Transmit and Receive Array Structure Design of Two-Dimensional hybrid Phased-MIMO Radar based on Nested Array

In order to reduce the loss of Degree of Freedom (DOF) brought by the transmit subarray splitting of two-dimensional hybrid phased-MIMO radar, this paper presents a design method of transmitting and receiving array based on nested array structure. Firstly, a two-dimensional hybrid phased-MIMO radar transmitting array based on one-dimensional nested array is presented. On this basis, the receiving end is set as a nested array, and finally a virtual array and difference coarray are formed to expand the number of virtual array elements. The expansion increases the DOF of arrays while preserving the advantages of hybrid phased-MIMO radars. Simulation experiments show that compared with the traditional and coprime hybrid phased-MIMO radar, the proposed method can effectively improve the array DOF and Direction-of-Arrival (DOA) estimation accuracy

Transmit and Receive Array Structure Design of Two-Dimensional hybrid Phased-MIMO Radar based on Nested Array

In order to reduce the loss of Degree of Freedom (DOF) brought by the transmit subarray splitting of two-dimensional hybrid phased-MIMO radar, this paper presents a design method of transmitting and receiving array based on nested array structure. Firstly, a two-dimensional hybrid phased-MIMO radar transmitting array based on one-dimensional nested array is presented. On this basis, the receiving end is set as a nested array, and finally a virtual array and difference coarray are formed to expand the number of virtual array elements. The expansion increases the DOF of arrays while preserving the advantages of hybrid phased-MIMO radars. Simulation experiments show that compared with the traditional and coprime hybrid phased-MIMO radar, the proposed method can effectively improve the array DOF and Direction-of-Arrival (DOA) estimation accuracy

An optimizing nested MIMO array with hole-free difference coarray

According to the newly proposed nested MIMO (Multiple-Input Multiple-Input Multiple Output Multiple Array) array design method, we propose to replace the traditional nested array into an optimizing nested array, ie, to optimizing nested MIMO array design. It not only retains the original advantage of nested MIMO array design closed expression with array element position and degree of freedom(DOF), but also greatly improves the array aperture and DOF. Optimizing nested MIMO array firstly uses the optimizing nested array as the transmitting and receiving arrays, and then make the difference set processing for the coarray of MIMO array (coarray, CA). By properly designing the array spacing of the transmitting and receiving arrays, we can obtain a non-porous difference array. When the total number of array elements is given, by analyzing the characteristics of the array structure, the best array element number of the transmitting and receiving arrays can be obtained. Simulation experiments show that compared with the nested MIMO array design, the proposed method can effectively expand the array aperture, increase the DOF, and increase the DOA estimation accuracy of the MIMO radar without increasing the number of actual array elements

An optimizing nested MIMO array with hole-free difference coarray

According to the newly proposed nested MIMO (Multiple-Input Multiple-Input Multiple Output Multiple Array) array design method, we propose to replace the traditional nested array into an optimizing nested array, ie, to optimizing nested MIMO array design. It not only retains the original advantage of nested MIMO array design closed expression with array element position and degree of freedom(DOF), but also greatly improves the array aperture and DOF. Optimizing nested MIMO array firstly uses the optimizing nested array as the transmitting and receiving arrays, and then make the difference set processing for the coarray of MIMO array (coarray, CA). By properly designing the array spacing of the transmitting and receiving arrays, we can obtain a non-porous difference array. When the total number of array elements is given, by analyzing the characteristics of the array structure, the best array element number of the transmitting and receiving arrays can be obtained. Simulation experiments show that compared with the nested MIMO array design, the proposed method can effectively expand the array aperture, increase the DOF, and increase the DOA estimation accuracy of the MIMO radar without increasing the number of actual array elements

miR-3928v is induced by HBx via NF-κB/EGR1 and contributes to hepatocellular carcinoma malignancy by down-regulating VDAC3

Abstract Background Hepatitis B virus (HBV) plays a critical role in the tumorigenic behavior of human hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) have been reported to participate in HCC development via the regulation of their target genes. However, HBV-modulated miRNAs involved in tumorigenesis remain to be identified. Here, we found that a novel highly expressed miRNA, TLRC-m0008_3p (miR-3928v), may be an important factor that promotes the malignancy of HBV-related HCC. Methods Solexa sequencing was applied to profile miRNAs, and RT-qPCR was used to identify and quantitate miRNAs. We studied miR-3928v function in HCC cell lines by MTT, colony formation, migration/invasion, and vascular mimicry (VM) assays in vitro and by a xenograft tumor model in vivo. Finally, we predicted and verified the target gene of miR-3928v by a reporter assay, studied the function of this target gene, and cloned the promoter of miR-3928v and the transcription factor for use in dual-luciferase reporter assays and EMSAs. Results A variant of miR-3928 (miR-3928v) was identified and found to be highly expressed in HBV (+) HCC tissues. Voltage-dependent anion channel 3 (VDAC3) was validated as a target of miR-3928v and found to mediate the effects of miR-3928v in promoting HCC growth and migration/invasion. Furthermore, HBx protein increased early growth response 1 (EGR1) expression and facilitated its translocation into the nucleus to enhance miR-3928v promoter activity in an NF-κB signaling-dependent manner. Conclusions miR-3928v is induced by HBx through the NF-κB/EGR1 signaling pathway and down-regulates the tumor suppressor gene VDAC3 to accelerate the progression of HCC

Retraction Note: miR-3928v is induced by HBx via NF-κB/ EGR1 and contributes to hepatocellular carcinoma malignancy by down-regulating VDAC3

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s13046-018-0681-y

Le Cri du peuple : journal politique quotidien

18 décembre 18881888/12/18 (A6,N1881)-1888/12/18