The New Initiatives for Strengthening Public Human Resource Management

In this paper, we will analyze how to strengthen the public human resource management through knowledge management. Try to find out the reality of our public human resource management and the special reasons for this situation, the further to get the new methods and new measures for strengthening it

Activity map of a cortico-cerebellar loop underlying motor planning

The neocortex and cerebellum interact to mediate cognitive functions. It remains unknown how the two structures organize into functional networks to mediate specific behaviors. Here we delineate activity supporting motor planning in relation to the mesoscale cortico-cerebellar connectome. In mice planning directional licking based on short-term memory, preparatory activity instructing future movement depends on the anterior lateral motor cortex (ALM) and the cerebellum. Transneuronal tracing revealed divergent and largely open-loop connectivity between the ALM and distributed regions of the cerebellum. A cerebellum-wide survey of neuronal activity revealed enriched preparatory activity in hotspot regions with conjunctive input–output connectivity to the ALM. Perturbation experiments show that the conjunction regions were required for maintaining preparatory activity and correct subsequent movement. Other cerebellar regions contributed little to motor planning despite input or output connectivity to the ALM. These results identify a functional cortico-cerebellar loop and suggest the cerebellar cortex selectively establishes reciprocal cortico-cerebellar communications to orchestrate motor planning.</p

Tibetan Word Segmentation as Syllable Tagging Using Conditional Random Field

In this paper, we proposed a novel approach for Tibetan word segmentation using the conditional random field. We reformulate the segmentation as a syllable tagging problem. The approach labels each syllable with a word-internal position tag, and combines syllable(s) into words according to their tags. As there is no public available Tibetan word segmentation corpus, the training corpus is generated by another segmenter which has an F-score of 96.94% on the test set. Two feature template sets namely TMPT-6 and TMPT-10 are used and compared, and the result shows that the former is better. Experiments also show that larger training set improves the performance significantly. Trained on a set of 131,903 sentences, the segmenter achieves an F-score of 95.12% on the test set of 1,000 sentences. &copy; 2011 by Huidan Liu, Minghua Nuo, Longlong Ma, Jian Wu, and Yeping He.In this paper, we proposed a novel approach for Tibetan word segmentation using the conditional random field. We reformulate the segmentation as a syllable tagging problem. The approach labels each syllable with a word-internal position tag, and combines syllable(s) into words according to their tags. As there is no public available Tibetan word segmentation corpus, the training corpus is generated by another segmenter which has an F-score of 96.94% on the test set. Two feature template sets namely TMPT-6 and TMPT-10 are used and compared, and the result shows that the former is better. Experiments also show that larger training set improves the performance significantly. Trained on a set of 131,903 sentences, the segmenter achieves an F-score of 95.12% on the test set of 1,000 sentences. &copy; 2011 by Huidan Liu, Minghua Nuo, Longlong Ma, Jian Wu, and Yeping He

国产氯吡格雷与阿司匹林治疗稳定型冠心病的前瞻性临床随机对照试验

Objective: To compare the clinical efficacy of clopidogrel and aspirin therapy with stable coronary heart disease, to provide reliable clinical evidence in patients with stable coronary artery disease and to improve their life quality.Methods: 120 patients with stable coronary artery disease were randomly assigned to clopidogrel and aspirin group, of 60 patients were given blood pressure, lipid, blood sugar control conventional drug therapy and anti-myocardial ischemia. On this basis, the two groups were given clopidogrel and aspirin therapy. Compare the records of all patients before and after treatment platelet aggregation rate (PAR) between the treatment groups and; disease progression (death, deterioration of unstable angina, myocardial infarction), angina and ECG assessment of clinical efficacy. Heart and kidney function, the number of neutropenia, incidence of bleeding (gastrointestinal, mucosal bleeding) and other adverse reactions of patients receiving the treatment were also compared between the two groups.Results: After treatment, both groups of patients with PAR 28d were significantly lower, statistically significant changes (P&lt;0.05), PAR patients in the clopidogrel group was significantly lower than in the aspirin group (P&lt;0.05); within 28d clopidogrel myocardial infarction incidence rate of 1.6% in the control group the incidence by 10% in the clopidogrel group total efficiency 95% in the aspirin group efficiency 83.3%, the total effective rate between the two groups were significantly different (P&lt;0.05), clinical efficacy of clopidogrel Gray group is higher than that of aspirin group; ECG intwo groups of patients was statistically significant (P&lt;0.05), the improvement is more obvious in clopidogrel group. Conclusion: The efficacy of clopidogrel is superior to aspirin with stable coronary artery disease, as safe as aspirin, and worthy of promotion. promotion. 目的  通过比较氯吡格雷与阿司匹林治疗稳定型冠心病的临床疗效，为该病患者提供可靠的临床治疗依据。方法  将120例稳定型冠心病患者随机分为氯吡格雷组和阿司匹林组，每组60例，并且均给予降压、调脂、控制血糖及抗心肌缺血等常规药物治疗。在此基础上两组分别给以氯吡格雷和阿司匹林进行治疗。记录并评定所有患者治疗前后组内及治疗后组间血小板聚集率（PAR），病情恶化（死亡、恶化为不稳定型心绞痛、心肌梗死），心绞痛及心电图等临床指标。同时比较两组患者治疗后心肝肾功能、粒细胞数量减少、出血（消化道、粘膜出血）等不良反应的发生情况。结果  治疗28d后两组患者的PAR均显著降低，变化有统计学差异（P＜0.05），氯吡格雷组患者PAR显著低于阿司匹林组（P＜0.05）；28d内氯吡格雷组心梗发生率为1.6%，对照组发生率10%，氯吡格雷组总有效率95%，阿司匹林组总有效率83.3%，两组间总有效率比较有统计学差异（P＜0.05），氯吡格雷组临床疗效优于阿司匹林组；两组患者心电图疗效有统计学意义（P＜0.05），治疗后均有改善，氯吡格雷组更优。结论  氯吡格雷治疗稳定型冠心病的疗效优于阿司匹林，安全性相似，值得临床推广