Associations of LP with BMI (continuous outcome) compared to LNP in a multivariate linear regression analysis.

1<p>Adjusted for age, sex, energy intake, milk intake.</p>2<p>Adjusted for model 1 plus milk avoidance, physical activity, educational status (36 missing because of incomplete data).</p

Population characteristics by LCT-13910 genotypes.

1<p><i>p</i> = 0.001 (LCT-13910 CC vs LCT-13910 CT/TT); Student <i>t</i>-test (36 missing because of incomplete data).</p

Estimated Odds Ratios and 95% Intervals for Obesity Relative to Normal Range weight and Overweight¹.

1<p>Adjusted for sex, age, energy intake, milk intake, milk avoidance, physical activity and educational status (36 missing because of incomplete data).</p

Flowchart of study participants.

<p>Abbreviations: MedDiet = Mediterranean diet; MetS =  Metabolic syndrome; WBC =  white blood cell.</p

Incidence of new cases of metabolic syndrome during the follow-up among subjects initially free of metabolic syndrome according to baseline sex-adjusted leukocyte counts.

<p>Odds ratios (95% confidence intervals).</p>a<p>P-value by χ² test.</p>b<p>P for trend.</p>c<p>Logistic regression model adjusted for intervention group, and baseline age, tobacco use, physical activity, Mediterranean diet score and alcohol consumption.</p>d<p>Logistic regression models adjusted for variables used in model 1 plus baseline BMI and recruitment centre.</p>e<p>Logistic regression models adjusted for variables used in model 2 plus baseline features of the metabolic syndrome.</p

Associations between changes in WBC counts that occurred during the follow-up and incidence of MetS.

<p>Odds ratios (95% confidence intervals).</p><p>Logistic regression models (outcome: MetS; independent variable: participants were dichotomized in two categories: a) those who remained in the same blood cell (leukocyte, neutrophil and lymphocyte) quartiles (2^nd, 3^rd, or 4^th) or switched to a higher quartile during the follow-up; and b) those who remained in the 1^st quartile or switched to a lower sex-adjusted quartile during the follow-up).</p>a<p>Adjusted for the intervention group, and baseline variables: age, current and former smoker, physical activity, Mediterranean diet score, alcohol BMI and recruitment node; ^b Model 1 plus adjusting for changes in body weight and Mediterranean diet score; ^c Model 2 plus adjusting for MetS components.</p

Incidence of each metabolic syndrome component among subjects initially free of its respective component according to baseline sex–adjusted leukocyte counts. Odds ratios (95% confidence intervals).

a<p>P-value =  χ² test; ^b P for trend; ^c Logistic regression models adjusted for intervention group, and baseline variables: age, current and former smoker, physical activity, Mediterranean diet score and alcohol; ^d Logistic regression model adjusted for model 1 plus baseline BMI and recruitment node.</p

Baseline characteristics of participants across sex-adjusted leukocyte count quartiles (first to fourth: Q1 to Q4).

a<p>ANOVA for continuous variables and χ² for categorical variables test were used for comparisons across the total leucocyte count quartiles.</p

Prevalence of metabolic syndrome for sex-adjusted quartiles of total white blood cell count and leukocyte subtypes.

<p>Odds ratios (95% confidence intervals) with the lowest quartile as the reference category.</p>a<p>Logistic regression models adjusted for intervention group, and baseline age, BMI, tobacco use, physical activity, Mediterranean diet score, alcohol consumption and study centre; NA: Not applicable.</p

Age of consumers included in the PlantLIBRA PFS Consumer Survey and of those reporting adverse effects.

<p>Age of consumers included in the PlantLIBRA PFS Consumer Survey and of those reporting adverse effects.</p