Antioxidant parameters and cognitive function according to individual GST genotype.

<p>General linear model used. Data are presented as the mean ± SE. For antioxidant biomarker data analysis, factors including age, sex, BMI, smoking and antioxidant supplement were adjusted. For cognitive function (MoCA score) data analysis, factors including age, sex, BMI, education, family history of AD, physical activity and participation in cognitive activity were adjusted. GSH-Px, glutathione peroxidase; GST, glutathione S-transferase; GR, glutathion reductase; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; T-AOC, total antioxidant capacity; MoCA, Montreal Cognitive Assessment. <i>P</i> value<0.05 was considered as significant.</p><p>Antioxidant parameters and cognitive function according to individual GST genotype.</p

Graphic presentation of the overall design.

<p>Graphic presentation of the overall design.</p

Antioxidant parameters and cognitive function according to FV intake.

<p>General linear model used. Data are presented as the mean ± SE. For antioxidant biomarker data analysis, factors including age, sex, BMI, smoking and antioxidant supplement were adjusted. For cognitive function (MoCA score) data analysis, factors including age, sex, BMI, education, family history of AD, physical activity and participation in cognitive activity were adjusted. FV, fruit and vegetable; GSH-Px, glutathione peroxidase; GST, glutathione S-transferase; GR, glutathion reductase; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; T-AOC, total antioxidant capacity; MoCA, Montreal Cognitive Assessment. <i>P</i> value<0.05 was considered as significant.</p><p>Antioxidant parameters and cognitive function according to FV intake.</p

Antioxidant parameters and cognitive function according to FV consumption and individual GST genotype.

<p>General linear model used. Data are presented as the mean ± SE. For antioxidant biomarker data analysis, factors including age, sex, BMI, smoking and antioxidant supplement were adjusted. For cognitive function (MoCA score) data analysis, factors including age, sex, BMI, education, family history of AD, physical activity and participation in cognitive activity were adjusted. FV, fruit and vegetable; GSH-Px, glutathione peroxidase; GST, glutathione S-transferase; GR, glutathion reductase; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; T-AOC, total antioxidant capacity; MoCA, Montreal Cognitive Assessment. <i>P</i> value<0.05 was considered as significant.</p>a<p>: GSTM1 genotype affect the erythrocyte GST enzyme activity, <i>P_{GSTM1 genotype}</i> = 0.012, <0.05.</p>b<p>: FV consumption affect the plasma T-AOC in the subjects with different GSTT1 genotypes, <i>P_FV</i> = 0.04, <0.05.</p>c<p>: Interaction of FV and GSTT1 genotype on cognitive function was detected, <i>P_{FV and GSTT1 genotype interaction}</i> = 0.033, <0.05.</p><p>Antioxidant parameters and cognitive function according to FV consumption and individual GST genotype.</p

Antioxidant parameters and cognitive function according to combined GST genotype.

<p>General linear model used. Data are presented as the mean ± SE. For antioxidant biomarker data analysis, factors including age, sex, BMI, smoking and antioxidant supplement were adjusted. For cognitive function (MoCA score) data analysis, factors including age, sex, BMI, education, family history of AD, physical activity and participation in cognitive activity were adjusted. GSH-Px, glutathione peroxidase; GST, glutathione S-transferase; GR, glutathion reductase; CAT, catalase; SOD, superoxide dismutase; GSH, glutathione; T-AOC, total antioxidant capacity; MoCA, Montreal Cognitive Assessment. <i>P</i> value<0.05 was considered as significant.</p><p>Antioxidant parameters and cognitive function according to combined GST genotype.</p

Unadjusted demographic characteristics of the participants.

<p>The data of age and BMI were expressed as mean ± SE. BMI: body mass index. One-way ANOVA analysis was used to analyze the means of age and BMI.</p><p>Unadjusted demographic characteristics of the participants.</p