Electrical Power Exchange in GMS and Its Influence on Power Systems in Vietnam and Thailand

The paper aims to identify the development of power interconnection network in the Greater Mekong Sub-region (GMS) which is a part of the major energy infrastructure mandated by ASEAN delegates in 1997. An overview of power systems in the region is introduced. The combined load curve for Vietnam and Thailand are formed to show the benefit of power grid interconnection of GMS. The paper also concentrates on simulation, analysis and evaluation of power transfer in 500kV and 220kV interconnection transmission lines in GMS for the planning horizon of 2010-2020. Reliability and environmental benefits of the interconnection are discussed due to interconnection. Based on the simulation results few recommendations are given

ASSESSING THE POTENTIAL OF COMMUNITY-BASED ECOTOURISM TOWARD SUSTAINABLE DEVELOPMENT: A CASE STUDY IN TUA CHUA KARST PLATEAU – DIEN BIEN – VIET NAM

Tua Chua Karst Plateau - a living area of the Mong ethnic group with spectacular natural landscapes, cool weather, and unique indigenous cultural values. They are all prerequisites for tourism development. This study aims to evaluate the potential of community-based ecotourism development in the Tua Chua Karst Plateau. This research uses the AHP method. Evaluation criteria include (i) uniqueness of natural landscape, (ii) indigenous cultural value, (iii) stakeholder engagement, (iv) local tourism development policy, (v) quality of infrastructure, (vi) quality of tourism facilities, (vii) accessibility, (viii) connectivity. The evaluation system includes eight criteria that have classified tourism resources according to each resource point and identified suitable internal and external potentials to exploit the geological value of the plateau and preserve indigenous culture. Results of this study reveal that the indigenous cultural values, the participation of local communities, and the uniqueness of the natural landscape have an important impact on the development of ecotourism. Tua Chua Karst Plateau has great potential for community-based ecotourism development with 14 tourist resource sites, of which 8 are highly appreciated

Depression, anxiety and stress among healthcare workers in the context of the COVID-19 pandemic: a cross-sectional study in a tertiary hospital in Northern Vietnam

IntroductionThe outbreak of coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) had significant effects on the mental well-being in general, particularly for healthcare professionals. This study examined the prevalence of depression, anxiety, and stress, and identified the associated risk factors amongst healthcare workers during the COVID-19 outbreak in a tertiary hospital located in Vietnam.MethodsWe conducted a cross-sectional study at a tertiary-level hospital, where the Depression Anxiety and Stress Scale 21 (DASS-21) web-based questionnaire was employed. We analyzed the determinant factors by employing multivariate logistic models.ResultsThe prevalence of depression, anxiety, and stress symptoms were 19.2%, 24.7%, and 13.9%, respectively. Factors such as engaging in shift work during the pandemic, taking care of patients with COVID-19, and staff’s health status were associated with mental health issues among health professionals. In addition, having alternate rest periods was likely to reduce the risk of stress.ConclusionThe prevalence of mental health problems in healthcare workers during the COVID-19 pandemic was relatively high. Having resting periods could potentially mitigate the development of stress among health professionals. Our findings could be taken into account for improving mental health of the health professional population

De novo copy number variations in candidate genomic regions in patients of severe autism spectrum disorder in Vietnam

Autism spectrum disorder (ASD) is a developmental disorder with a prevalence of around 1% children worldwide and characterized by patient behaviour (communication, social interaction, and personal development). Data on the efficacy of diagnostic tests using copy number variations (CNVs) in candidate genes in ASD is currently around 10% but it is overrepresented by patients of Caucasian background. We report here that the diagnostic success of de novo candidate CNVs in Vietnamese ASD patients is around 6%. We recruited one hundred trios (both parents and a child) where the child was clinically diagnosed with ASD while the parents were not affected. We performed genetic screening to exclude RETT syndrome and Fragile X syndrome and performed genome-wide DNA microarray (aCGH) on all probands and their parents to analyse for de novo CNVs. We detected 1708 non-redundant CNVs in 100 patients and 118 (7%) of them were de novo. Using the filter for known CNVs from the Simons Foundation Autism Research Initiative (SFARI) database, we identified six CNVs (one gain and five loss CNVs) in six patients (3 males and 3 females). Notably, 3 of our patients had a deletion involving the SHANK3 gene–which is the highest compared to previous reports. This is the first report of candidate CNVs in ASD patients from Vietnam and provides the framework for building a CNV based test as the first tier screening for clinical management

Expansion of KPC-producing Enterobacterales in four large hospitals in Hanoi, Vietnam

Objectives : The incidence of carbapenem resistance among nosocomial Gram-negative bacteria in Vietnam is high and increasing, including among Enterobacterales. In this study, we assessed the presence of one of the main carbapenemase genes, blaKPC, among carbapenem-resistant Enterobacterales (CRE) from four large hospitals in Hanoi, Vietnam, between 2010 and 2015, and described their key molecular characteristics. Methods : KPC-producing Enterobacterales were detected using conventional PCR and were further analysed using S1 nuclease pulsed-field gel electrophoresis (S1-PFGE), Southern blotting and whole-genome sequencing (WGS) for sequence typing and genetic characterisation. Results : blaKPC genes were detected in 122 (20.4%) of 599 CRE isolates. blaKPC-carrying plasmids were diverse in size. Klebsiella pneumoniae harbouring blaKPC genes belonged to ST15 and ST11, whereas KPC-producing Escherichia coli showed more diverse sequence types including ST3580, ST448, ST709 and ST405. Genotypic relationships supported the hypothesis of circulation of a population of ‘resident’ resistant bacteria in one hospital through the years and of transmission among these hospitals via patient transfer. WGS results revealed co-carriage of several other antimicrobial resistance genes and three different genetic contexts of blaKPC-2. Among these, the combination of ISEcp1–blaCTX-M and ISKpn27–blaKPC–ΔISKpn6 on the same plasmid is reported for the first time. Conclusion : We describe the dissemination of blaKPC-expressing Enterobacterales in four large hospitals in Hanoi, Vietnam, since 2010, which may have started earlier, along with their resistance patterns, sequence types, genotypic relationship, plasmid sizes and genetic context, thereby contributing to the overall picture of the antimicrobial resistance situation in Enterobacterales in Vietnam

Spatiotemporal evolution of SARS-CoV-2 Alpha and Delta variants during large nationwide outbreak of COVID-19, Vietnam, 2021

We analyzed 1,303 SARS-CoV-2 whole-genome sequences from Vietnam, and found the Alpha and Delta variants were responsible for a large nationwide outbreak of COVID-19 in 2021. The Delta variant was confined to the AY.57 lineage and caused >1.7 million infections and >32,000 deaths. Viral transmission was strongly affected by nonpharmaceutical interventions

An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination

Background: Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. Methods and Findings: We carried out a field investigation after adverse events following immunization (AEFI) were reported. We reviewed the clinical data from all cases. S. aureus recovered from skin infections and from nasal and throat swabs were analyzed by pulse-field gel electrophoresis, multi locus sequence typing, PCR and microarray. In May 2006, nine children presented with AEFI, ranging from fatal toxic shock syndrome, necrotizing soft tissue infection, purulent abscesses, to fever with rash. All had received a vaccination injection in different health centres in one District of Ho Chi Minh City. Eight children had been vaccinated by the same health care worker (HCW). Deficiencies in vaccine quality, storage practices, or preparation and delivery were not found. Infection control practices were insufficient. CA-MRSA was cultured in four children and from nasal and throat swabs from the HCW. Strains from children and HCW were indistinguishable. All carried the Panton-Valentine leukocidine (PVL), the staphylococcal enterotoxin B gene, the gene complex for staphylococcal-cassette-chromosome mec type V, and were sequence type 59. Strain HCM3A is epidemiologically unrelated to a strain of ST59 prevalent in the USA, althoughthey belong to the same lineage. Conclusions. We describe an outbreak of infections with CA-MRSA in children, transmitted by an asymptomatic colonized HCW during immunization injection. Consistent adherence to injection practice guidelines is needed to prevent CA-MRSA transmission in both in- and outpatient settings

ỨNG DỤNG GIS VÀ WEBGIS ĐỂ XÂY DỰNG BẢN ĐỒ QUẢN LÝ NHÀ VƯỜN TRUYỀN THỐNG TRONG KINH THÀNH HUẾ

Hue traditional garden houses (HTGHs) are one of the integral factors creating the unique cultural characteristics of Hue City and contribute an essential part to the city’s tourist development. Therefore, we combine GIS and WebGIS applications with GPS, UAV, Adobe Dreamweaver, and Openlayer technologies to construct maps for the HTGHs management in the Citadel area. The WebGIS can be used on smart electronic devices, enabling users to get necessary information about HGTHs. The results allow managers to set up suitable policies for preserving, popularizing and exploiting tourist products based on the traditional garden houses.Nhà vườn truyền thống Huế (NVTTH) là một trong những yếu tố không thể thiếu, tạo nên nét đặc trưng văn hóa của thành phố Huế và đóng góp một phần quan trọng vào phát triển du lịch của địa phương. Nhằm quản lý tốt hơn và phát triển du lịch nhà vườn, chúng tôi ứng dụng GIS và WebGIS kết hợp với công nghệ GPS, UAV, Adobe Dreamweaver và Openlayer để xây dựng bản đồ trên web về các NVTTH trong kinh thành Huế. WebGIS này có thể được sử dụng trên các thiết bị điện tử thông minh, giúp người dùng biết những thông tin cần thiết khi muốn tìm hiểu về các NVTTH. Kết quả nghiên cứu cũng có thể hỗ trợ các nhà quản lý trong việc đưa ra những chính sách phù hợp nhằm bảo tồn, quảng bá và khai thác các sản phẩm du lịch nhà vườn

Supramolecular Gels Incorporating Cordyline terminalis Leaf Extract as a Polyphenol Release Scaffold for Biomedical Applications

Cordyline terminalis leaf extract (aqCT) possesses abundant polyphenols and other bioactive compounds, which are encapsulated in gelatin–polyethylene glycol–tyramine (GPT)/alpha-cyclodextrin (α-CD) gels to form the additional functional materials for biomedical applications. In this study, the gel compositions are optimized, and the GPT/α-CD ratios equal to or less than one half for solidification are found. The gelation time varies from 40.7 min to 5.0 h depending on the increase in GPT/α-CD ratios and aqCT amount. The aqCT extract disturbs the hydrogen bonding and host–guest inclusion of GPT/α-CD gel networks, postponing the gelation. Scanning electron microscope observation shows that all gels with or without aqCT possess a microarchitecture and porosity. GPT/α-CD/aqCT gels could release polyphenols from 110 to 350 nmol/mL at the first hour and sustainably from 5.5 to 20.2 nmol/mL for the following hours, which is controlled by feeding the aqCT amount and gel properties. GPT/α-CD/aqCT gels achieved significant antioxidant activity through a 100% scavenging DPPH radical. In addition, all gels are non-cytotoxic with a cell viability more than 85%. Especially, the GPT3.75α-CD10.5aqCT gels with aqCT amount of 3.1–12.5 mg/mL immensely enhanced the cell proliferation of GPT3.75α-CD10.5 gel without extract. These results suggest that the inherent bioactivities of aqCT endowed the resulting GPT/α-CD/aqCT gels with effective antioxidant and high biocompatibility, and natural polyphenols sustainably release a unique platform for a drug delivery system or other biomedical applications

Overview of the Uncertainty and Supply Chain Risk in Vietnamese Garment and Textile Firms: The Moderating Role of Supply Chain Flexibility in Risk Mitigation

To stay competitive in the market, firms are forced to offer high levels of customization and product offerings, which leads to high uncertainty in the supply chain. Consequently, in uncertain environment, firms would face the risk of supply disruptions, production, and delivery delays, resulting in poor operational performance.  This paper aims to analyze and review the literature on operational uncertainty and risks in the supply chain that enterprises face. On that basis, the study outlines research gaps and future research needs. Keywords: Supply chain risk; Environmental uncertainty; Supply chain flexibility DOI: 10.7176/JESD/13-7-01 Publication date: April 30th 202