Salinity stress induces the production of 2-(2-phenylethyl)chromones and regulates novel classes of responsive genes involved in signal transduction in Aquilaria sinensis calli

Gene ontology (GO) functional enrichment analysis of assembled unigenes. A total of 53514 matched unigenes were classfied into three principal categories: biological process, cellular component and molecular function. (PPTX 165 kb

Impact of Thrombocytopenia on In-Hospital Outcome in Patients Undergoing Percutaneous Coronary Intervention

Background. Thrombocytopenia was intuitively considered to be associated with higher risk of bleeding and multiple comorbidities after percutaneous coronary intervention (PCI). However, controversial results exist, and the real-world clinical impact of thrombocytopenia in patients undergoing PCI is largely unknown. The aim of this study was to evaluate the influence of baseline thrombocytopenia on the prognosis of patients undergoing PCI. Methods. Using the West China Hospital Inpatient Sample database, patients who underwent PCI were identified from August 2012 to January 2019. Baseline thrombocytopenia was defined as a preprocedural platelet count of or less obtained from a routine blood sample taken within 48 hours before coronary PCI. The clinical effect of the advanced thrombocytopenia group (), according to the median value of platelet count in the thrombocytopenia cohort, was further assessed. The primary outcome was a composite of in-hospital death, bleeding events, and post-PCI transfusion. Results. Of 9531 patients enrolled in our study, 936 had baseline thrombocytopenia and 8595 patients did not have. There were no significant differences in the primary outcome between the two groups. However, advanced thrombocytopenia was independently associated with higher risk of primary outcome (OR 1.67, 95% CI 1.06 to 2.65, ). Acute coronary syndrome (ACS) patients with thrombocytopenia were associated with higher odds of major bleeding () (OR 2.56, 95% CI 1.24 to 5.44, ). Compared with the nonthrombocytopenia group, the thrombocytopenia group with ticagrelor use had higher odds of major bleeding (OR 9.7, 95% CI 1.57 to 60.4 versus OR 0.22, 95% CI 0.03 to 1.69, interaction ). Conclusions. It seems feasible for patients with thrombocytopenia to receive PCI, but close attention should be paid to advanced thrombocytopenia, the risk of postprocedure bleeding in ACS patients, and the use of more potent P2Y12 inhibitor

The Impact of Variational Primary Collaterals on Cerebral Autoregulation

The influence of the anterior and posterior communicating artery (ACoA and PCoA) on dynamic cerebral autoregulation (dCA) is largely unknown. In this study, we aimed to test whether substantial differences in collateral anatomy were associated with differences in dCA in two common types of stenosis according to digital subtraction angiography (DSA): either isolated basal artery and/or bilateral vertebral arteries severe stenosis/occlusion (group 1; group 1A: with bilateral PCoAs; and group 1B: without bilateral PCoAs), or isolated unilateral internal carotid artery severe stenosis/occlusion (group 2; group 2A: without ACoA and with PCoA; group 2B: with ACoA and without PCoAs; and group 2C: without both ACoA and PCoA). The dCA was calculated by transfer function analysis (a mathematical model), and was evaluated in middle cerebral artery (MCA) and/or posterior cerebral artery (PCA). Of a total of 231 non-acute phase ischemic stroke patients who received both dCA assessment and DSA in our lab between 2014 and 2017, 51 patients met inclusion criteria based on the presence or absence of ACoA or PCoA, including 21 patients in the group 1, and 30 patients in the group 2. There were no significant differences in gender, age, and mean blood pressure between group 1A and group 1B, and among group 2A, group 2B, and group 2C. In group 1, the PCA phase difference values (autoregulatory parameter) were significantly higher in the subgroup with patent PCoAs, compared to those without. In group 2, the MCA phase difference values were higher in the subgroup with patent ACoA, compared to those without. This pilot study found that the cross-flow of the ACoA/PCoA to the affected area compensates for compromised dCA in the affected area, which suggests an important role of the ACoA/PCoA in stabilizing cerebral blood flow

Automated Building of Sentence-Level Parallel Corpus and Chinese-Hungarian Dictionary

Decades of work have been conducted on automated building of parallel corpus and automatic dictionary in the field of natural language processing. However, rarely have any studies been done between high-density character-based languages and medium-density word-based languages due to the lack of resources and fundamental linguistic differences. In this paper, we describe a methodology for creating a sentence-level paralleled corpus and an automatic bilingual dictionary between Chinese (a high-density character-based language) and Hungarian (a medium-density word-based language). This method will possibly be applied to create Chinese-Hungarian bilingual dictionary for the Sztaki Dictionary project [http://szotar.sztaki.hu/]

Sequences of Frustration and Confusion, and Learning

We use sensor-free affect detection and a discovery with models approach to explore the relationship between affect over varying durations and learning outcomes among students using Cognitive Tutor Algebra. Researchers have suggested that the affective state of confusion can have positive effects on learning as long as students can resolve the confusion, and recent research seems to accord with this hypothesis. However, there is room for concern that some of this earlier work may have conflated frustration and confusion. We replicate these analyses using sensor-free automated detectors trained to distinguish the two affective states. Our analyses suggest that the effect may be stronger for frustration than confusion, but is strongest when these two affective states are taken together

Design and implementation of a heterogeneous distributed database system

This paper introduces a heterogeneous distributed database system called LSZ system, where LSZ is an abbreviation of Li Shizhen, an ancient Chinese medical scientist. LSZ system adopts cluster as distributed database node (or site). Each cluster consists of one or several microcomputers and one server. The paper describes its basic architecture and the prototype implementation, which includes query processing and optimization, transaction manager and data language translation. The system provides a uniform retrieve and update user interface through global relational data language GRDL