Evolution of pore structure, submaceral composition and produced gases of two Chinese coals during thermal treatment

This research was funded by the Research Program for Excellent Doctoral Dissertation Supervisor of Beijing (grant no. YB20101141501), the Fundamental Research Funds for Central Universities (grant no. 35832015136) and Key Project of Coal-based Science and Technology in Shanxi Province-CBM accumulation model and reservoir evaluation in Shanxi province (grant no. MQ2014-01).Peer reviewedPostprin

Poly[bis­[chlorido­cop­per(I)]-μ4-1,4-bis­[1-(3-pyridylmeth­yl)-1H-benzimid­azol-2-yl]butane]

The title CuI coordination polymer, [Cu2Cl2(C30H28N6)]n, was obtained by reaction of CuCl2·2H2O and 1,4-bis­[1-(3-pyridyl­meth­yl)-1H-benzimidazol-2-yl]butane. Each CuI cation is three-coordinated by a ClN2 donor set. The anion acts as a tetra­dentate ligand, linking CuI centres into a polymeric chain

Flexibility is a mechanical determinant of antimicrobial activity for amphipathic cationic α-helical antimicrobial peptides

AbstractAntimicrobial peptides (AMPs) are recognized as the potential substitutions for common antibiotics. Flexibility has been demonstrated to be a dominant on antimicrobial activity of an AMP, similar to the structural parameters such as hydrophobicity and hydrophobic moment as well as positive charge. To better understand the effect of flexibility on antimicrobial activity, we herein examined seventy-eight peptides derived from nine different species. Defined as a weighted average of amino acid flexibility indices over whole residue chain of AMP, flexibility index was used to scale the peptide flexibility and indicated to be a reflection of mechanical properties such as tensile and flexural rigidities. The results demonstrated that flexibility index is relevant to but different from other structural properties, may enhance activity against Escherichia coli for stiff clustered peptides or reduce activity against E. coli for flexible clustered peptides, and its optimum occurs at about −0.5. This effect of flexibility on antimicrobial activity may be involved to the antimicrobial actions, such as stable peptide-bound leaflet formation and sequent stress concentration in target cell membrane, mechanically. The present results provide a new insight in understanding antimicrobial actions and may be useful in seeking for a new structure–activity relationship for cationic and amphipathic α-helical peptides

EFFECTS OF THE EXTERNAL MUSCLE SYSTEM ON THE FUNCTION OF HAMSTRINGS

The purpose of this study was to develop a device which can simulate the function of the hamstrings and increase these muscles' strength. By wearing it during daily training, one can train the hamstrings according to the specific needs of each sport event. Fifteen subjects were involved in the study and the external muscle system was examined by using EMG and kinetics methods. The results showed that there was an increasing trend in jumping performance and muscle co-contraction (

IS THE HIGH-TOP SHOE MORE PROTECTIVE IN LANDING ON A TILTED SURFACE: A KINEMATIC AND ELECTROMYOGRAPHIC EVALUATION

The purpose of this study was to explore the effect of high-top and low-top shoes on ankle inversion kinematics and pre-landing EMG activation of ankle evertor muscles during the landing on a combined inverted and plantarflexed surface. Thirteen male subjects were instructed to wear high-top & low-top shoes to execute self-initiated drop landings in each of the 8 landing conditions, i.e. 2 shoes × 4 surface conditions, on an inverted (or combined plantarflexed) platform. Ankle inversion kinematics and the EMG from the tibialis anterior, peroneal longus, and peroneus brevis muscles were collected simultaneously. The results indicated that shoe collar heights did not influence the ankle inversion kinematics during landing. However, wearing high-top shoes resulted in a significant posterior onset time of the tibialis anterior and peroneus brevis muscles, and lowered the pre-landing EMG activation of ankle evertor muscles prior to foot contact during landing on the inverted surface

6-Meth­oxy-2-methyl-1-m-tolyl-1H-benzimidazole hemihydrate

The title compound, C16H16N2O·0.5H2O, is a substituted 1-phenyl­benzimidazole, which belongs to the class of ATP-site inhibitors of the platelet-derived growth-factor receptor. In the crystal, the components are linked by an O—H⋯N hydrogen bond