47,983 research outputs found
The Mayflies (Ephemeroptera) of Tennessee, With a Review of the Possibly Threatened Species Occurring Within the State
One hundred and forty-three species of mayflies are reported from the state of Tennessee. Sixteen species (Ameletus cryptostimulus, Choroterpes basalis, Baetis virile, Ephemera blanda, E. simulans, Ephemerella berneri, Heterocloeon curiosum, H. petersi, Labiobaetis ephippiatus, Leptophlebia bradleyi, Macdunnoa brunnea, Paraleptophlebia assimilis, P. debilis, P. mollis, Rhithrogenia pellucida and Siphlonurus mirus) are reported for the first time. Rare and vulnerable species occurring in the state are also discussed. This represents the first comprehensive statewide list of mayflies for Tennessee
Investment Patterns and Financial Leverage
This study Investigates the influence of the type of investment opportunities facing a firm on its choice of capital structure. It is shown that the more discretionary investment opportunities a firm faces,the lower its financial leverage. Inclusion of other possible determinants of capital structure, such as availability of internal funds, tax effects and risk, while significant, do not affect the importance of discretionary investment. The evidence supports (1) the existence of a moral bazzard problem which inversely relates risky debt and discretionary investment choice, and (2) a desire by most firms to use sources of internal funds prior to entering the capital market.
Uncoupling of p97 ATPase activity has a dominant negative effect on protein extraction
p97 is a highly abundant, homohexameric AAA+ ATPase that performs a variety of essential cellular functions. Characterized as a ubiquitin-selective chaperone, p97 recognizes proteins conjugated to K48-linked polyubiquitin chains and promotes their removal from chromatin and other molecular complexes. Changes in p97 expression or activity are associated with the development of cancer and several related neurodegenerative disorders. Although pathogenic p97 mutations cluster in and around p97's ATPase domains, mutant proteins display normal or elevated ATPase activity. Here, we show that one of the most common p97 mutations (R155C) retains ATPase activity, but is functionally defective. p97-R155C can be recruited to ubiquitinated substrates on chromatin, but is unable to promote substrate removal. As a result, p97-R155C acts as a dominant negative, blocking protein extraction by a similar mechanism to that observed when p97's ATPase activity is inhibited or inactivated. However, unlike ATPase-deficient proteins, p97-R155C consumes excess ATP, which can hinder high-energy processes. Together, our results shed new insight into how pathogenic mutations in p97 alter its cellular function, with implications for understanding the etiology and treatment of p97-associated diseases
Macromolecular separation through a porous surface
A new technique for the separation of macromolecules is proposed and
investigated. A thin mesh with pores comparable to the radius of gyration of a
free chain is used to filter chains according to their length. Without a field
it has previously been shown that the permeability decays as a power law with
chain length. However by applying particular configurations of pulsed fields,
it is possible to have a permeability that decays as an exponential. This
faster decay gives much higher resolution of separation. We also propose a
modified screen containing an array of holes with barb-like protrusions running
parallel to the surface. When static friction is present between the
macromolecule and the protrusion, some of the chains get trapped for long
durations of time. By using this and a periodic modulation of an applied
electric field, high resolution can be attained.Comment: 18 pages latex, 6 postscript figures, using psfi
Search for and strangeonium-like structures
Theoretically, it has been presumed from an effective Lagrangian calculation
that there could exist two charged strangeonium-like molecular states
and , with and
configurations respectively. In the framework of QCD sum rules, we predict that
masses of () and ()
are and respectively, which are both above
their respective two meson thresholds. We suggest to put in practice the search
for these two charged strangeonium-like structures in future experiments.Comment: 7 pages, 4 eps figures; the version accepted for publication in PRD.
arXiv admin note: text overlap with arXiv:1203.070
Non-Gaussian Features of Transmitted Flux of QSO's Ly Absorption: Intermittent Exponent
We calculate the structure function and intermittent exponent of the 1.) Keck
data, which consists of 29 high resolution, high signal to noise ratio (S/N)
QSO Ly absorption spectra, and 2.)the Ly forest simulation
samples produced via the pseudo hydro scheme for the low density cold dark
matter (LCDM) model and warm dark matter (WDM) model with particle mass
and 1000 eV. These two measures detect not only
non-gaussianities, but also the type of non-gaussianty in the the field. We
find that, 1.) the structure functions of the simulation samples are
significantly larger than that of Keck data on scales less than about 100
h kpc, 2.) the intermittent exponent of the simulation samples is more
negative than that of Keck data on all redshifts considered, 3.) the
order-dependence of the structure functions of simulation samples are closer to
the intermittency of hierarchical clustering on all scales, while the Keck data
are closer to a lognormal field on small scales. These differences are
independent of noise and show that the intermittent evolution modeled by the
pseudo-hydro simulation is substantially different from observations, even
though they are in good agreement in terms of second and lower order
statistics. (Abridged)Comment: 17 pages, 13 figures. Accepted by Ap
Evolution of Nuclear Shell Structure due to the Pion Exchange Potential
The evolution of nuclear shell structure is investigated for the first time
within density-dependent relativistic Hartree-Fock theory and the role of
-exchange potential is studied in detail. The energy differences between
the neutron orbits \Lrb{\nu1h_{9/2},\nu 1i_{13/2}} in the N=82 isotones and
between the proton ones \Lrb{\pi1g_{7/2},\pi1h_{11/2}} in the Z=50 isotopes
are extracted as a function of neutron excess . A kink around for
the N=82 isotones is found as an effect resulting from pion correlations. It is
shown that the inclusion of -coupling plays a central role to provide
realistic isospin dependence of the energy differences. In particular, the
tensor part of the -coupling has an important effect on the characteristic
isospin dependence observed in recent experiments.Comment: 4 pages and 4 figure
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