Demographic characteristics and key details of medical history among participants.

<p>Demographic characteristics and key details of medical history among participants.</p

Exposure assessment and classification of participants according to residential levels of atmospheric particulate matter.

<p>Patients were classified into 3 groups according to the ambient PM₁₀ class of their residence. Patients who resided in cities with Class 2 PM₁₀ pollution were classified in the <i>Low PM</i> group, while the <i>High PM</i> group included cases with Class 3 or higher PM₁₀ pollution. Patients living in areas with PM₁₀ concentrations that varied between Class 2 and Class 3 were classified as the <i>Medium PM g</i>roup.</p

Logistic regression modeling of factors associated with atmospheric particulate matter.

a<p><i>P</i> value was adjusted by cigarette-smoking status.</p>b<p>After excluding cases with history of gynecological disease or operation.</p>c<p>Patients without receipt of neoadjuvant chemotherapy were included in analyses.</p>d<p>Only invasive cases were included in analyses.</p

Study sample flow diagram.

<p>Study sample flow diagram.</p

Concentration limit for ambient air pollutants.

<p>Concentration limit for ambient air pollutants.</p

LAPTM4B genotype and clinicopathological variables.

<p>LAPTM4B, lysosome-associated protein transmembrane 4 beta; ER, estrogen receptor;</p><p>PR, progestogen receptor; Triple-negative, ER, PR and C-erbB2 negative.</p

The sequencing results of PCR products.

<p>(A). LAPTM4B*1; (B).LAPTM4B*2.</p

Genotype and expression of LAPTM4B protein in breast cancer tissues.

<p>(A) The genotype of LAPTM4B in representive breast cancer tissues. Lane 2, 4: *1/1 genotype; lane 3, 5: *1/2 genotypes; and lane 1: *2/2 genotype. (B) The mRNA levels of LAPTM4B in breast cancer tissues. The data represent one of three independent experiments.</p

LAPTM4B genotypes and breast cancer prognosis.

<p>(A) genotype *2 of LAPTM4B had shorter breast relapse-free survival (P = 0.012). (B) Genotype *2 of LAPTM4B was associated with shorter overall survival (P = 0.018).</p

Distribution of LAPTM4B alleles in cancer cases and controls.

<p>LAPTM4B, lysosome-associated protein transmembrane 4 beta; OR, odds ratio;</p><p>CI, confidence interval.</p