1,045 research outputs found
Structural and functional characteristics of the promoter regions of the genes on human chromosome 22
The base composition pattern in the putative promoter region (PPRs) up to 5 Kb lengths of 682 human genes on Chromosome 22 (Chr22) was examined. Two-dimensional (2-D) and three-dimensional (2-D) functions were designed to delineate the DNA base composition, with four major patterns identified. It is found that 17.6% genes include TATA box, 28.0% GC box, 18.9% CAAT box and 38.4% CpG islands, and approximately 10 % genes have one of four putative initiator motifs. The occurrence of the promoter elements is tightly associated with the base composition features in the promoter regions, and the associations of the base composition features with occurrence of the promoter elements in the promoter regions mediate tissue-wide expression of the genes in human. The occurrence of two or more promoter elements in the promoter regions is required for the medium- and wide-range expression profiles of the human genes on Chr22. Thus, the reported data shed light on the characteristics of the PPRs of the human genes on Chr22, which may improve our understanding of regulatory roles of the PPRs with occurrence of the promoter elements in gene expression
Investigating the topological structure of quenched lattice QCD with overlap fermions by using multi-probing approximation
The topological charge density and topological susceptibility are determined
by multi-probing approximation using overlap fermions in quenched SU(3) gauge
theory. Then we investigate the topological structure of the quenched QCD
vacuum, and compare it with results from the all-scale topological density, the
results are consistent. Random permuted topological charge density is used to
check whether these structures represent underlying ordered properties.
Pseudoscalar glueball mass is extracted from the two-point correlation function
of the topological charge density. We study ensembles of different lattice
spacing with the same lattice volume , the results are
compatible with the results of all-scale topological charge density, and the
topological structures revealed by multi-probing are much closer to all-scale
topological charge density than that by eigenmode expansion.Comment: 12 pages,34 figure
Giant Magneto-Optical Sch\"{a}fer-Hubert Effect in Two-Dimensional van der Waals Antiferromagnets \textit{M}PS (\textit{M}=Mn, Fe, Ni)
The recent discovery of long-range magnetic order in atomically thin films
has triggered particular interest in two-dimensional (2D) van der Waals (vdW)
magnetic materials. In this paper, we perform a systematic theoretical study of
the magneto-optical Sch\"{a}fer-Hubert effect (MOSHE) in 2D vdW
antiferromagnetic \textit{M}PS (\textit{M} = Mn, Fe, Ni) with multifold
intralayer and interlayer magnetic orders. The formula for evaluating the MOSHE
in 2D magnets is derived by considering the influence of a non-magnetic
substrate. The MOSHE of monolayer and bilayer \textit{M}PS are considerably
large (), originating from the strong anisotropy of in-plane
optical conductivity. The Sch\"{a}fer-Hubert rotation angles are surprisingly
insensitive to the orientations of the N\'{e}el vector, while the
Sch\"{a}fer-Hubert ellipticities are identified to be a good criterion to
distinguish different interlayer magnetic orders. Our work establishes a
theoretical framework for exploring novel 2D vdW magnets and facilitates the
promising applications of the 2D \textit{M}PS family in antiferromagnetic
nanophotonic devices
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