27 research outputs found

    The Grizzly, October 30, 1990

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    Ursinus Honored at Governor\u27s Mansion • Sam Stretton To Speak • Glassmoyer Retires • Heefner New Board President • The Gender of Speech: A Tri-Lambda Lecture • Career Day November 6th • Forbes to Speak to Clergy • Animal Lovers Unite • Mock DWI A Hit • Student Camp Experience • David is Great!! • Presenting Protheatre: The Changeling • Crutcher Leads Team• Muhlenberg Falls • Swimmers Open Season at Relay Meet • Women Running To MAC\u27s • Men Go for MAC Title • Soccer • Letters: Keep Ursinus Clean; Quad Keys Revoked?; Signs Stolen; Security, Please Hold • Environmentally Concerned? Get Active • Bush\u27s Environmental Lip Service • This Time for Real • Nature Versus Nurture: A Step in Solving the Puzzlehttps://digitalcommons.ursinus.edu/grizzlynews/1262/thumbnail.jp

    The sound of silence:Transgene silencing in mammalian cell engineering

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    To elucidate principles operating in native biological systems and to develop novel biotechnologies, synthetic biology aims to build and integrate synthetic gene circuits within native transcriptional networks. The utility of synthetic gene circuits for cell engineering relies on the ability to control the expression of all constituent transgene components. Transgene silencing, defined as the loss of expression over time, persists as an obstacle for engineering primary cells and stem cells with transgenic cargos. In this review, we highlight the challenge that transgene silencing poses to the robust engineering of mammalian cells, outline potential molecular mechanisms of silencing, and present approaches for preventing transgene silencing. We conclude with a perspective identifying future research directions for improving the performance of synthetic gene circuits.ISSN:2405-472

    Utilization of social media communities for caregiver information support in stroke recovery: An analysis of content and interactions

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    Background Caregivers often use the internet to access information related to stroke care to improve preparedness, thereby reducing uncertainty and enhancing the quality of care. Method Social media communities used by caregivers of people affected by stroke were identified using popular keywords searched for using Google. Communities were filtered based on their ability to provide support to caregivers. Data from the included communities were extracted and analysed to determine the content and level of interaction. Results There was a significant rise in the use of social media by caregivers of people affected by stroke. The most popular social media communities were charitable and governmental organizations with the highest user interaction–this was for topics related to stroke prevention, signs and symptoms, and caregiver self-care delivered through video-based resources. Conclusion Findings show the ability of social media to support stroke caregiver needs and practices that should be considered to increase their interaction and support

    Utilization of social media communities for caregiver information support in stroke recovery:an analysis of content and interactions

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    BACKGROUND: Caregivers often use the internet to access information related to stroke care to improve preparedness, thereby reducing uncertainty and enhancing the quality of care. METHOD: Social media communities used by caregivers of people affected by stroke were identified using popular keywords searched for using Google. Communities were filtered based on their ability to provide support to caregivers. Data from the included communities were extracted and analysed to determine the content and level of interaction. RESULTS: There was a significant rise in the use of social media by caregivers of people affected by stroke. The most popular social media communities were charitable and governmental organizations with the highest user interaction–this was for topics related to stroke prevention, signs and symptoms, and caregiver self-care delivered through video-based resources. CONCLUSION: Findings show the ability of social media to support stroke caregiver needs and practices that should be considered to increase their interaction and support
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