Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-0

<p><b>Copyright information:</b></p><p>Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"</p><p>BMC Genomics 2006;7():74-74.</p><p>Published online 5 Apr 2006</p><p>PMCID:PMC1458327.</p><p>Copyright © 2006 Qian et al; licensee BioMed Central Ltd.</p>AST hits (statistically significant) were used as input. MEGA3 program was used to perform this analysis. NJ trees were constructed using PC (Poisson Correlation) distance and a bootstrap value of 500. After deleting distant branches (homologs but not orthologs), final tree generated. Figure 1a depicts Tar/TagA orthologs. Figure 1b depicts Tar/TagD orthologs. Figure 1c depicts double TarI orthologs in each strain. Figure 1d depicts double TarJ orthologs in each strain. Figure 1e depicts orthologs of Tar/TagB, Tar/TagF, TarL and once again, two orthologs of TarL in each strain are found. However, there is no ortholog of TarK

Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-4

<p><b>Copyright information:</b></p><p>Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"</p><p>BMC Genomics 2006;7():74-74.</p><p>Published online 5 Apr 2006</p><p>PMCID:PMC1458327.</p><p>Copyright © 2006 Qian et al; licensee BioMed Central Ltd.</p>s clearly shown. The high homology also indicates this duplication should not be a remote event. And part of region is less conserved, which indicate that two copies could have different functions. This phenomenon can be used to explain why there is no homologs of in these strains. Other strains give similar results and are not shown here

Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-3

<p><b>Copyright information:</b></p><p>Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"</p><p>BMC Genomics 2006;7():74-74.</p><p>Published online 5 Apr 2006</p><p>PMCID:PMC1458327.</p><p>Copyright © 2006 Qian et al; licensee BioMed Central Ltd.</p>ince they have similar genomic organization (See for complete figure). The top line of this figure shows the divergon organizations of W23 and 168 as a reference. The following two lines represented in arrows are graphic demonstration of genomic organization of the selected two strains. Arrows in different colours represent different genes as illustrated by the colour table at the bottom. The length of each arrow is defined accurately by the scale, demonstrating the exact amino acid length of each gene. All six strains share a similar genomic organization, which is quite different from W23 and 168 counterparts. GenBank gi numbers are indicated

Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-2

<p><b>Copyright information:</b></p><p>Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"</p><p>BMC Genomics 2006;7():74-74.</p><p>Published online 5 Apr 2006</p><p>PMCID:PMC1458327.</p><p>Copyright © 2006 Qian et al; licensee BioMed Central Ltd.</p>n in other strains (red arrow), which is suspected as an annotation error. So ORF finder program was rerun on this region and new_tarBs in Mu50 and N315 were identified. As shown in figure, new_tar

Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication-5

<p><b>Copyright information:</b></p><p>Taken from "Genomic characterization of ribitol teichoic acid synthesis in : genes, genomic organization and gene duplication"</p><p>BMC Genomics 2006;7():74-74.</p><p>Published online 5 Apr 2006</p><p>PMCID:PMC1458327.</p><p>Copyright © 2006 Qian et al; licensee BioMed Central Ltd.</p>TarL as a one step (bottom blocks)

Additional file 1: Table S4. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Meta-analysis of 130 HU CAC scores in AA-DHS and JHS. (XLSX 230 kb

Additional file 3: Table S1. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

List of SNPs with meta-analysis p-value less than 10–4. (XLSX 190 kb

Additional file 2: Table S3. of Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Replication of AA-DHS admixture mapping results in JHS. (XLSX 11 kb

Study Design.

<p>Study Design.</p

Clinical Characteristics of Study Samples.

<p>Values are presented as trait mean and standard deviation.</p