference on Wind Engineering, University of Auckland, Auckland, New Zealand, held from 3-7 December 2017
Table_2_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.XLSX
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Image_3_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.TIFF
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Image_2_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.TIFF
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Image_1_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.TIFF
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Table_1_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.XLSX
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Image_4_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.TIFF
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p
Table_3_Effect of basal metabolic rate on osteoporosis: A Mendelian randomization study.XLSX
PurposeBasal metabolic rate may play a key role in the pathogenesis and progression of osteoporosis. We performed Mendelian random analysis to evaluate the causal relationship between basal metabolic rate and osteoporosis.MethodsInstrumental variables for the basal metabolic rate were selected. We used the inverse variance weighting approach as the main Mendelian random analysis method to estimate causal effects based on the summary-level data for osteoporosis from genome-wide association studies.ResultsA potential causal association was observed between basal metabolic rate and risks of osteoporosis (odds ratio = 0.9923, 95% confidence interval: 0.9898β0.9949; P = 4.005e β 09). The secondary MR also revealed that BMR was causally associated with osteoporosis (odds ratio = 0.9939, 95% confidence interval: 0.9911β0.9966; P = 1.038e β 05). The accuracy and robustness of the findings were confirmed using sensitivity tests.ConclusionBasal metabolic rate may play a causal role in the development of osteoporosis, although the underlying mechanisms require further investigation.</p