Fisiopatología de la pancreatitis crónica

Chronic Pancreatitis is characterized by progressive and irreversible damage of the pancreas, many etiologies are known but chronic alcohol ingestion is the primary cause. Recently there have been important advances in knowledge of the pathogenesis of alcohol damage. Important advances have also been made in regard to the mechanisms of pancreatic fibrinogenesis and the role of the stellate cells in the fibrosis of this disease. Genetic mutations involved in the process of activation/inactivation of trypsinogen in the pancreas, and other mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that affect bicarbonate secretion, have been described as related to the development of chronic Pancreatitis of different etiologies such as idiopathic, alcoholic and tropical Pancreatitis. © 2008 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología

Fisiopatología de la pancreatitis crónica

Chronic Pancreatitis is characterized by progressive and irreversible damage of the pancreas, many etiologies are known but chronic alcohol ingestion is the primary cause. Recently there have been important advances in knowledge of the pathogenesis of alcohol damage. Important advances have also been made in regard to the mechanisms of pancreatic fibrinogenesis and the role of the stellate cells in the fibrosis of this disease. Genetic mutations involved in the process of activation/inactivation of trypsinogen in the pancreas, and other mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) that affect bicarbonate secretion, have been described as related to the development of chronic Pancreatitis of different etiologies such as idiopathic, alcoholic and tropical Pancreatitis. © 2008 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología

Tuberculosis esofágica: Informe de un caso

We report the case of an immune-competent man with symptoms of upper gastrointestinal bleeding secondary to esophageal ulcers of tubercular origin. Gastrointestinal involvement from Mycobacterium tuberculosis is rare even in patients with numerous occurrences of pulmonary and extrapulmonary diseases. The most frequently affected sites are the terminal ileum and the peritoneum. Esophageal tuberculosis is exotic and is usually secondary to extension from neighboring infected organs such as the mediastinal nodes and/or the bronchi. Clinical, endoscopic and radiological pictures of the esophageal disease often mimic malignancy. Tuberculosis treatment is the mainstay of treatment, and surgery is rarely required. © 2014 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología

Tuberculosis esofágica: Informe de un caso

We report the case of an immune-competent man with symptoms of upper gastrointestinal bleeding secondary to esophageal ulcers of tubercular origin. Gastrointestinal involvement from Mycobacterium tuberculosis is rare even in patients with numerous occurrences of pulmonary and extrapulmonary diseases. The most frequently affected sites are the terminal ileum and the peritoneum. Esophageal tuberculosis is exotic and is usually secondary to extension from neighboring infected organs such as the mediastinal nodes and/or the bronchi. Clinical, endoscopic and radiological pictures of the esophageal disease often mimic malignancy. Tuberculosis treatment is the mainstay of treatment, and surgery is rarely required. © 2014 Asociaciones Colombianas de Gastroenterología, Endoscopia digestiva, Coloproctología y Hepatología