5,093 research outputs found

    What information-related activities do people with ESKD use?

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    Background Information practice is an emerging area of research that seeks to reveal how people learn to connect with the complex multimodal information landscapes that informs their ability to make decisions. Previous research has identified that people with end stage kidney disease (ESKD) tend to adopt a ‘received’ or ‘engaged’ view of information but little is known about the activities of information practice. Objectives This research project sought to identify the: i) information-related activities; and ii) how information is used. Methods Using a constructivist qualitative methodology, ten people with ESKD living in a large metropolitan city were purposively selected and interviewed. Data was subject to thematic analysis by researchers from nursing and information science. Saturation of themes was achieved. Results Participants were between 38 and 72 years, had been receiving kidney replacement therapy from 2 weeks to 31 years. Eight participants reported having access to the internet but none participated in chat rooms. The activities were conceptualized into themes as listening, seeking, searching, sharing and observing. These activities enabled people to create, reflect on and evaluate the information needed to inform their decision-making Conclusion/Application to Clinical Practice The information practice research approach will enable a better understanding of the underlying relationship between information, knowledge and experience to be better understood. For renal nurses who are involved in patient education being able to recognise the way people use information will assist in individualizing educational sessions and tailoring teaching strategies to make it more meaningful

    The Adversary Process in Child Custody Proceedings

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    Ultraviolet Spectra of Acetic Acid, Glycine, and Glyphosate

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    The influence of pH on the ultraviolet spectra of 0.001, 0.005, and 0.010 M glyphosate, glycine, and acetic acid was investigated. Each dilution of each acid was adjusted to acidic, neutral, and basic pH values. Ultraviolet spectra were recorded from 300 to 200 nm for each acid-dilution-pH combination. The wavelength of maximum absorption (Lambdamax) of glyphosate and glycine was slightly higher in the high pH solutions than in the neutral and low pH solutions. The Lambdamax of acetic acid was apparently unaffected by changes in ph. Molar extinction coefficients (epsilon) at Lambdamax increased with pH for all three acids. Regression analysis of the absorbance versus concentration for each acid-pH combination indicated linear relationships. Coefficients of determination (r2) were greater than 0.88 at both 210 and 215 nm for all acids and pH value

    A review of selected bee products as potential anti-bacterial, anti-fungal, and anti-viral agents

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    Antimicrobial resistance (AMR) is one of the greatest medical challenges the world faces. It was estimated recently that by 2050, AMR will account for 10 million extra deaths annually with additional economic costs in the region of $100 trillion. In order to combat this, novel antimicrobial agents with a broad spectrum of activity are required. Bee products, including; honey, propolis, defensins, royal jelly, bee pollen and venom have been used to treat infectious diseases for several centuries, although they were largely disregarded by Western medicine during the antibiotic era. There has since been a resurgence in interest in their antimicrobial properties, especially due to their reported activity against multi-drug resistant pathogens displaying high levels of AMR. In this paper we review the current scientific literature of honey, propolis, honey bee, defensins, royal jelly, bee pollen and bee venom. We highlight the antimicrobial activity each of these products has displayed and potential future research directions

    Quantization of Hyperbolic N-Sphere Scattering Systems in Three Dimensions

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    Most discussions of chaotic scattering systems are devoted to two-dimensional systems. It is of considerable interest to extend these studies to the, in general, more realistic case of three dimensions. In this context, it is conceptually important to investigate the quality of semiclassical methods as a function of the dimensionality. As a model system, we choose various three dimensional generalizations of the famous three disk problem which played a central role in the study of chaotic scattering in two dimensions. We present a quantum-mechanical treatment of the hyperbolic scattering of a point particle off a finite number of non-overlapping and non-touching hard spheres in three dimensions. We derive expressions for the scattering matrix S and its determinant. The determinant of S decomposes into two parts, the first one contains the product of the determinants of the individual one-sphere S-matrices and the second one is given by a ratio involving the determinants of a characteristic KKR-type matrix and its conjugate. We justify our approach by showing that all formal manipulations in these derivations are correct and that all the determinants involved which are of infinite dimension exist. Moreover, for all complex wave numbers, we conjecture a direct link between the quantum-mechanical and semiclassical descriptions: The semiclassical limit of the cumulant expansion of the KKR-type matrix is given by the Gutzwiller-Voros zeta function plus diffractional corrections in the curvature expansion. This connection is direct since it is not based on any kind of subtraction scheme involving bounded reference systems. We present numerically computed resonances and compare them with the corresponding data for the similar two-dimensional N-disk systems and with semiclassical calculations.Comment: 35 pages, LaTeX plus 8 Postscript figures, uses epsf.sty, epsfig.sty and epsf.te

    A versatile, high through-put, bead-based phagocytosis assay for Plasmodium falciparum

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    Abstract Antibody-mediated phagocytosis is an important immune effector mechanism against Plasmodium falciparum-infected erythrocytes (IE); however, current phagocytosis assays use IE collected from infected individuals or from in vitro cultures of P. falciparum, making them prone to high variation. A simple, high-throughput flow cytometric assay was developed that uses THP-1 cells and fluorescent beads covalently-coupled with the malarial antigen VAR2CSA. The assay is highly repeatable, provides both the overall percent phagocytosis and semi-quantitates the number of antigen-coupled beads internalized

    Door to Door Survey and Community Participation to Implement a New County Mosquito Control Program in Wayne County, North Carolina, USA

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    Community involvement in mosquito management programs provides more sustainable and effective organization and service. A door to door survey in Wayne County, NC carried out by student volunteers, resulted in 60 household responses. Residents had not previously experienced outreach from the county (88%), and 95% of them thought the student door to door survey was an effective form of outreach. One third of the residents thought mosquitoes were severe where they lived, but only 9% thought they had any containers in their yard that might breed mosquitoes. Only 15% of the residents were concerned about mosquito borne diseases. These responses provide evidence that outreach and education on mosquito control and diseases were necessary steps for future mosquito control community planning. Originally published in International Journal of Environmental Research and Public Health 2009 Vol. 6, No. 8

    NanoSIMS results from olivine-hosted melt embayments: Magma ascent rate during explosive basaltic eruptions

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    The explosivity of volcanic eruptions is governed in part by the rate at which magma ascends and degasses. Because the time scales of eruptive processes can be exceptionally fast relative to standard geochronometers, magma ascent rate remains difficult to quantify. Here we use as a chronometer concentration gradients of volatile species along open melt embayments within olivine crystals. Continuous degassing of the external melt during magma ascent results in diffusion of volatile species from embayment interiors to the bubble located at their outlets. The novel aspect of this study is the measurement of concentration gradients in five volatile elements (CO2, H2O, S, Cl, F) at fine-scale (5–10 μm) using the NanoSIMS. The wide range in diffusivity and solubility of these different volatiles provides multiple constraints on ascent timescales over a range of depths. We focus on four 100–200 μm, olivine-hosted embayments erupted on October 17, 1974 during the sub-Plinian eruption of Volcán de Fuego. H2O, CO2, and S all decrease toward the embayment outlet bubble, while F and Cl increase or remain roughly constant. Compared to an extensive melt inclusion suite from the same day of the eruption, the embayments have lost both H2O and CO2 throughout the entire length of the embayment. We fit the profiles with a 1-D numerical diffusion model that allows varying diffusivities and external melt concentrations as a function of pressure. Assuming a constant decompression rate from the magma storage region at approximately 220 MPa to the surface, H2O, CO2 and S profiles for all embayments can be fit with a relatively narrow range in decompression rates of 0.3–0.5 MPa/s, equivalent to 11–17 m/s ascent velocity and an 8 to 12 minute duration of magma ascent from ~ 10 km depth. A two stage decompression model takes advantage of the different depth ranges over which CO2 and H2O degas, and produces good fits given an initial stage of slow decompression (0.05–0.3 MPa/s) at high pressure (< 145 MPa), with similar decompression rates to the single-stage model for the shallower stage. The magma ascent rates reported here are among the first for explosive basaltic eruptions and demonstrate the potential of the embayment method for quantifying magmatic timescales associated with eruptions of different vigor
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