8 research outputs found

    Zaburzenia rytmu i funkcji uk艂adu autonomicznego w przebiegu ostrych i przewlek艂ych chor贸b z zaj臋ciem prawej komory serca

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    The right and left hearts differ from one another in their anatomy and function. This disparity demonstrates itself in different heart muscle compositions, arrangements of cardiac conduction system elements, and distributions of autonomic nervous system receptors. These differences mean that diseases that mainly affect the right heart, such as acute pulmonary embolism, chronic pulmonary hypertension, right ventricular infarction or arrhythmogenic right ventricular cardiomyopathy, as well as some congenital heart diseases and connective tissue diseases, have a distinct clinical course and potential complications. This leads to an increased incidence of cardiac rhythm disturbances in this group, with some types of arrhythmia for every disease. In order to help clinicians select the best diagnostic and therapeutic methods, we here summarise current knowledge about arrhythmic complications and cardiac autonomic nervous system functions in diseases with right heart involvement.Prawa i lewa komora r贸偶ni膮 si臋 w swojej anatomii i funkcji, co ma sw贸j wyraz w odmiennej budowie miokardium, zawarto艣ci element贸w uk艂adu bod藕coprzewodz膮cego oraz dystrybucji receptor贸w autonomicznego uk艂adu nerwowego. Wymienione r贸偶nice sprawiaj膮, 偶e choroby przebiegaj膮ce g艂贸wnie z zaj臋ciem prawych jam serca, takie jak: ostra zatorowo艣膰 p艂ucna, przewlek艂e nadci艣nienie p艂ucne, zawa艂 prawej komory serca czy arytmogenna kardiomiopatia prawokomorowa, a tak偶e wybrane wrodzone wady serca czy niekt贸re choroby uk艂adowe tkanki 艂膮cznej, odr贸偶niaj膮 si臋 na tle innych schorze艅 swoj膮 patofizjologi膮, przebiegiem klinicznym oraz potencjalnymi komplikacjami. Prowadzi to r贸wnie偶 do zwi臋kszonej cz臋sto艣ci wywo艂ywania zaburze艅 rytmu serca, przy czym dla poszczeg贸lnych jednostek charakterystyczne s膮 inne rodzaje arytmii. W celu u艂atwienia klinicystom wyboru metod diagnostycznych i leczniczych w poni偶szym opracowaniu zebrano aktualn膮 wiedz臋 na temat zaburze艅 rytmu oraz funkcji autonomicznego uk艂adu nerwowego serca w schorzeniach przebiegaj膮cych z zaj臋ciem prawej komory

    Zastosowanie elektrokardiografii w ostrych i przewlek艂ych chorobach z zaj臋ciem prawej komory serca

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    Electrocardiography is a basic diagnostic tool and one that plays a significant role in differentiating many diseases,聽including those involving the right heart. The diagnosis of right ventricular (RV) pathology is difficult due to the complex聽structure and the wide spectrum of haemodynamic disorders resulting from its dysfunction. The use of a standard聽electrocardiogram (ECG) with right-sided leads can be a valuable complement of imaging tests, especially when these聽are not quickly available. Numerous electrocardiographic abnormalities are observed in the course of acute pulmonary聽embolism, chronic pulmonary hypertension, right ventricular myocardial infarction, or arrhythmogenic right ventricular聽cardiomyopathy, and some of these also have prognostic significance. Unfortunately, despite its simplicity and utility,聽ECG is insufficiently sensitive and specific to be the single tool in the recognition of RV pathologies. ECG is a common,聽inexpensive, non-invasive and easily accomplished complementary test, which can be useful in diagnostic algorithm of聽right heart diseases.Elektrokardiografia (EKG) odgrywa znacz膮c膮 rol臋 w r贸偶nicowaniu wielu chor贸b, w tym przebiegaj膮cych z zaj臋ciem prawego serca. Rozpoznanie patologii prawej komory (RV) bywa trudne ze wzgl臋du na z艂o偶on膮 budow臋 oraz szerokie spektrum zaburze艅 hemodynamicznych wynikaj膮cych z jej dysfunkcji. Standardowy zapis EKG czynno艣ci serca uzupe艂niony o rejestracj臋 odprowadze艅 prawokomorowych mo偶e by膰 w tym przypadku cennym uzupe艂nieniem bada艅 obrazowych, zw艂aszcza gdy te nie s膮 szybko dost臋pne. W przebiegu ostrej zatorowo艣ci p艂ucnej, nadci艣nienia p艂ucnego, zawa艂u prawej komory czy arytmogennej kardiomopatii prawokomorowej obserwuje si臋 liczne nieprawid艂owo艣ci elektrokardiograficzne pomocne w diagnostyce, a cz臋艣膰 z nich ma znaczenie prognostyczne. Niestety, mimo swojej prostoty i u偶yteczno艣ci EKG cechuje si臋 niedostateczn膮 czu艂o艣ci膮 i swoisto艣ci膮, by m贸g艂 stanowi膰 pojedyncze narz臋dzie diagnostyczne w wykrywaniu nieprawid艂owo艣ci RV. Elektrokardiografia to powszechne, tanie, nieinwazyjne i 艂atwe do wykonania badanie uzupe艂niaj膮ce, kt贸re mo偶e mie膰 istotne znaczenie w algorytmie diagnostycznym r贸偶nych chor贸b przebiegaj膮cych z zaj臋ciem RV

    Zaburzenia rytmu i funkcji uk艂adu autonomicznego w przebiegu ostrych i przewlek艂ych chor贸b z zaj臋ciem prawej komory serca

    Get PDF
    The right and left hearts differ from one another in their anatomy and function. This disparity demonstrates itself in different heart muscle compositions, arrangements of cardiac conduction system elements, and distributions of autonomic nervous system receptors. These differences mean that diseases that mainly affect the right heart, such as acute pulmonary embolism, chronic pulmonary hypertension, right ventricular infarction or arrhythmogenic right ventricular cardiomyopathy, as well as some congenital heart diseases and connective tissue diseases, have a distinct clinical course and potential complications. This leads to an increased incidence of cardiac rhythm disturbances in this group, with some types of arrhythmia for every disease. In order to help clinicians select the best diagnostic and therapeutic methods, we here summarise current knowledge about arrhythmic complications and cardiac autonomic nervous system functions in diseases with right heart involvement.Prawa i lewa komora r贸偶ni膮 si臋 w swojej anatomii i funkcji, co ma sw贸j wyraz w odmiennej budowie miokardium, zawarto艣ci element贸w uk艂adu bod藕coprzewodz膮cego oraz dystrybucji receptor贸w autonomicznego uk艂adu nerwowego. Wymienione r贸偶nice sprawiaj膮, 偶e choroby przebiegaj膮ce g艂贸wnie z zaj臋ciem prawych jam serca, takie jak: ostra zatorowo艣膰 p艂ucna, przewlek艂e nadci艣nienie p艂ucne, zawa艂 prawej komory serca czy arytmogenna kardiomiopatia prawokomorowa, a tak偶e wybrane wrodzone wady serca czy niekt贸re choroby uk艂adowe tkanki 艂膮cznej, odr贸偶niaj膮 si臋 na tle innych schorze艅 swoj膮 patofizjologi膮, przebiegiem klinicznym oraz potencjalnymi komplikacjami. Prowadzi to r贸wnie偶 do zwi臋kszonej cz臋sto艣ci wywo艂ywania zaburze艅 rytmu serca, przy czym dla poszczeg贸lnych jednostek charakterystyczne s膮 inne rodzaje arytmii. W celu u艂atwienia klinicystom wyboru metod diagnostycznych i leczniczych w poni偶szym opracowaniu zebrano aktualn膮 wiedz臋 na temat zaburze艅 rytmu oraz funkcji autonomicznego uk艂adu nerwowego serca w schorzeniach przebiegaj膮cych z zaj臋ciem prawej komory

    Zastosowanie elektrokardiografii w ostrych i przewlek艂ych chorobach z zaj臋ciem prawej komory serca

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    Electrocardiography is a basic diagnostic tool and one that plays a significant role in differentiating many diseases,聽including those involving the right heart. The diagnosis of right ventricular (RV) pathology is difficult due to the complex聽structure and the wide spectrum of haemodynamic disorders resulting from its dysfunction. The use of a standard聽electrocardiogram (ECG) with right-sided leads can be a valuable complement of imaging tests, especially when these聽are not quickly available. Numerous electrocardiographic abnormalities are observed in the course of acute pulmonary聽embolism, chronic pulmonary hypertension, right ventricular myocardial infarction, or arrhythmogenic right ventricular聽cardiomyopathy, and some of these also have prognostic significance. Unfortunately, despite its simplicity and utility,聽ECG is insufficiently sensitive and specific to be the single tool in the recognition of RV pathologies. ECG is a common,聽inexpensive, non-invasive and easily accomplished complementary test, which can be useful in diagnostic algorithm of聽right heart diseases.Elektrokardiografia (EKG) odgrywa znacz膮c膮 rol臋 w r贸偶nicowaniu wielu chor贸b, w tym przebiegaj膮cych z zaj臋ciem prawego serca. Rozpoznanie patologii prawej komory (RV) bywa trudne ze wzgl臋du na z艂o偶on膮 budow臋 oraz szerokie spektrum zaburze艅 hemodynamicznych wynikaj膮cych z jej dysfunkcji. Standardowy zapis EKG czynno艣ci serca uzupe艂niony o rejestracj臋 odprowadze艅 prawokomorowych mo偶e by膰 w tym przypadku cennym uzupe艂nieniem bada艅 obrazowych, zw艂aszcza gdy te nie s膮 szybko dost臋pne. W przebiegu ostrej zatorowo艣ci p艂ucnej, nadci艣nienia p艂ucnego, zawa艂u prawej komory czy arytmogennej kardiomopatii prawokomorowej obserwuje si臋 liczne nieprawid艂owo艣ci elektrokardiograficzne pomocne w diagnostyce, a cz臋艣膰 z nich ma znaczenie prognostyczne. Niestety, mimo swojej prostoty i u偶yteczno艣ci EKG cechuje si臋 niedostateczn膮 czu艂o艣ci膮 i swoisto艣ci膮, by m贸g艂 stanowi膰 pojedyncze narz臋dzie diagnostyczne w wykrywaniu nieprawid艂owo艣ci RV. Elektrokardiografia to powszechne, tanie, nieinwazyjne i 艂atwe do wykonania badanie uzupe艂niaj膮ce, kt贸re mo偶e mie膰 istotne znaczenie w algorytmie diagnostycznym r贸偶nych chor贸b przebiegaj膮cych z zaj臋ciem RV

    Periprocedural decrease in tumor necrosis factor alpha is a risk factor for atrial fibrillation recurrence after ablation

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    Background: Concentration of tumor necrosis factor alpha (TNF-alpha) might be useful in selecting patients with paroxysmal atrial fibrillation (PAF) who will benefit the most from pulmonary vein isolation. Material and methods: This is a prospective cohort study among patients with PAF who had sinus rhythm prior to undergoing either radiofrequency ablation or cryoablation procedure. Blood samples were collected at the start of the procedure and 16-24 h after. TNF-alpha concentrations were measured. Follow-up data was obtained during a structured telephone interview and 24-hour ECG Holter monitoring 12 months after the ablation procedure. Results: Thirty seven patients were enrolled. After 12-month follow-up 27 patients maintained sinus rhythm, 8 had recurrence of AF and 2 were lost to follow-up. There was no significant correlation between TNF-alpha concentrations in any of the samples and the recurrence of arrhythmia (for pre-procedural samples: 1.75 pg/ ml vs. 1.74 pg/ml; p = 0.72; for post-procedural samples: 1.49 pg/ml vs. 1.79 pg/ml; p = 0.16). In patients who had a recurrence of AF, we observed a decrease in the periprocedural TNF-alpha concentration (-0.12 pg/ml vs 0.05 pg/ml; p = 0.05). Conclusions: Neither pre- nor post-procedural TNF-alpha concentrations are predictive of ablation outcome in patients with PAF. We observed a decrease in the periprocedural TNF-alpha concentration in patients who had AF recurrence

    Periprocedural decrease in tumor necrosis factor alpha is a risk factor for atrial fibrillation recurrence after ablation

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    Background Concentration of tumor necrosis factor alpha (TNF-alpha) might be useful in selecting patients with paroxysmal atrial fibrillation (PAF) who will benefit the most from pulmonary vein isolation. Material and methods We performed prospective cohort study among patients with PAF who had sinus rhythm prior to undergoing either radiofrequency ablation or cryoablation procedure. Blood samples were collected at the start of the procedure and 16-24 h after. TNF-alpha concentrations were measured. Follow-up data was obtained during a structured telephone interview and 24-hour ECG Holter monitoring 12 months after the ablation procedure. Results Thirty seven patients were enrolled. After 12-month follow-up 27 patients maintained sinus rhythm, 8 had recurrence of AF and 2 were lost to follow-up. There was no significant correlation between TNF-alpha concentrations in any of the samples and the recurrence of arrhythmia (for pre-procedural samples: 1.75 pg/ml vs 1.74 pg/ml; p=0.72; for post-procedural samples: 1.49 pg/ml vs 1.79 pg/ml; p=0.16). In patients who had a recurrence of AF, we observed a decrease in the periprocedural TNF-alpha concentration (-0.12 pg/ml vs 0.05 pg/ml; p=0.05). Conclusions Neither pre- nor post-procedural TNF-alpha concentrations are predictive of ablation outcome in patients with PAF. We observed a decrease in the periprocedural TNF-alpha concentration in patients who had AF recurrence
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