Association between work related stress and health related quality of life: the impact of socio-demographic variables. A cross sectional study in a region of central Italy

The aim of this work is investigate relationship between health-related quality of life and work-related stress and the impact of gender, education level, and age on this relationship. A cross-sectional study was conducted among workers of various setting in Rome and Frosinone. Work-related stress was measured with a demand-control questionnaire and health-related functioning by SF (short form)-12 health survey. There were 611 participants. Men reported high mental composite summary (MCS) and physical composite summary (PCS). In multivariate analysis age, gender (p < 0.001) and job demand (0.045) predicted low PCS. Low MCS predicted poor PCS. Job demand and educational level resulted negatively associated with MCS. In an analysis stratified for age, gender, and educational level, gender and age resulted effect modifier for MCS, gender and education level for PCS. In women increase of decision latitude predict (p = 0.001) an increase in MCS; a low job demand predict high MCS in male (p ≤ 0.001). In younger workers, a lower level of job demand predicted high MCS (<0.001). For PCS, gender and education level resulted effect modifier. In women, high decision latitude predicted higher PCS (p = 0.001) and lower level of job demand results in higher PCS (p ≤ 0.001). Higher educational level resulted predictor of low PCS. Management of risk about work-related stress should consider socio-demographic factors

Predictive factors of fetal macrosomia.

BACKGROUND: Fetal macrosomia is a condition which may increase the risk of mechanical and/or dynamic problems for the parturient. In the past, we have demonstrated that in more than half of the cases it is not possible to exclude a contribution of maternal pathology to the determination of fetal-macrosomia. The aim of this work is to verify whether our more recent experience regarding predictive factors of fetal macrosomia shows some noteworthy novelty. METHODS: The study was retrospectively carried out on pregnant women who, during the period January 1994-February 1996, delivered babies weighing at least 4 kg at the Midwifery School of Camerino. With regard to the frequency of the main risk factors of fetal macrosomia described in scientific literature, the sample was compared with a control group randomly selected. RESULTS: Advanced gestational age at the time of delivery, parental tallness, maternal overweight/obesity, gestational glucidic dysmetabolism, a distance between pubis and uterine fundus of at least 34 cm, male sex of the unborn child have proved to be predictive factors of fetal macrosomia. CONCLUSIONS: The differences in comparison with the past, on the other hand altogether negligible, are the consequence of changes in the management of some obstetric situations

Systematic review of the literature regarding the risk of mortality, cancer and cardiovascular diseases in professional drivers

BACKGROUND: Possible ill- health effects of exposures incurred by professional drivers have been reported by several studies with more or less statistically significant results, and continue to be debated in the medical literature. The aim of the present study was to review the existing literature regarding the association between working as a professional driver, mortality, cancer and cardio-vascular diseases. METHODS: The authors considered studies published until May 2012. The literature review was conducted by searching PubMed and EMBASE and using the following research entries: "professional drivers", "mortality", "cancer", "cardiovascular diseases", "health risks", "air-pollution" and "urban air". RESULTS: Of 1,497 studies reviewed, 25 were included in the final analysis. Nine studies were found assessing mortality. Of these, one study indicated that professional drivers had a significantly increased risk for all- cause mortality compared to the general population (Standardised Mortality Ratio, SMR=1.15); five studies indicated a significantly higher risk of lung cancer mortality (SMR ranged 1.16 and 2.12). Seven studies evaluating cardio-vascular diseases focused on myocardial infarction. These reported a higher risk in professional drivers with respect to controls, with crude Odds Ratios (OR) between 1.66 and 3.3, Relative Risks (RR) ranging from 1.19 to 1.6. In five of the above studies, potential confounders were considered. Five of 11 studies reported a statistically significant increased risk of lung cancer in professional drivers with respect to the general population or to other workers, with ORs included between 1.21 and 1.85, and RRs between 1.2 and 1.4. CONCLUSIONS: The reviewed studies had many limitations, such as poor exposure assessment and lack of information on relevant confounders. In addition, heterogeneity in the studies led to problems in summarizing the results. Despite this, study findings suggest the existence of an association between this professional activity and risk for lung cancer and cardiovascular diseases

Pleural plaque fibrosis: a clinical case

Abstract A recent case of pleural plaques fibrosis in a worker exposed since 20 years to asbestos induced us to report our experience. A 52-year-old man was seen because of chest multiple opaques of soft tissue density without any symptoms. The CT-scan of thorax with i.v. contrast showed multiple lesions of diameter 0.5-4 cm on the posterolateral pleura bilaterally. FNAB of one lesion CT guided was not diagnostic. The pleural biopsy obtained at surgical exploration showed hyaline tissue, avascular, almost acellular, with calcifications and inflammation of low grade. The pleural plaques are generally multifocal and bilateral. They usually affect the parietal pleura. The connection between asbestos and plaques is firmly established. The pathogenesis is not well known. The pleural plaques fibrosis is a benign disease and a very common manifestation of asbestos exposure; it is not related to mesothelioma and it does not need any treatment. Because of the lack of symptoms it must be searched for in high risk subjects

PGF2 and the induction of the trial of labor. The prognostic value of uterine contractions.

BACKGROUND: Uterine contractions during the first hour following intracervical application of dinoprostone would show the myometrial sensitivity to prostaglandins E2 (PGE2) and could be a good practical marker of the real prospects of success of an attempt to induce labor according to the above mentioned modalities. The verification of such an hypothesis is the principal aim of this work. METHODS: The study was carried out on a group of 90 cardiotocograms recorded soon after a sample of pregnant women at term underwent labor induction by intracervical application of a gel containing 0.5 mg of PGE2 (dinoprostone). Special attention was paid to some characteristics of the cardiotocograms obtained during the first hour following administration of the gel: regularity of uterine contractions, total number of contractions, number of contractions having an intensity equal or superior to 50 mmHg, mean number of contractions during a period of 10 minutes, mean number of "effective" contractions during a period of 10 minutes, presence or absence of "excessive uterine activity" (tachysystole and/or hypersystole). RESULTS: Some cardiotocographic patterns were associated with a higher percentage of successful inductions, but the observed differences, not statistically significant, do not seem to be clinically interesting. CONCLUSIONS: However, it's not possible to exclude that a longer period of uterine contractions monitoring, perhaps lasting 2 hours instead of only 60 minutes, could lead to more useful information for the management choices