The Dilemma and Practice Paths of Multi-entity Participation in the Rural Living Environment—A Case Study of District Y in Chongqing

The remediation of the rural living environment is not only an important aspect of comprehensively promoting rural revitalization but also directly influences the villagers’ sense of happiness and attainment. This paper, taking District Y in Chongqing as an example, explores the practice paths of multi-entity coordinated governance in the rural living environment. The paper affirms the leading role of the government, participation responsibilities of the market, social organizations, and villagers, thereby constructing a multi-entity coordinated governance mechanism to effectively address the prominent problems currently faced

Constraint Mechanism of Environmental Regulation on Carbon Emission of Heavy Industry in Chengdu-Chongqing Region of China

Regional differences and development heterogeneity lead to an unbalanced distribution of heavy industry in Chengdu-Chongqing region of China. Under the background of low-carbon development, clarifying the constraint mechanism of environmental regulations on carbon emissions of heavy industry becomes more important to solve prominent problems of resources and the environment. In this work, literature analysis, comparative analysis and statistical induction are carried out to illustrate a constraint mechanism of environmental regulation on carbon emission. Based on literature reports and government yearbook data, the impacts of environmental regulations on carbon emissions of heavy industry in Chengdu-Chongqing region are studied. Analysis and demonstration are carried out from four dimensions: corporate identity, technological progress, policy constraints, and government supervision. The predicament of environmental regulation affecting heavy industry carbon emission reduction is expounded and puts forward reasonable policy suggestions. The research results can enrich the theory of environmental regulation, and provide policy suggestions for optimizing the green transformation of heavy industry

Study on the Effect of Regional Water Pollution—Take Huaxi River in Chongqing as an Example

Water pollution management plays a crucial role in China’s ecological environment development. It has evolved from being solely the responsibility of the government to a collaborative effort involving multiple entities. This paper presents findings from a field survey conducted around the collaborative capacity and effectiveness of wastewater treatment in Huaxi River, Chongqing. The study collected 427 valid questionnaires and employed SPSS26.0 software and AMOS24.0 software, utilizing structural equation modelling and regression analysis to verify the relationship between the variables. The results highlight that synergy mechanism acts as a mediating variable between synergy capability and synergy governance effect, underscoring the role of mechanism in the relationship between capability and governance effect. The conclusion emphasizes the importance of enhancing synergistic capacity and synergistic mechanism to effectively promote synergistic governance effect in the water pollution management of Huaxi River in Chongqing. This can be achieved by improving the abilities of multiple stakeholders in managing water pollution, enhancing cooperation among parties, and encouraging participation of social organizations, the public, and enterprises in the management process to achieve sustainable development of ecological civilization

Determination of Eu(III) based on fluorescence and cofluorescence enhancement of Eu(III)-Tb(III)-tetracycline-citrate system

1801-1804A new sensitized cofluorescence system has been developed for the determination of Eu(III) based on its complex formation with tetracycline (TC) in the presence of citrate and Tb(III). Eu(III) forms complex with tetracycline in alkaline condition which emits intrinsic fluorescence of Eu(III) when excited. The fluorescence intensity of Eu(III)TC is enhanced about 5 times when citrate and Tb(III) are introduced. The factors that influence the fluorescence intensity of the system have been studied in detail. Under optimum conditions, the relative fluorescence intensity is linear in over the range 6.0×10⁻⁹ to 4.0×10⁻⁶ M of Eu(III). The detection limit has been found to be 1.4×10⁻⁹ M of Eu(III). The method has been used for the determination of Eu in two rare earth samples with relative error 4.5% and -1.8%, and RSD 2.6% and 2.1%, respectively

Characterization and photophysical properties of lanthanide macrocyclic complexes derived from (2,1)

The isolation and characterization of Ln(NO3)3 complexes (Ln=La, Pr, Nd, Eu, Tb, Lu) with 2,3-benzo-1,4,7,13-tetraoxa-10-azacyclo-penta-decane (L1) and two of its N-substituted derivatives (L2, L3) are reported. Structural information in the solid state is derived from spectroscopic data (vibrational, absorption, reflectance and luminescence spectra). Both ligand- and metal-centered luminescence of solutions of the complexes in oxygen-free and anhydrous acetonitrile are investigated. Substitution of the N–proton of the crown ether enhances metal emission. Ligand L2 displays a good antenna effect for EuIII luminescence, while L3 is especially effective in transferring energy from its triplet state onto the excited states of TbIII. The EuIII site in Eu(NO3)3L2·0.5C2H5OH·1.5H2O possesses a low local symmetry and a relatively long 5D0 lifetime (1.01 ms)

USP35 promotes HCC development by stabilizing ABHD17C and activating the PI3K/AKT signaling pathway

Abstract S-palmitoylation is a reversible protein lipidation that controls the subcellular localization and function of targeted proteins, including oncogenes such as N-RAS. The depalmitoylation enzyme family ABHD17s can remove the S-palmitoylation from N-RAS to facilitate cancer development. We previously showed that ABHD17C has oncogenic roles in hepatocellular carcinoma (HCC) cells, and its mRNA stability is controlled by miR-145-5p. However, it is still unclear whether ABHD17C is regulated at the post-translational level. In the present study, we identified multiple ubiquitin-specific proteases (USPs) that can stabilize ABHD17C by inhibiting the ubiquitin-proteasome-mediated degradation. Among them, USP35 is the most potent stabilizer of ABHD17C. We found a positive correlation between the elevated expression levels of USP35 and ABHD17C, together with their association with increased PI3K/AKT pathway activity in HCCs. USP35 knockdown caused decreased ABHD17C protein level, impaired PI3K/AKT pathway, reduced proliferation, cell cycle arrest, increased apoptosis, and mitigated migration and invasion. USP35 can interact with and stabilize ABHD17C by inhibiting its ubiquitination. Overexpression of ABHD17C can rescue the defects caused by USP35 knockdown in HCC cells. In support of these in vitro observations, xenograft assay data also showed that USP35 deficiency repressed HCC development in vivo, characterized by reduced proliferation and disrupted PI3K/AKT signaling. Together, these findings demonstrate that USP35 may promote HCC development by stabilization of ABHD17C and activation of the PI3K/AKT pathway